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Protein
Submitted name:

DNA polymerase alpha subunit B

Gene

POLA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase alpha subunit BImported
Gene namesi
Name:POLA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000014138.8
HGNCiHGNC:30073 POLA2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000014138

PTM / Processingi

Proteomic databases

EPDiE9PIQ6
MaxQBiE9PIQ6
PeptideAtlasiE9PIQ6
PRIDEiE9PIQ6

Expressioni

Gene expression databases

BgeeiENSG00000014138 Expressed in 168 organ(s), highest expression level in embryo
ExpressionAtlasiE9PIQ6 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1625 Eukaryota
COG5214 LUCA
GeneTreeiENSGT00390000016784

Family and domain databases

InterProiView protein in InterPro
IPR016722 DNA_pol_alpha_bsu
PANTHERiPTHR23061 PTHR23061, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9PIQ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGELIAFCT STHKVGLTSE ILNSFEHEFL SKRLSKARHS TCKDSGHAGA
60 70 80 90 100
RDIVSIQELI EVEEEEEILL NSYTTPSKGS QKRAISTPET PLTKRSVSTR
110 120 130 140
SPHQLLSPSS FSPSATPSQK YNSRSNRGEV VTSFGLAQGV SWSGRG
Length:146
Mass (Da):15,895
Last modified:April 5, 2011 - v1
Checksum:i9263B1C6D8526A8F
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q14181DPOA2_HUMAN
DNA polymerase alpha subunit B
POLA2
598Annotation score:
H0YDR7H0YDR7_HUMAN
DNA polymerase alpha subunit B
POLA2
261Annotation score:
E9PQ99E9PQ99_HUMAN
DNA polymerase alpha subunit B
POLA2
37Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei146Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000944 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000532391; ENSP00000433952; ENSG00000014138
UCSCiuc058dif.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000944 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiE9PIQ6
MaxQBiE9PIQ6
PeptideAtlasiE9PIQ6
PRIDEiE9PIQ6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000532391; ENSP00000433952; ENSG00000014138
UCSCiuc058dif.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000014138.8
HGNCiHGNC:30073 POLA2
OpenTargetsiENSG00000014138
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1625 Eukaryota
COG5214 LUCA
GeneTreeiENSGT00390000016784

Miscellaneous databases

ChiTaRSiPOLA2 human

Gene expression databases

BgeeiENSG00000014138 Expressed in 168 organ(s), highest expression level in embryo
ExpressionAtlasiE9PIQ6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016722 DNA_pol_alpha_bsu
PANTHERiPTHR23061 PTHR23061, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PIQ6_HUMAN
AccessioniPrimary (citable) accession number: E9PIQ6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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