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Protein
Submitted name:

Transmembrane protein 25

Gene

TMEM25

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Transmembrane protein 25Imported
Gene namesi
Name:TMEM25Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149582.15
HGNCiHGNC:25890 TMEM25

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149582

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500324407327 – 138Sequence analysisAdd BLAST112

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiE9PI73

Expressioni

Gene expression databases

BgeeiENSG00000149582 Expressed in 150 organ(s), highest expression level in cerebellum
ExpressionAtlasiE9PI73 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PI73
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 123Ig-likeInterPro annotationAdd BLAST94

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IF2Y Eukaryota
ENOG410ZNWF LUCA
GeneTreeiENSGT00390000003414

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013162 CD80_C2-set
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF08205 C2-set_2, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

E9PI73-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALPPGPAAL RHTLLLLPAL LSSGWGELEP QIDGQTWAER ALRENERHAF
60 70 80 90 100
TCRVAGGPGT PRLAWYLDGQ LQEASTSRLL SVGGEAFSGG TSTFTVTAHR
110 120 130
AQHELNCSLQ DPRSGRSANA SVILNVQFKP EIAQVGAK
Length:138
Mass (Da):14,742
Last modified:April 5, 2011 - v1
Checksum:iA740087272990058
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q86YD3TMM25_HUMAN
Transmembrane protein 25
TMEM25 UNQ2531/PRO6030
366Annotation score:
E9PKP3E9PKP3_HUMAN
Transmembrane protein 25
TMEM25
381Annotation score:
E9PIE6E9PIE6_HUMAN
Transmembrane protein 25
TMEM25
167Annotation score:
H0YC87H0YC87_HUMAN
Transmembrane protein 25
TMEM25
200Annotation score:
E9PIT4E9PIT4_HUMAN
Transmembrane protein 25
TMEM25
168Annotation score:
E9PIR4E9PIR4_HUMAN
Transmembrane protein 25
TMEM25
170Annotation score:
E9PK88E9PK88_HUMAN
Transmembrane protein 25
TMEM25
40Annotation score:
E9PK43E9PK43_HUMAN
Transmembrane protein 25
TMEM25
49Annotation score:
H0YD63H0YD63_HUMAN
Transmembrane protein 25
TMEM25
194Annotation score:
E9PID6E9PID6_HUMAN
Transmembrane protein 25
TMEM25
37Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei138Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000941 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000533689; ENSP00000436746; ENSG00000149582
UCSCiuc058hzl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000941 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PI73
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE9PI73

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000533689; ENSP00000436746; ENSG00000149582
UCSCiuc058hzl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000149582.15
HGNCiHGNC:25890 TMEM25
OpenTargetsiENSG00000149582
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IF2Y Eukaryota
ENOG410ZNWF LUCA
GeneTreeiENSGT00390000003414

Miscellaneous databases

ChiTaRSiTMEM25 human

Gene expression databases

BgeeiENSG00000149582 Expressed in 150 organ(s), highest expression level in cerebellum
ExpressionAtlasiE9PI73 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013162 CD80_C2-set
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF08205 C2-set_2, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PI73_HUMAN
AccessioniPrimary (citable) accession number: E9PI73
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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