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Protein
Submitted name:

Transcription factor 4, isoform CRA_e

Gene

TCF4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor 4, isoform CRA_eImported
Gene namesi
Name:TCF4Imported
ORF Names:hCG_1811800Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000196628.13
HGNCiHGNC:11634 TCF4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196628

PTM / Processingi

Proteomic databases

EPDiE9PH57
PRIDEiE9PH57

Expressioni

Gene expression databases

BgeeiENSG00000196628
ExpressionAtlasiE9PH57 baseline and differential

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

IntActiE9PH57, 2 interactors

Structurei

3D structure databases

SMRiE9PH57
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini670 – 723BHLHInterPro annotationAdd BLAST54

Phylogenomic databases

eggNOGiKOG3910 Eukaryota
ENOG410XYUA LUCA
GeneTreeiENSGT00510000046438
OMAiSNHMGQM
OrthoDBiEOG091G07E2

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

E9PH57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSKRLEKIP QVPLLFPFIF IILTNYSKME GAVESQPSFF KTSQDIVTCT
60 70 80 90 100
WVENCYSSFS RRPLEQMFCK HQSKNIISWT GMVAHTCNPS TLGGQGLCDF
110 120 130 140 150
AKMHHQQRMA ALGTDKELSD LLDFSAMFSP PVSSGKNGPT SLASGHFTGS
160 170 180 190 200
NVEDRSSSGS WGNGGHPSPS RNYGDGTPYD HMTSRDLGSH DNLSPPFVNS
210 220 230 240 250
RIQSKTERGS YSSYGRESNL QGCHQQSLLG GDMDMGNPGT LSPTKPGSQY
260 270 280 290 300
YQYSSNNPRR RPLHSSAMEV QTKKVRKVPP GLPSSVYAPS ASTADYNRDS
310 320 330 340 350
PGYPSSKPAT STFPSSFFMQ DGHHSSDPWS SSSGMNQPGY AGMLGNSSHI
360 370 380 390 400
PQSSSYCSLH PHERLSYPSH SSADINSSLP PMSTFHRSGT NHYSTSSCTP
410 420 430 440 450
PANGTDSIMA NRGSGAAGSS QTGDALGKAL ASIYSPDHTN NSFSSNPSTP
460 470 480 490 500
VGSPPSLSAG TAVWSRNGGQ ASSSPNYEGP LHSLQSRIED RLERLDDAIH
510 520 530 540 550
VLRNHAVGPS TAMPGGHGDM HGIIGPSHNG AMGGLGSGYG TGLLSANRHS
560 570 580 590 600
LMVGTHREDG VALRGSHSLL PNQVPVPQLP VQSATSPDLN PPQDPYRGMP
610 620 630 640 650
PGLQGQSVSS GSSEIKSDDE GDENLQDTKS SEDKKLDDDK KDIKSITRSR
660 670 680 690 700
SSNNDDEDLT PEQKAEREKE RRMANNARER LRVRDINEAF KELGRMVQLH
710 720 730 740 750
LKSDKPQTKL LILHQAVAVI LSLEQQVRER NLNPKAACLK RREEEKVSSE
760 770
PPPLSLAGPH PGMGDASNHM GQM
Length:773
Mass (Da):83,426
Last modified:October 29, 2014 - v2
Checksum:i18FDDD76D52E62AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013587 Genomic DNA No translation available.
AC018994 Genomic DNA No translation available.
AC090383 Genomic DNA No translation available.
AC090684 Genomic DNA No translation available.
AC091103 Genomic DNA No translation available.
KF459816 Genomic DNA No translation available.
CH471096 Genomic DNA Translation: EAW63021.1
RefSeqiNP_001230155.2, NM_001243226.2
UniGeneiHs.605153
Hs.742885

Genome annotation databases

EnsembliENST00000398339; ENSP00000381382; ENSG00000196628
GeneIDi6925
UCSCiuc002lga.4 human

Similar proteinsi

Entry informationi

Entry nameiE9PH57_HUMAN
AccessioniPrimary (citable) accession number: E9PH57
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 29, 2014
Last modified: July 18, 2018
This is version 70 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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