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Protein
Submitted name:

Transforming acidic coiled-coil-containing protein 2

Gene

TACC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming acidic coiled-coil-containing protein 2Imported
Gene namesi
Name:TACC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000138162.18
HGNCiHGNC:11523 TACC2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138162

PTM / Processingi

Proteomic databases

MaxQBiE9PGB3
PeptideAtlasiE9PGB3
PRIDEiE9PGB3

Expressioni

Gene expression databases

BgeeiENSG00000138162 Expressed in 222 organ(s), highest expression level in chorionic villus
ExpressionAtlasiE9PGB3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PGB3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IIVK Eukaryota
ENOG410YMFS LUCA
GeneTreeiENSGT00530000063855

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

E9PGB3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAYASWQRWS PVEWARWMWT AVTSSGDSSL LVLQGDSGKR SSDSEEAFET
60 70 80 90 100
PESTTPVKAP PAPPPPPPEV IPEPEVSTQP PPEEPGCGSE TVPVPDGPRS
110 120 130 140 150
DSVEGSPFRP PSHSFSAVFD EDKPIASSGT YNLDFDNIEL VDTFQTLEPR
160 170 180 190 200
ASDAKNQEGK VNTRRKSTDS VPISKSTLSR SLSLQASDFD GASSSGNPEA
210 220 230 240 250
VALAPDAYST GSSSASSTLK RTKKPRPPSL KKKQTTKKPT ETPPVKETQQ
260 270 280 290 300
EPDEESLVPS GENLASETKT ESAKTEGPSP ALLEETPLEP AVGPKAACPL
310 320 330 340 350
DSESAEGVVP PASGGGRVQN SPPVGRKTLP LTTAPEAGEV TPSDSGGQED
360 370 380 390 400
SPAKGLSVRL EFDYSEDKSS WDNQQENPPP TKKIGKKPVA KMPLRRPKMK
410 420 430 440 450
KTPEKLDNTP ASPPRSPAEP NDIPIAKGTY TFDIDKWDDP NFNPFSSTSK
460 470 480 490 500
MQESPKLPQQ SYNFDPDTCD ESVDPFKTSS KTPSSPSKSP ASFEIPASAM
510 520 530 540 550
EANGVDGDGL NKPAKKKKTP LKTDTFRVKK SPKRSPLSDP PSQDPTPAAT
560 570 580 590 600
PETPPVISAV VHATDEEKLA VTNQKWTCMT VDLEADKQDY PQPSDLSTFV
610 620 630 640 650
NETKFSSPTE ELDYRNSYEI EYMEKIGSSL PQDDDAPKKQ ALYLMFDTSQ
660
ESPVKSSPVR MSESPTPCS
Length:669
Mass (Da):72,093
Last modified:April 5, 2011 - v1
Checksum:iFCBAEF3C5F7C97E0
GO

Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O95359TACC2_HUMAN
Transforming acidic coiled-coil-con...
TACC2
2,948Annotation score:
Q4VXL8Q4VXL8_HUMAN
Transforming acidic coiled-coil-con...
TACC2
1,038Annotation score:
Q4VXL4Q4VXL4_HUMAN
HCG41426, isoform CRA_c
TACC2 hCG_41426
575Annotation score:
D6RAA5D6RAA5_HUMAN
Transforming acidic coiled-coil-con...
TACC2
1,008Annotation score:
E7EMZ9E7EMZ9_HUMAN
Transforming acidic coiled-coil-con...
TACC2
2,826Annotation score:
E9PBC6E9PBC6_HUMAN
Transforming acidic coiled-coil-con...
TACC2
2,875Annotation score:
H0Y911H0Y911_HUMAN
Transforming acidic coiled-coil-con...
TACC2
409Annotation score:
H0Y9C3H0Y9C3_HUMAN
Transforming acidic coiled-coil-con...
TACC2
153Annotation score:
A0A0U1RRM9A0A0U1RRM9_HUMAN
Transforming acidic coiled-coil-con...
TACC2
175Annotation score:
H0Y8P9H0Y8P9_HUMAN
Transforming acidic coiled-coil-con...
TACC2
184Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei669Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063960 Genomic DNA No translation available.
AL135793 Genomic DNA No translation available.
AL731566 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000514539; ENSP00000420967; ENSG00000138162
UCSCiuc057wmv.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063960 Genomic DNA No translation available.
AL135793 Genomic DNA No translation available.
AL731566 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PGB3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PGB3
PeptideAtlasiE9PGB3
PRIDEiE9PGB3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000514539; ENSP00000420967; ENSG00000138162
UCSCiuc057wmv.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000138162.18
HGNCiHGNC:11523 TACC2
OpenTargetsiENSG00000138162
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IIVK Eukaryota
ENOG410YMFS LUCA
GeneTreeiENSGT00530000063855

Miscellaneous databases

ChiTaRSiTACC2 human

Gene expression databases

BgeeiENSG00000138162 Expressed in 222 organ(s), highest expression level in chorionic villus
ExpressionAtlasiE9PGB3 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiE9PGB3_HUMAN
AccessioniPrimary (citable) accession number: E9PGB3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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