UniProtKB - E9PFK5 (E9PFK5_HUMAN)
Protein
Submitted name:
Nucleolar protein 14
Gene
NOP14
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- ribosome biogenesis Source: UniProtKB-KW
Keywordsi
Biological process | Ribosome biogenesisARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Nucleolar protein 14Imported |
Gene namesi | Name:NOP14Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16821, NOP14 |
VEuPathDBi | HostDB:ENSG00000087269.15 |
Subcellular locationi
Nucleus
- nucleolus ARBA annotation
Nucleus
- nucleolus Source: HPA
- nucleoplasm Source: HPA
Other locations
- small-subunit processome Source: InterPro
Keywords - Cellular componenti
NucleusARBA annotationPTM / Processingi
Proteomic databases
EPDi | E9PFK5 |
MaxQBi | E9PFK5 |
PeptideAtlasi | E9PFK5 |
PRIDEi | E9PFK5 |
ProteomicsDBi | 20122 |
Expressioni
Gene expression databases
Bgeei | ENSG00000087269, Expressed in oviduct epithelium and 210 other tissues |
ExpressionAtlasi | E9PFK5, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 34 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 162 – 252 | DisorderedSequence analysisAdd BLAST | 91 | |
Regioni | 264 – 422 | DisorderedSequence analysisAdd BLAST | 159 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 57 – 77 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 175 – 252 | PolyampholyteSequence analysisAdd BLAST | 78 | |
Compositional biasi | 274 – 352 | PolyampholyteSequence analysisAdd BLAST | 79 | |
Compositional biasi | 353 – 376 | AcidicSequence analysisAdd BLAST | 24 | |
Compositional biasi | 377 – 400 | PolyampholyteSequence analysisAdd BLAST | 24 |
Sequence similaritiesi
Belongs to the NOP14 family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00390000017459 |
Family and domain databases
InterProi | View protein in InterPro IPR007276, Nop14 |
PANTHERi | PTHR23183, PTHR23183, 1 hit |
Pfami | View protein in Pfam PF04147, Nop14, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
E9PFK5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKAKKVGAR RKASGAPAGA RGGPAKANSN PFEVKVNRQK FQILGRKTRH
60 70 80 90 100
DVGLPGVSRA RALRKRTQTL LKEYKERDKS NVFRDKRFGE YNSNMSPEEK
110 120 130 140 150
MMKRFALEQQ RHHEKKSIYN LNEDEELTHY GQSLADIEKH NDIVDSDSDA
160 170 180 190 200
EDRGTLSAEL TAAHFGGGGG LLHKKTQQEG EEREKPKSRK ELIEELIAKS
210 220 230 240 250
KQEKRERQAQ REDALELTEK LDQDWKEIQT LLSHKTPKSE NRDKKEKPKP
260 270 280 290 300
DAYDMMVREL GFEMKAQPSN RMKTEAELAK EEQEHLRKLE AERLRRMLGK
310 320 330 340 350
DEDENVKKPK HMSADDLNDG FVLDKDDRRL LSYKDGKMNV EEDVQEEQSK
360 370 380 390 400
EASDPESNEE EGDSSGGEDT EESDSPDSHL DLESNVESEE ENEKPAKEQR
410 420 430 440 450
QTPGKGLISG KERAGKATRD ELPYTFAAPE SYEELRSLLL GRSMEEQLLV
460 470 480 490 500
VERIQKCNHP SLAEGNKAKL EKLFGFLLEY VGDLATDDPP DLTVIDKLVV
510 520 530 540 550
HLYHLCQMFP ESASDAIKFV LRDAMHEMEE MIETKGRAAL PGLDVLIYLK
560 570 580 590 600
ITGLLFPTSD FWHPVVTPAL VCLSQLLTKC PILSLQDVVK GLFVCCLFLE
610 620 630 640 650
YVALSQRFIP ELINFLLGIL YIATPNKASQ GSTLVHPFRA LGKNSELLVV
660 670 680 690 700
SAREDVATWQ QSSLSLRWAS RLRAPTSTEA NHIRLSCLAV GLALLKRCVL
710 720 730 740 750
MYGSLPSFHA IMGPLQALLT DHLADCSHPQ ELQELCQSTL TEMESQKQLC
760 770 780
RPLTCEKSKP VPLKLFTPRL AGLEFPTSGN PPALAPQL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketP78316 | NOP14_HUMAN | Nucleolar protein 14 | NOP14 C4orf9, NOL14, RES4-25 | 857 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL390065 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000502735; ENSP00000427415; ENSG00000087269 |
UCSCi | uc062utc.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL390065 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
EPDi | E9PFK5 |
MaxQBi | E9PFK5 |
PeptideAtlasi | E9PFK5 |
PRIDEi | E9PFK5 |
ProteomicsDBi | 20122 |
Protocols and materials databases
Antibodypediai | 22420, 62 antibodies |
Genome annotation databases
Ensembli | ENST00000502735; ENSP00000427415; ENSG00000087269 |
UCSCi | uc062utc.1, human |
Organism-specific databases
HGNCi | HGNC:16821, NOP14 |
OpenTargetsi | ENSG00000087269 |
VEuPathDBi | HostDB:ENSG00000087269.15 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000017459 |
Miscellaneous databases
ChiTaRSi | NOP14, human |
Gene expression databases
Bgeei | ENSG00000087269, Expressed in oviduct epithelium and 210 other tissues |
ExpressionAtlasi | E9PFK5, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR007276, Nop14 |
PANTHERi | PTHR23183, PTHR23183, 1 hit |
Pfami | View protein in Pfam PF04147, Nop14, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E9PFK5_HUMAN | |
Accessioni | E9PFK5Primary (citable) accession number: E9PFK5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 5, 2011 |
Last sequence update: | April 5, 2011 | |
Last modified: | February 10, 2021 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |