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UniProtKB - E9PFI4 (E9PFI4_HUMAN)
Protein
Submitted name:
LIM domain-binding protein 2
Gene
LDB2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- LIM domain binding Source: InterPro
- transcription coregulator activity Source: InterPro
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: LIM domain-binding protein 2 |
Gene namesi | Name:LDB2 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6533, LDB2 |
VEuPathDBi | HostDB:ENSG00000169744 |
Subcellular locationi
Nucleus
- nucleolus Source: HPA
- nucleoplasm Source: HPA
Plasma Membrane
- plasma membrane Source: HPA
PTM / Processingi
Proteomic databases
MaxQBi | E9PFI4 |
PeptideAtlasi | E9PFI4 |
PRIDEi | E9PFI4 |
ProteomicsDBi | 20110 |
Expressioni
Gene expression databases
Bgeei | ENSG00000169744, Expressed in forebrain and 229 other tissues |
ExpressionAtlasi | E9PFI4, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 245 – 286 | DisorderedSequence analysisAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 264 – 286 | Polar residuesSequence analysisAdd BLAST | 23 |
Phylogenomic databases
GeneTreei | ENSGT00390000005639 |
OrthoDBi | 849287at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR030174, LDB2 IPR029005, LIM-bd/SEUSS |
PANTHERi | PTHR10378, PTHR10378, 1 hit PTHR10378:SF8, PTHR10378:SF8, 1 hit |
Pfami | View protein in Pfam PF01803, LIM_bind, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
E9PFI4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSTPHDPFY SSPFGPFYRR HTPYMVQPEY RIYEMNKRLQ SRTEDSDNLW
60 70 80 90 100
WDAFATEFFE DDATLTLSFC LEDGPKRYTI GRTLIPRYFS TVFEGGVTDL
110 120 130 140 150
YYILKHSKES YHNSSITVDC DQCTMVTQHG KPMFTKVCTE GRLILEFTFD
160 170 180 190 200
DLMRIKTWHF TIRQYRELVP RSILAMHAQD PQVLDQLSKN ITRMGLTNFT
210 220 230 240 250
LNYLRLCVIL EPMQELMSRH KTYNLSPRDC LKTCLFQKWQ RMVAPPAEPT
260 270 280 290 300
RQPTTKRRKR KNSTSSTSNS SAGNNANSTG SKKKTTAANL SLSSQVPIAS
310
IARSPVSGCA LRT
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO43679 | LDB2_HUMAN | LIM domain-binding protein 2 | LDB2 CLIM1 | 373 | Annotation score: | ||
G5E9Y7 | G5E9Y7_HUMAN | LIM domain binding 2, isoform CRA_b | LDB2 hCG_1811661 | 371 | Annotation score: | ||
H0YA09 | H0YA09_HUMAN | LIM domain-binding protein 2 | LDB2 | 294 | Annotation score: | ||
D6RAT1 | D6RAT1_HUMAN | LIM domain-binding protein 2 | LDB2 | 164 | Annotation score: | ||
E9PGU0 | E9PGU0_HUMAN | LIM domain-binding protein 2 | LDB2 | 106 | Annotation score: | ||
E7EX95 | E7EX95_HUMAN | LIM domain-binding protein 2 | LDB2 | 110 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005690 Genomic DNA No translation available. AC097515 Genomic DNA No translation available. AC104656 Genomic DNA No translation available. AC105353 Genomic DNA No translation available. AC106894 Genomic DNA No translation available. |
RefSeqi | NP_001291364.1, NM_001304435.1 |
Genome annotation databases
Ensembli | ENST00000502640.5; ENSP00000423963.1; ENSG00000169744.13 |
GeneIDi | 9079 |
UCSCi | uc010iee.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005690 Genomic DNA No translation available. AC097515 Genomic DNA No translation available. AC104656 Genomic DNA No translation available. AC105353 Genomic DNA No translation available. AC106894 Genomic DNA No translation available. |
RefSeqi | NP_001291364.1, NM_001304435.1 |
3D structure databases
SMRi | E9PFI4 |
ModBasei | Search... |
Proteomic databases
MaxQBi | E9PFI4 |
PeptideAtlasi | E9PFI4 |
PRIDEi | E9PFI4 |
ProteomicsDBi | 20110 |
Protocols and materials databases
Antibodypediai | 4310, 235 antibodies from 27 providers |
DNASUi | 9079 |
Genome annotation databases
Ensembli | ENST00000502640.5; ENSP00000423963.1; ENSG00000169744.13 |
GeneIDi | 9079 |
UCSCi | uc010iee.4, human |
Organism-specific databases
CTDi | 9079 |
HGNCi | HGNC:6533, LDB2 |
OpenTargetsi | ENSG00000169744 |
VEuPathDBi | HostDB:ENSG00000169744 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000005639 |
OrthoDBi | 849287at2759 |
Miscellaneous databases
BioGRID-ORCSi | 9079, 6 hits in 1072 CRISPR screens |
ChiTaRSi | LDB2, human |
GenomeRNAii | 9079 |
Gene expression databases
Bgeei | ENSG00000169744, Expressed in forebrain and 229 other tissues |
ExpressionAtlasi | E9PFI4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR030174, LDB2 IPR029005, LIM-bd/SEUSS |
PANTHERi | PTHR10378, PTHR10378, 1 hit PTHR10378:SF8, PTHR10378:SF8, 1 hit |
Pfami | View protein in Pfam PF01803, LIM_bind, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | E9PFI4_HUMAN | |
Accessioni | E9PFI4Primary (citable) accession number: E9PFI4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 5, 2011 |
Last sequence update: | April 5, 2011 | |
Last modified: | May 25, 2022 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |