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Protein
Submitted name:

Nuclear receptor subfamily 1 group I member 3

Gene

NR1I3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi7 – 54Nuclear receptorPROSITE-ProRule annotationAdd BLAST48

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 1 group I member 3Imported
Gene namesi
Name:NR1I3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143257.11
HGNCiHGNC:7969 NR1I3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143257

PTM / Processingi

Proteomic databases

PRIDEiE9PCF2

Expressioni

Gene expression databases

BgeeiENSG00000143257
ExpressionAtlasiE9PCF2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PCF2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 54Nuclear receptorInterPro annotationAdd BLAST48
Domaini80 – 297NR LBDInterPro annotationAdd BLAST218

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00870000136372

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001728 ThyrH_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00546 THYROIDHORMR
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PCF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPKRSRRTV SKSIGPTCPF AGSCEVSKTQ RRHCPACRLQ KCLDAGMRKD
60 70 80 90 100
MILSAEALAL RRAKQAQRRA QQTPVQLSKE QEELIRTLLG AHTRHMGTMF
110 120 130 140 150
EQFVQFRPPA HLFIHHQPLP TLAPVLPLVT HFADINTFMV LQVIKFTKDL
160 170 180 190 200
PVFRSLPIED QISLLKGAAV EICHIVLNTT FCLQTQNFLC GPLRYTIEDG
210 220 230 240 250
ARVGFQVEFL ELLFHFHGTL RKLQLQEPEY VLLAAMALFS PDRPGVTQRD
260 270 280 290
EIDQLQEEMA LTLQSYIKGQ QRRPRDRYGG TLRAWRPHQG RKGLVKH
Length:297
Mass (Da):33,993
Last modified:April 5, 2011 - v1
Checksum:iA82EF34D311A3127
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590714 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000506209; ENSP00000423089; ENSG00000143257
UCSCiuc010pkm.3 human

Similar proteinsi

Entry informationi

Entry nameiE9PCF2_HUMAN
AccessioniPrimary (citable) accession number: E9PCF2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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