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Protein
Submitted name:

Conserved oligomeric Golgi complex subunit 1

Gene

COG1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Conserved oligomeric Golgi complex subunit 1Imported
Gene namesi
Name:COG1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000166685.11
HGNCiHGNC:6545 COG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166685

PTM / Processingi

Proteomic databases

EPDiE9PBL8
MaxQBiE9PBL8
PeptideAtlasiE9PBL8
PRIDEiE9PBL8

Expressioni

Gene expression databases

BgeeiENSG00000166685 Expressed in 196 organ(s), highest expression level in adenohypophysis
ExpressionAtlasiE9PBL8 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiE9PBL8, 2 interactors

Structurei

3D structure databases

ProteinModelPortaliE9PBL8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2033 Eukaryota
ENOG410XR7E LUCA
GeneTreeiENSGT00390000017136

Family and domain databases

InterProiView protein in InterPro
IPR033370 COG1
PANTHERiPTHR31658 PTHR31658, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E9PBL8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XATAATSPAL KRLDLRDPAA LFETHGAEEI RGLERQVRAE IEHKKEELRQ
60 70 80 90 100
MVGERYRDLI EAADTIGQMR RCAVGLVDAV KATDQYCARL RQAGSAAPRP
110 120 130 140 150
PRAQQPQQPS QEKFYSMAAQ IKLLLEIPEK IWSSMEASQC LHATQLYLLC
160 170 180 190 200
CHLHSLLQLD SSSSRYSPVL SRFPILIRQV AAASHFRSTI LHESKMLLKC
210 220 230 240 250
QGVSDQAVAE ALCSIMLLEE SSPRQALTDF LLARKATIQK LLNQPHHGAG
260 270 280 290 300
IKAQICSLVE LLATTLKQAH ALFYTLPEGL LPDPALPCGL LFSTLETITG
310 320 330 340 350
QHPAGKGTGV LQEEMKLCSW FKHLPASIVE FQPTLRTLAH PISQEYLKDT
360 370 380 390 400
LQKWIHMCNE DIKNGITNLL MYVKSMKGLA GIRDAMWELL TNESTNHSWD
410 420 430 440 450
VLCRRLLEKP LLFWEDMMQQ LFLDRLQTLT KEGFDSISSS SKELLVSALQ
460 470 480 490 500
ELESSTSNSP SNKHIHFEYN MSLFLWSESP NDLPSDAAWV SVANRGQFAS
510 520 530 540 550
SGLSMKAQAI SPCVQNFCSA LDSKLKVKLD DLLAYLPSDD SSLPKDVSPT
560 570 580 590 600
QAKSSAFDRY ADAGTVQEML RTQSVACIKH IVDCIRAELQ SIEEGVQGQQ
610 620 630 640 650
DALNSAKLHS VLFMARLCQS LGELCPHLKQ CILGKSESSE KPAREFRALR
660 670 680 690 700
KQGKVKTQEI IPTQAKWQEV KEVLLQQSVM GYQVWSSAVV KVLIHGFTQS
710 720 730 740 750
LLLDDAGSVL ATATSWDELE IQEEAESGSS VTSKIRLPAQ PSWYVQSFLF
760 770 780 790 800
SLCQEINRVG GHALPKVTLQ EMLKSCMVQV VAAYEKLSEE KQIKKEGAFP
810 820 830 840 850
VTQNRALQLL YDLRYLNIVL TAKGDEVKSG RSKPDSRIEK VTDHLEALID
860 870 880 890 900
PFDLDVFTPH LNSNLHRLVQ RTSVLFGLVT GTENQLAPRS STFNSQEPHN
910 920 930 940 950
ILPLASSQIR FGLLPLSMTS TRKAKSTRNI ETKAQVGAKS KRLIRGWVPT
960
SHRATHDQLP FK
Length:962
Mass (Da):107,270
Last modified:October 3, 2012 - v2
Checksum:i80EFEB3F8BFE3A08
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8WTW3COG1_HUMAN
Conserved oligomeric Golgi complex ...
COG1 KIAA1381, LDLB
980Annotation score:
J3KRP4J3KRP4_HUMAN
Conserved oligomeric Golgi complex ...
COG1
124Annotation score:
J3QKY9J3QKY9_HUMAN
Conserved oligomeric Golgi complex ...
COG1
102Annotation score:
A0A087WVI0A0A087WVI0_HUMAN
Conserved oligomeric Golgi complex ...
COG1
940Annotation score:
J3QLT5J3QLT5_HUMAN
Conserved oligomeric Golgi complex ...
COG1
126Annotation score:
J3KSY3J3KSY3_HUMAN
Conserved oligomeric Golgi complex ...
COG1
26Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097641 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000438720; ENSP00000400111; ENSG00000166685
UCSCiuc060jlo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097641 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PBL8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiE9PBL8, 2 interactors

Proteomic databases

EPDiE9PBL8
MaxQBiE9PBL8
PeptideAtlasiE9PBL8
PRIDEiE9PBL8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000438720; ENSP00000400111; ENSG00000166685
UCSCiuc060jlo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000166685.11
HGNCiHGNC:6545 COG1
OpenTargetsiENSG00000166685
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2033 Eukaryota
ENOG410XR7E LUCA
GeneTreeiENSGT00390000017136

Miscellaneous databases

ChiTaRSiCOG1 human

Gene expression databases

BgeeiENSG00000166685 Expressed in 196 organ(s), highest expression level in adenohypophysis
ExpressionAtlasiE9PBL8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR033370 COG1
PANTHERiPTHR31658 PTHR31658, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PBL8_HUMAN
AccessioniPrimary (citable) accession number: E9PBL8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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