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Protein
Submitted name:

Protein kinase C epsilon type

Gene

PRKCE

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiE9PBI2

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinase C epsilon typeImported
Gene namesi
Name:PRKCEImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000171132.13
HGNCiHGNC:9401 PRKCE

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000171132

PTM / Processingi

Proteomic databases

MaxQBiE9PBI2
PeptideAtlasiE9PBI2
PRIDEiE9PBI2

Expressioni

Gene expression databases

BgeeiENSG00000171132 Expressed in 179 organ(s), highest expression level in frontal cortex
ExpressionAtlasiE9PBI2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PBI2
SMRiE9PBI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini131 – 219Protein kinaseInterPro annotationAdd BLAST89

Phylogenomic databases

eggNOGiKOG0694 Eukaryota
ENOG410XNPH LUCA
GeneTreeiENSGT00930000150815

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

E9PBI2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNVHRRCETN VAPNCGVDAR GIAKVLADLG VTPDKITNSG QRRKKLIAGA
60 70 80 90 100
ESPQPASGSS PSEEDRSKSA PTSPCDQEIK ELENNIRKAL SFDNRGEEHR
110 120 130 140 150
AASSPDGQLM SPGENGEVRQ GQAKRLGLDE FNFIKVLGKG SFGKVMLAEL
160 170 180 190 200
KGKDEVYAVK VLKKDVILQD DDVDCTMTEK RILALARKHP YLTQLYCCFQ
210
TKGTGFSIQG CACEGMREL
Length:219
Mass (Da):23,900
Last modified:April 5, 2011 - v1
Checksum:iA8DF9BA2FD8EACA9
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q02156KPCE_HUMAN
Protein kinase C epsilon type
PRKCE PKCE
737Annotation score:
C9JR22C9JR22_HUMAN
Protein kinase C epsilon type
PRKCE
127Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC017006 Genomic DNA No translation available.
AC017078 Genomic DNA No translation available.
AC079892 Genomic DNA No translation available.
AC092600 Genomic DNA No translation available.
AC115109 Genomic DNA No translation available.
U51244 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000394874; ENSP00000378341; ENSG00000171132
UCSCiuc061iup.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC017006 Genomic DNA No translation available.
AC017078 Genomic DNA No translation available.
AC079892 Genomic DNA No translation available.
AC092600 Genomic DNA No translation available.
AC115109 Genomic DNA No translation available.
U51244 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PBI2
SMRiE9PBI2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PBI2
PeptideAtlasiE9PBI2
PRIDEiE9PBI2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000394874; ENSP00000378341; ENSG00000171132
UCSCiuc061iup.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000171132.13
HGNCiHGNC:9401 PRKCE
OpenTargetsiENSG00000171132
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0694 Eukaryota
ENOG410XNPH LUCA
GeneTreeiENSGT00930000150815

Enzyme and pathway databases

SignaLinkiE9PBI2

Miscellaneous databases

ChiTaRSiPRKCE human

Gene expression databases

BgeeiENSG00000171132 Expressed in 179 organ(s), highest expression level in frontal cortex
ExpressionAtlasiE9PBI2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PBI2_HUMAN
AccessioniPrimary (citable) accession number: E9PBI2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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