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Protein
Submitted name:

Regulator of G-protein-signaling 12

Gene

RGS12

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Regulator of G-protein-signaling 12Imported
Gene namesi
Name:RGS12Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000159788.18
HGNCiHGNC:9994 RGS12

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000159788

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PBG5
PRIDEiE9PBG5

Expressioni

Gene expression databases

BgeeiENSG00000159788 Expressed in 194 organ(s), highest expression level in testis
ExpressionAtlasiE9PBG5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PBG5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 99PDZInterPro annotationAdd BLAST78
Domaini228 – 340PIDInterPro annotationAdd BLAST113

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
GeneTreeiENSGT00760000119142

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
PfamiView protein in Pfam
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SM00462 PTB, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit
PS01179 PID, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

E9PBG5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFRAGEASKR PLPGPSPPRV RSVEVARGRA GYGFTLSGQA PCVLSCVMRG
60 70 80 90 100
SPADFVGLRA GDQILAVNEI NVKKASHEDV VKLIGKCSGV LHMVIAEGVG
110 120 130 140 150
RFESCSSDEE GGLYEGKGWL KPKLDSKALG INRAERVVEE MQSGGIFNMI
160 170 180 190 200
FENPSLCASN SEPLKLKQRS LSESAATRFD VGHESINNPN PNMLSKEEIS
210 220 230 240 250
KVIHDDSVFS IGLESHDDFA LDASILNVAM IVGYLGSIEL PSTSSNLESD
260 270 280 290 300
SLQAIRGCMR RLRAEQKIHS LVTMKIMHDC VQLSTDKAGV VAEYPAEKLA
310 320 330 340 350
FSAVCPDDRR FFGLVTMQTN DDGSLAQEEE GALRTSCHVF MVDPDLFNHK
360 370 380 390 400
IHQGIARRFG FECTADPDTN GCLEFPASSL PVLQFISVLY RDMGELIEGM
410 420 430 440 450
RARAFLDGDA DAHQNNSTSS NSDSGIGNFH QEEKSNRVLV VDLGGSSSRH
460 470 480 490 500
GPGGSAWDGV GGRGAQPWGA PWTGPFCPDP EGSPPFEAAH QTDRFWDLNK
510 520 530 540 550
HLGPASPVEV PPASLRSSVP PSKRGTVGAG CGFNQRWLPV HVLREWQCGH
560 570 580 590 600
TSDQDSYTDS TDGWSSINCG TLPPPMSKIP ADRYRVEGSF AQPPLNAPKR
610 620 630 640 650
EWSRKAFGMQ SIFGPHRNVR KTKEDKKGSK FGRGTGLTQP SQRTSARRSF
660
GRSKRFSITR SLDDLES
Length:667
Mass (Da):72,523
Last modified:April 5, 2011 - v1
Checksum:iEEF246E0038F6AAF
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O14924RGS12_HUMAN
Regulator of G-protein signaling 12
RGS12
1,447Annotation score:
A0A2R8YCJ1A0A2R8YCJ1_HUMAN
Regulator of G-protein-signaling 12
RGS12
79Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590235 Genomic DNA No translation available.
AL645949 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000514268; ENSP00000424251; ENSG00000159788
UCSCiuc062uuf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590235 Genomic DNA No translation available.
AL645949 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PBG5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE9PBG5
PRIDEiE9PBG5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000514268; ENSP00000424251; ENSG00000159788
UCSCiuc062uuf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000159788.18
HGNCiHGNC:9994 RGS12
OpenTargetsiENSG00000159788
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
GeneTreeiENSGT00760000119142

Miscellaneous databases

ChiTaRSiRGS12 human

Gene expression databases

BgeeiENSG00000159788 Expressed in 194 organ(s), highest expression level in testis
ExpressionAtlasiE9PBG5 baseline and differential

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
PfamiView protein in Pfam
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SM00462 PTB, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit
PS01179 PID, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PBG5_HUMAN
AccessioniPrimary (citable) accession number: E9PBG5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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