Epididymis tissue sperm binding protein Li 14m

Functionⁱ

GO - Molecular functionⁱ

acetyl-CoA C-acyltransferase activity Source: Ensembl
enoyl-CoA hydratase activity Source: Ensembl
fatty-acyl-CoA binding Source: Ensembl
long-chain-3-hydroxyacyl-CoA dehydrogenase activity Source: Ensembl
long-chain-enoyl-CoA hydratase activity Source: Ensembl
NAD binding Source: Ensembl
protein-containing complex binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

fatty acid beta-oxidation Source: Ensembl
response to drug Source: Ensembl
response to insulin Source: Ensembl

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Epididymis tissue sperm binding protein Li 14mImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000084754.10

EuPathDBⁱ

HostDB:ENSG00000084754.10

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	E9KL44

PRIDEⁱ

E9KL44

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000084754
ExpressionAtlasⁱ	E9KL44 baseline and differential
Genevisibleⁱ	E9KL44 HS

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	E9KL44, 1 interactor
Molecular INTeraction database More...MINTⁱ	E9KL44

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	E9KL44
SMRⁱ	E9KL44
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	364 – 541	3HCDH_NInterPro annotationAdd BLAST	178
Domainⁱ	544 – 639	3HCDHInterPro annotationAdd BLAST	96
Domainⁱ	676 – 754	3HCDHInterPro annotationAdd BLAST	79

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	113 – 133	Sequence analysisAdd BLAST		21

Sequence similaritiesⁱ

Belongs to the enoyl-CoA hydratase/isomerase family.UniRule annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG1683 Eukaryota COG1024 LUCA COG1250 LUCA
KEGG Orthology (KO) More...KOⁱ	K07515
OMAⁱ	PFRYMDT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02LF
PhylomeDBⁱ	E9KL44

Family and domain databases

InterProⁱ	View protein in InterPro IPR006180 3-OHacyl-CoA_DH_CS IPR006176 3-OHacyl-CoA_DH_NAD-bd IPR006108 3HC_DH_C IPR008927 6-PGluconate_DH-like_C_sf IPR029045 ClpP/crotonase-like_dom_sf IPR018376 Enoyl-CoA_hyd/isom_CS IPR001753 Enoyl-CoA_hydra/iso IPR012803 Fa_ox_alpha_mit IPR036291 NAD(P)-bd_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00725 3HCDH, 2 hits PF02737 3HCDH_N, 1 hit PF00378 ECH_1, 1 hit
SUPFAMⁱ	SSF48179 SSF48179, 2 hits SSF51735 SSF51735, 1 hit SSF52096 SSF52096, 1 hit
TIGRFAMsⁱ	TIGR02441 fa_ox_alpha_mit, 1 hit
PROSITEⁱ	View protein in PROSITE PS00067 3HCDH, 1 hit PS00166 ENOYL_COA_HYDRATASE, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

E9KL44-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVACRAIGIL SRFSAFRILR SRGYICRNFT GSSALLTRTH INYGVKGDVA 
        60         70         80         90        100
VVRINSPNSK VNTLSKELHS EFSEVMNEIW ASDQIRSAVL ISSKPGCFIA 
       110        120        130        140        150
GADINMLAAC KTLQEVTQLS QEAQRIVEKL EKSTKPIVAA INGSCLGGGL 
       160        170        180        190        200
EVAISCQYRI ATKDRKTVLG TPEVLLGALP GAGGTQRLPK MVGVPAALDM 
       210        220        230        240        250
MLTGRSIRAD RAKKMGLVDQ LVEPLGPGLK PPEERTIEYL EEVAITFAKG 
       260        270        280        290        300
LADKKISPKR DKGLVEKLTA YAMTIPFVRQ QVYKKVEEKV RKQTKGLYPA 
       310        320        330        340        350
PLKIIDVVKT GIEQGSDAGY LCESQKFGEL VMTKESKALM GLYHGQVLCK 
       360        370        380        390        400
KNKFGAPQKD VKHLAILGAG LMGAGIAQVS VDKGLKTILK DATLTALDRG 
       410        420        430        440        450
QQQVFKGLND KVKKKALTSF ERDSIFSNLT GQLDYQGFEK ADMVIEAVFE 
       460        470        480        490        500
DLSLKHRVLK EVEAVIPDHC IFASNTSALP ISEIAAVSKR PEKVIGMHYF 
       510        520        530        540        550
SPVDKMQLLE IITTEKTSKD TSASAVAVGL KQGKVIIVVK DGPGFYTTRC 
       560        570        580        590        600
LAPMMSEVIR ILQEGVDPKK LDSLTTSFGF PVGAATLVDE VGVDVAKHVA 
       610        620        630        640        650
EDLGKVFGER FGGGNPELLT QMVSKGFLGR KSGKGFYIYQ EGVKRKDLNS 
       660        670        680        690        700
DMDSILASLK LPPKSEVSSD EDIQFRLVTR FVNEAVMCLQ EGILATPAEG 
       710        720        730        740        750
DIGAVFGLGF PPCLGGPFRF VDLYGAQKIV DRLKKYEAAY GKQFTPCQLL 
       760 
ADHANSPNKK FYQ

Length:763

Mass (Da):83,000

Last modified:April 5, 2011 - v1

Checksum:ⁱ247FF7B4E48FB484

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	GU727642 mRNA Translation: ADU87643.1
NCBI Reference Sequences More...RefSeqⁱ	NP_000173.2, NM_000182.4
UniGeneⁱ	Hs.516032

Genome annotation databases

GeneIDⁱ	3030
KEGGⁱ	hsa:3030

Protein	Similar proteins		Species	Score	Length
E9KL44	Trifunctional enzyme subunit alpha, mitochondrial		HUMAN		763
cDNA FLJ53969, highly similar to Trifunctional enzyme subunit alpha, mitochondrial		HUMAN		573

Protein	Similar proteins		Species	Score	Length
E9KL44	Trifunctional enzyme subunit alpha, mitochondrial		HUMAN		763
UPI0004DFE0BC		URSMA		812
UPI00093CDCC4		great roundleaf bat		776
UPI0002C67AEE		southern white rhinoceros		764
UPI0007A6EF07		MINNA		764
+55

Protein	Similar proteins		Species	Score	Length
E9KL44	Trifunctional enzyme subunit alpha, mitochondrial		HUMAN		763
UPI0004DFE0BC		URSMA		812
UPI00093CDCC4		great roundleaf bat		776
UPI0007A6EF07		MINNA		764
UPI000D1800CC		DESRO		764
+189

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	GU727642 mRNA Translation: ADU87643.1
NCBI Reference Sequences More...RefSeqⁱ	NP_000173.2, NM_000182.4
UniGeneⁱ	Hs.516032

3D structure databases

ProteinModelPortalⁱ	E9KL44
SMRⁱ	E9KL44
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	E9KL44, 1 interactor
Molecular INTeraction database More...MINTⁱ	E9KL44

Proteomic databases

PRIDEⁱ	E9KL44

PRIDEⁱ

E9KL44

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	3030
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	3030
KEGGⁱ	hsa:3030

Organism-specific databases

CTDⁱ	3030
EuPathDBⁱ	HostDB:ENSG00000084754.10

Phylogenomic databases

eggNOGⁱ	KOG1683 Eukaryota COG1024 LUCA COG1250 LUCA
KEGG Orthology (KO) More...KOⁱ	K07515
OMAⁱ	PFRYMDT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02LF
PhylomeDBⁱ	E9KL44

Miscellaneous databases

GenomeRNAiⁱ	3030

GenomeRNAiⁱ

3030

Gene expression databases

Bgeeⁱ	ENSG00000084754
ExpressionAtlasⁱ	E9KL44 baseline and differential
Genevisibleⁱ	E9KL44 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR006180 3-OHacyl-CoA_DH_CS IPR006176 3-OHacyl-CoA_DH_NAD-bd IPR006108 3HC_DH_C IPR008927 6-PGluconate_DH-like_C_sf IPR029045 ClpP/crotonase-like_dom_sf IPR018376 Enoyl-CoA_hyd/isom_CS IPR001753 Enoyl-CoA_hydra/iso IPR012803 Fa_ox_alpha_mit IPR036291 NAD(P)-bd_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00725 3HCDH, 2 hits PF02737 3HCDH_N, 1 hit PF00378 ECH_1, 1 hit
SUPFAMⁱ	SSF48179 SSF48179, 2 hits SSF51735 SSF51735, 1 hit SSF52096 SSF52096, 1 hit
TIGRFAMsⁱ	TIGR02441 fa_ox_alpha_mit, 1 hit
PROSITEⁱ	View protein in PROSITE PS00067 3HCDH, 1 hit PS00166 ENOYL_COA_HYDRATASE, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E9KL44_HUMAN
Accessionⁱ	E9KL44Primary (citable) accession number: E9KL44
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 5, 2011
	Last sequence update:	April 5, 2011
	Last modified:	May 23, 2018
	This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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UniProtKB - E9KL44 (E9KL44_HUMAN)

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Epididymis tissue sperm binding protein Li 14m

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ