Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Epididymis secretory sperm binding protein Li 44a

Gene

SERPINA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Epididymis secretory sperm binding protein Li 44aImported
Submitted name:
Serpin peptidase inhibitor clade A member 1 isoform 1Imported
Gene namesi
Name:SERPINA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000197249.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501430330825 – 418Sequence analysisAdd BLAST394

Expressioni

Gene expression databases

BgeeiENSG00000197249 Expressed in 207 organ(s), highest expression level in liver
GenevisibleiE9KL23 HS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 415SERPINInterPro annotationAdd BLAST357

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
KOiK03984
OMAiFFLPDEG
OrthoDBiEOG091G0ION

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

E9KL23-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSSVSWGIL LLAGLCCLVP VSLAEDPQGD AAQKTDTSHH DQDHPTFNKI
60 70 80 90 100
TPNLAEFAFS LYRQLAHQSN STNIFFSPVS IATAFAMLSL GTKADTHDEI
110 120 130 140 150
LEGLNFNLTE IPEAQIHEGF QELLRTLNQP DSQLQLTTGN GLFLSEGLKL
160 170 180 190 200
VDKFLEDVKK LYHSEAFTVN FGDTEEAKKQ INDYVEKGTQ GKIVDLVKEL
210 220 230 240 250
DRDTVFALVN YIFFKGKWER PFEVKDTEEE DFHVDQVTTV KVPMMKRLGM
260 270 280 290 300
FNIQHCKKLS SWVLLMKYLG NATAIFFLPD EGKLQHLENE LTHDIITKFL
310 320 330 340 350
ENEDRRSASL HLPKLSITGT YDLKSVLGQL GITKVFSNGA DLSGVTEEAP
360 370 380 390 400
LKLSKAVHKA VLTIDEKGTE AAGAMFLEAI PMSIPPEVKF NKPFVFLMIE
410
QNTKSPLFMG KVVNPTQK
Length:418
Mass (Da):46,737
Last modified:April 5, 2011 - v1
Checksum:i7016555F273B7F16
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei418Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU727620 mRNA Translation: ADU87622.1
KU178257 mRNA Translation: ALQ33715.1
RefSeqiNP_000286.3, NM_000295.4
NP_001002235.1, NM_001002235.2
NP_001002236.1, NM_001002236.2
NP_001121172.1, NM_001127700.1
NP_001121173.1, NM_001127701.1
NP_001121174.1, NM_001127702.1
NP_001121175.1, NM_001127703.1
NP_001121176.1, NM_001127704.1
NP_001121177.1, NM_001127705.1
NP_001121178.1, NM_001127706.1
NP_001121179.1, NM_001127707.1
XP_016876859.1, XM_017021370.1
UniGeneiHs.525557

Genome annotation databases

GeneIDi5265
KEGGihsa:5265

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU727620 mRNA Translation: ADU87622.1
KU178257 mRNA Translation: ALQ33715.1
RefSeqiNP_000286.3, NM_000295.4
NP_001002235.1, NM_001002235.2
NP_001002236.1, NM_001002236.2
NP_001121172.1, NM_001127700.1
NP_001121173.1, NM_001127701.1
NP_001121174.1, NM_001127702.1
NP_001121175.1, NM_001127703.1
NP_001121176.1, NM_001127704.1
NP_001121177.1, NM_001127705.1
NP_001121178.1, NM_001127706.1
NP_001121179.1, NM_001127707.1
XP_016876859.1, XM_017021370.1
UniGeneiHs.525557

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi5265
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5265
KEGGihsa:5265

Organism-specific databases

CTDi5265
EuPathDBiHostDB:ENSG00000197249.12

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
KOiK03984
OMAiFFLPDEG
OrthoDBiEOG091G0ION

Miscellaneous databases

ChiTaRSiSERPINA1 human
GenomeRNAii5265

Gene expression databases

BgeeiENSG00000197249 Expressed in 207 organ(s), highest expression level in liver
GenevisibleiE9KL23 HS

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9KL23_HUMAN
AccessioniPrimary (citable) accession number: E9KL23
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 10, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again