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Protein

Caveolin

Gene

DAPPUDRAFT_302366

Organism
Daphnia pulex (Water flea)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.UniRule annotation

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
CaveolinUniRule annotation
Gene namesi
ORF Names:DAPPUDRAFT_302366Imported
OrganismiDaphnia pulex (Water flea)Imported
Taxonomic identifieri6669 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaBranchiopodaDiplostracaCladoceraAnomopodaDaphniidaeDaphnia
Proteomesi
  • UP000000305 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei162 – 182HelicalSequence analysisAdd BLAST21
Transmembranei188 – 208HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Golgi apparatusUniRule annotationSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi6669.DappuP302366

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili76 – 97Sequence analysisAdd BLAST22

Sequence similaritiesi

Belongs to the caveolin family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IV7A Eukaryota
ENOG4111HJR LUCA
InParanoidiE9GCW9
KOiK06278
OMAiKICRIWQ
PhylomeDBiE9GCW9

Family and domain databases

InterProiView protein in InterPro
IPR001612 Caveolin
PANTHERiPTHR10844 PTHR10844, 1 hit
PfamiView protein in Pfam
PF01146 Caveolin, 1 hit

Sequencei

Sequence statusi: Complete.

E9GCW9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAETKSTSRA GSKLNLNEST MPLLDDEAHE KAETPEKDVI EMKEKASTTS
60 70 80 90 100
EGEKDDSNPE KIEEEKKDGD EEGGDKKKKK KEKKEKKEKK EKKEKTASCH
110 120 130 140 150
RRTQSCVQTF TVGLNVLDRD EKHINDTINL NFEDVLAEPD VAHGFDPIWR
160 170 180 190 200
AAFILFTGSR FWIYRLLSAI LALPLALVWG ITFSLITFFS VWLATPLLRI
210 220 230 240
MDVFLFYIRR VWVALVQTTL EPVANAVGGC FSNVKLTHNN QLQTV
Length:245
Mass (Da):27,847
Last modified:April 5, 2011 - v1
Checksum:i82BE7FB27C5923B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL732539 Genomic DNA Translation: EFX82628.1

Genome annotation databases

EnsemblMetazoaiEFX82628; EFX82628; DAPPUDRAFT_302366
KEGGidpx:DAPPUDRAFT_302366

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL732539 Genomic DNA Translation: EFX82628.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6669.DappuP302366

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiEFX82628; EFX82628; DAPPUDRAFT_302366
KEGGidpx:DAPPUDRAFT_302366

Phylogenomic databases

eggNOGiENOG410IV7A Eukaryota
ENOG4111HJR LUCA
InParanoidiE9GCW9
KOiK06278
OMAiKICRIWQ
PhylomeDBiE9GCW9

Family and domain databases

InterProiView protein in InterPro
IPR001612 Caveolin
PANTHERiPTHR10844 PTHR10844, 1 hit
PfamiView protein in Pfam
PF01146 Caveolin, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9GCW9_DAPPU
AccessioniPrimary (citable) accession number: E9GCW9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: December 20, 2017
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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