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Entry version 34 (12 Aug 2020)
Sequence version 1 (05 Apr 2011)
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Protein

FIP-RBD domain-containing protein

Gene

DAPPUDRAFT_310514

Organism
Daphnia pulex (Water flea)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • Rab GTPase binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transportARBA annotation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FIP-RBD domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:DAPPUDRAFT_310514Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDaphnia pulex (Water flea)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6669 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaBranchiopodaDiplostracaCladoceraAnomopodaDaphniidaeDaphnia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000305 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

EndosomeARBA annotation, MembraneARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6669.EFX89437

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini994 – 1056FIP-RBDInterPro annotationAdd BLAST63

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni179 – 228DisorderedSequence analysisAdd BLAST50
Regioni363 – 386DisorderedSequence analysisAdd BLAST24
Regioni426 – 456DisorderedSequence analysisAdd BLAST31
Regioni710 – 736DisorderedSequence analysisAdd BLAST27
Regioni770 – 793DisorderedSequence analysisAdd BLAST24
Regioni931 – 968DisorderedSequence analysisAdd BLAST38
Regioni983 – 1009DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi189 – 204PolyampholyteSequence analysisAdd BLAST16
Compositional biasi988 – 1009PolyampholyteSequence analysisAdd BLAST22

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRGF, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_288740_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9FTW4

KEGG Orthology (KO)

More...
KOi
K12484

Database of Orthologous Groups

More...
OrthoDBi
567750at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR037245, FIP-RBD_C_sf
IPR037789, FIP_classI
IPR019018, Rab-bd_FIP-RBD

The PANTHER Classification System

More...
PANTHERi
PTHR15746, PTHR15746, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 1 hit
PF09457, RBD-FIP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF144270, SSF144270, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51511, FIP_RBD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E9FTW4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWSPTHVQVT VCRVKGLLTK GKNGTNDAFV TISLGKEKFQ TSVKQKALSE
60 70 80 90 100
LEWQEECELA IPTQGNTAEI VLTALHQNFI GVDEFLGMVS LPLSNFDVYE
110 120 130 140 150
RPRTKWYPLK SKPGQEGKNK NRGEIEVRVA FTVKSGSLLD LSKKEKHKGS
160 170 180 190 200
FGHLSQAAHN IGGSLMSLGK EKKGGIKKLA SSVGSKLRLP KSGRDEKGGD
210 220 230 240 250
GRLSRHSSGR YSGKYSGGEP DPGVISEDDD EFRFDELSHK SSGSSLNLAG
260 270 280 290 300
GSSSLASGQG SLENLGGGEL LRHNSMKRSG SSATLPNRAI QPSTSISSLA
310 320 330 340 350
VSVTSGAMSE DPVVKEEKAG AAMTTAAMAT AAAAVLHASS PPSLVADGVP
360 370 380 390 400
SIIIQDSFVV EQPSLSPSAS PPSSKLNSGT VPVPKTRNAK NQEVPVEVDL
410 420 430 440 450
PAIIPQARQR KDLATVDEIP TMEVNSQPAG EEANAEFDTG QSLSARPRMS
460 470 480 490 500
ASPPHPSSFP VGVVMNDEHV ARPPPVPKPR RSPLPPTTSL EMLNEPSLPF
510 520 530 540 550
SDEFPIIQQQ PVVPPRNVID VKYSPSQISP IQLNPFDFES DDGQYSDSDV
560 570 580 590 600
YDQRFEDDDR GDILDLTYNP AQPSNVIVLG NVEESDEMML NEDSVCELLE
610 620 630 640 650
KVIQEHDHQT AGLPAEAPPP KPVRASNAVE LYNDETSEEE DEIPEEALPP
660 670 680 690 700
KSVRVFNAVE LYNGETSEEE DKILEESIEG EPTVNFFNDD FFNDQTVQIS
710 720 730 740 750
PVEKVEEEMV RVAPHQTSGR VEETPTNSSP KEIRRDRLFS LFSTPTSETD
760 770 780 790 800
TEPKSAGVVD LDWLDDSKED ISQGFGGSEH LSDGMTAASN SDHAKTMDSA
810 820 830 840 850
VYVTGEDNQA PEVSPSNSST STNFTEALSR PLSALLLAHE ADFTPPPATP
860 870 880 890 900
QLLKPAAVQT PLSVQSTASN GARQAELSWD NYDMAKWQTP DAGTGGAGGR
910 920 930 940 950
RSIVPFEPVD EEAKARRKRI SLAPCLKTMA LESPSCEQSA GSPITEDDED
960 970 980 990 1000
DDGAGEQAVS ANSNESHRMK MAASFHQRVV VGEDKPANNN TPRDHHRTPR
1010 1020 1030 1040 1050
DSSTSEDRLR VYQEKSREGL IGLLEDRDNE ISDLKDYIDS LLLKVIDTCP
1060
TVLQTPVKAK TSRK
Length:1,064
Mass (Da):115,109
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i51869B0C405C86A6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GL732524 Genomic DNA Translation: EFX89437.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
EFX89437; EFX89437; DAPPUDRAFT_310514

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dpx:DAPPUDRAFT_310514

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL732524 Genomic DNA Translation: EFX89437.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi6669.EFX89437

Genome annotation databases

EnsemblMetazoaiEFX89437; EFX89437; DAPPUDRAFT_310514
KEGGidpx:DAPPUDRAFT_310514

Phylogenomic databases

eggNOGiENOG502QRGF, Eukaryota
HOGENOMiCLU_288740_0_0_1
InParanoidiE9FTW4
KOiK12484
OrthoDBi567750at2759

Family and domain databases

Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR037245, FIP-RBD_C_sf
IPR037789, FIP_classI
IPR019018, Rab-bd_FIP-RBD
PANTHERiPTHR15746, PTHR15746, 1 hit
PfamiView protein in Pfam
PF00168, C2, 1 hit
PF09457, RBD-FIP, 1 hit
SMARTiView protein in SMART
SM00239, C2, 1 hit
SUPFAMiSSF144270, SSF144270, 1 hit
PROSITEiView protein in PROSITE
PS51511, FIP_RBD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9FTW4_DAPPU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9FTW4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: August 12, 2020
This is version 34 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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