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UniProtKB - E9BG25 (E9BG25_LEIDB)
Protein
Submitted name:
Peroxidoxin
Gene
LDBPK_230050
Organism
Leishmania donovani (strain BPK282A1)
Status
Functioni
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.
UniRule annotationSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 81 | Cysteine sulfenic acid (-SOH) intermediateUniRule annotation | 1 |
GO - Molecular functioni
- peroxidase activity Source: UniProtKB-UniRule
- peroxiredoxin activity Source: InterPro
Keywordsi
Molecular function | AntioxidantUniRule annotation, Oxidoreductase, PeroxidaseUniRule annotation |
Protein family/group databases
PeroxiBasei | 11259, Ldon2CysPrx |
Names & Taxonomyi
Protein namesi | Submitted name: PeroxidoxinImported |
Gene namesi | ORF Names:LDBPK_230050Imported |
Organismi | Leishmania donovani (strain BPK282A1)Imported |
Taxonomic identifieri | 981087 [NCBI] |
Taxonomic lineagei | Eukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | TriTrypDB:LdBPK_230050.1 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 36 – 194 | ThioredoxinInterPro annotationAdd BLAST | 159 |
Sequence similaritiesi
Belongs to the peroxiredoxin family.UniRule annotation
Keywords - Domaini
Redox-active centerUniRule annotationPhylogenomic databases
OMAi | FWYPKDF |
PhylomeDBi | E9BG25 |
Family and domain databases
InterProi | View protein in InterPro IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
E9BG25-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRRLPTSCF LKRSQFRGFA ATSPLLNLDY QMYRTATVRE AAPQFSGQAV
60 70 80 90 100
VNGAIKEINM NDYKGKYIVL FFYPMDFTFV CPTEIIAFSD RHADFEKLNT
110 120 130 140 150
QVVAVSCDSV YSHLAWVNTP RKKGGLGEMH IPVLADKSME IARDYGVLIE
160 170 180 190 200
ESGIALRGLF IIDKKGILRH STINDLPVGR NVDEALRVLE AFQYADENGD
210 220
AIPCGWKPGQ PTLDTTKAGE FFEKNM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FR799610 Genomic DNA Translation: CBZ34201.1 |
RefSeqi | XP_003860906.1, XM_003860858.1 |
Genome annotation databases
EnsemblProtistsi | CBZ34201; CBZ34201; LDBPK_230050 |
GeneIDi | 13389630 |
KEGGi | ldo:LDBPK_230050 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FR799610 Genomic DNA Translation: CBZ34201.1 |
RefSeqi | XP_003860906.1, XM_003860858.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
PeroxiBasei | 11259, Ldon2CysPrx |
Genome annotation databases
EnsemblProtistsi | CBZ34201; CBZ34201; LDBPK_230050 |
GeneIDi | 13389630 |
KEGGi | ldo:LDBPK_230050 |
Organism-specific databases
VEuPathDBi | TriTrypDB:LdBPK_230050.1 |
Phylogenomic databases
OMAi | FWYPKDF |
PhylomeDBi | E9BG25 |
Family and domain databases
InterProi | View protein in InterPro IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | E9BG25_LEIDB | |
Accessioni | E9BG25Primary (citable) accession number: E9BG25 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 5, 2011 |
Last sequence update: | April 5, 2011 | |
Last modified: | January 19, 2022 | |
This is version 45 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |