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UniProtKB - E9AQK6 (E9AQK6_LEIMU)

Entry version 46 (19 Jan 2022)
Sequence version 1 (05 Apr 2011)
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Protein
Submitted name:

Putative fucose kinase

Gene

LMXM_16_0480

Organism
Leishmania mexicana (strain MHOM/GT/2001/U1103)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinaseImported, Transferase
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative fucose kinaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:LMXM_16_0480Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLeishmania mexicana (strain MHOM/GT/2001/U1103)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri929439 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007259 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		TriTrypDB:LmxM.16.0480

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini102 – 301FucokinaseInterPro annotationAdd BLAST200
Domaini960 – 1015GHMP_kinases_NInterPro annotationAdd BLAST56

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...OMAi		IPRNDWA

Database for complete collections of gene phylogenies

More...PhylomeDBi		E9AQK6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012887, Fucokinase
IPR001174, Galkinase
IPR036554, GHMP_kinase_C_sf
IPR006204, GHMP_kinase_N_dom
IPR020568, Ribosomal_S5_D2-typ_fold

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07959, Fucokinase, 1 hit
PF00288, GHMP_kinases_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00960, LMBPPROTEIN

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54211, SSF54211, 1 hit
SSF55060, SSF55060, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E9AQK6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNVSFLFSLP RTLAEYEGAR RLLADAGALS LGEHGAKGGV AVPRLFCGCD 
        60         70         80         90        100
PEDKPLGSGG GTVHLLHACY VDEQRHAPAP AKKSFLSWLR LADTDGRVIV 
       110        120        130        140        150
HAGGLSRRLP AYAAVGKALL PLPPCRWHRG SQLSRTLLST QVPMYREMVA 
       160        170        180        190        200
TAPAHLRTLI ACGDVCVDAR GALPSLAPFA ESDVLCFGIR ADAHVLPSHG 
       210        220        230        240        250
VLFTARERPL DLDYMLQKPS LAEVRRRVAG GRHSFLLDVG MWMLSDRAVE 
       260        270        280        290        300
VLARKCLGGA LDAEDATGGG RDGHRCTAVR TAYDLYSEFG SALGSHAPSA 
       310        320        330        340        350
DPEIAGLKAS VVELRDAEFL HYGTNRQLIS AAAALQRREA AAPSWWWGAP 
       360        370        380        390        400
FDGVLAPERG GGEEAGLRAA AADAPAGCAA EELDFAAGDA MPLLATPSSV 
       410        420        430        440        450
IVQNSVVLAP LDGSAAAAAA DAPAGAPLSP VRHLWVESSW VGARWALRDQ 
       460        470        480        490        500
HILTGIPRND WALALPPGAC VSVVPVLPAA LGGCGAGTAP HAARAYHMDD 
       510        520        530        540        550
AFRGDVRSGA TMYMGVRLHD WLSSRGFSVA ELYPAARAAG GGAAPPLDMY 
       560        570        580        590        600
EAALFPVCAT EQQLGDFLYV ATLPLEAATG GCAGVDAARL AAGQAVWRTQ 
       610        620        630        640        650
PRVSAMDLLR LTDVPAMLRN REYYERRMLT LMLALVAADP AAPCARSPVL 
       660        670        680        690        700
SGPMIALLQQ QFFLLDLNRV AQRVVELGVP LPWRSGLTGW CCGVDAAGSA 
       710        720        730        740        750
GALSREAAPF AKGAAATAAS LARMFADEGS VSGGGRGAPL CTVPGRIVVA 
       760        770        780        790        800
HYHAFASRLM ELALEAMDTA EPPVSAPEKA RRLALLRAPS VEEARSLAAV 
       810        820        830        840        850
HDAAALAELR AAIMDSFPDE RHDPEMGVHL DQIIWGRCPI RIDVAGAWTD 
       860        870        880        890        900
TPPYTILSGG SVINVAVELN GQPPVQVYVR VREDPMIVMR SIDSGEQLSV 
       910        920        930        940        950
SSFDEIRTYA TMQNPFSIPK AALALCGFLP EFCATEYATL REQLAARFGG 
       960        970        980        990       1000
HGLEISLFVA IPTGSGLGTS SIVAGTVLRS LAEFCKLPWD NHDVCRRVLL 
      1010       1020       1030       1040       1050
IEQMLTAGGG WQDQYGGLFE GLKLVQCVPG LPCLPTVRWM PDSVYTDPRF 
      1060       1070       1080       1090       1100
AACHLLYYTG ITRMAKGILG EIVRDVFLNR GATLQLLREM GGPTTAAMYD 
      1110       1120       1130       1140       1150
AMTTGNYKGY ARLVQRTWEQ KKRLDDGVCN PAVQSIVDVV EPYVWGVTLP 
      1160       1170       1180       1190       1200
GAGGGGYMYM CAKDEACARR IRELLTANPP NGNARFVEMS VSASGLQISR 

S
Length:1,201
Mass (Da):127,647
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC41DC11A24539168
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
FR799569 Genomic DNA Translation: CBZ25225.1

NCBI Reference Sequences

More...RefSeqi		XP_003873733.1, XM_003873684.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		13450329

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		lmi:LMXM_16_0480

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR799569 Genomic DNA Translation: CBZ25225.1
RefSeqiXP_003873733.1, XM_003873684.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi13450329
KEGGilmi:LMXM_16_0480

Organism-specific databases

VEuPathDBiTriTrypDB:LmxM.16.0480

Phylogenomic databases

OMAiIPRNDWA
PhylomeDBiE9AQK6

Family and domain databases

InterProiView protein in InterPro
IPR012887, Fucokinase
IPR001174, Galkinase
IPR036554, GHMP_kinase_C_sf
IPR006204, GHMP_kinase_N_dom
IPR020568, Ribosomal_S5_D2-typ_fold
PfamiView protein in Pfam
PF07959, Fucokinase, 1 hit
PF00288, GHMP_kinases_N, 1 hit
PRINTSiPR00960, LMBPPROTEIN
SUPFAMiSSF54211, SSF54211, 1 hit
SSF55060, SSF55060, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9AQK6_LEIMU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9AQK6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: January 19, 2022
This is version 46 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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