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UniProtKB - E7FGA4 (E7FGA4_DANRE)

Entry version 81 (07 Oct 2020)
Sequence version 2 (20 Jan 2016)
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Protein
Submitted name:

Neuregulin 2

Gene

nrg2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGrowth factorARBA annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DRE-1227986, Signaling by ERBB2
R-DRE-1236394, Signaling by ERBB4
R-DRE-1250196, SHC1 events in ERBB2 signaling
R-DRE-1250342, PI3K events in ERBB4 signaling
R-DRE-1250347, SHC1 events in ERBB4 signaling
R-DRE-1257604, PIP3 activates AKT signaling
R-DRE-1306955, GRB7 events in ERBB2 signaling
R-DRE-1358803, Downregulation of ERBB2:ERBB3 signaling
R-DRE-1963640, GRB2 events in ERBB2 signaling
R-DRE-1963642, PI3K events in ERBB2 signaling
R-DRE-5673001, RAF/MAP kinase cascade
R-DRE-6785631, ERBB2 Regulates Cell Motility
R-DRE-6811558, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-DRE-8847993, ERBB2 Activates PTK6 Signaling
R-DRE-8863795, Downregulation of ERBB2 signaling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Neuregulin 2Imported
Submitted name:
Neuregulin 2bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nrg2bImported
Synonyms:NRG2bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Zebrafish Information Network genome database

More...ZFINi		ZDB-GENE-090205-2, nrg2b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei309 – 331HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501509032520 – 705Sequence analysisAdd BLAST686

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi254 ↔ 271PROSITE-ProRule annotation
Disulfide bondi273 ↔ 282PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSDARG00000086585, Expressed in brain and 17 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		7955.ENSDARP00000108874

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini141 – 228Ig-likeInterPro annotationAdd BLAST88
Domaini242 – 283EGF-likeInterPro annotationAdd BLAST42

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni392 – 432DisorderedSequence analysisAdd BLAST41
Regioni590 – 705DisorderedSequence analysisAdd BLAST116

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi392 – 412PolarSequence analysisAdd BLAST21
Compositional biasi415 – 431PolyampholyteSequence analysisAdd BLAST17
Compositional biasi651 – 698PolarSequence analysisAdd BLAST48

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the neuregulin family.ARBA annotation

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationARBA annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QRNM, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158778

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_023628_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		E7FGA4

Identification of Orthologs from Complete Genome Data

More...OMAi		YHREDDQ

Database of Orthologous Groups

More...OrthoDBi		313400at2759

TreeFam database of animal gene trees

More...TreeFami		TF332469

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000742, EGF-like_dom
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR040180, Neuregulin
IPR002154, Neuregulin_C

The PANTHER Classification System

More...PANTHERi		PTHR11100, PTHR11100, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07679, I-set, 1 hit
PF02158, Neuregulin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00409, IG, 1 hit
SM00408, IGc2, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726, SSF48726, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00022, EGF_1, 1 hit
PS50026, EGF_3, 1 hit
PS50835, IG_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E7FGA4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRLDPVHFS MLVIGVSFAC YAPSLDSLQD QAYRSAVVIE GKVSSLPENV 
        60         70         80         90        100
SVEPYSVNVT VLYVWPVNSG GLRREQLVTV GEFGSEAPCV AVEKHHTYIF 
       110        120        130        140        150
FMDPTEEPLV FKASFAPLDS TEKTLKKDVE SVLCKDCASA PKVKPMDSQW 
       160        170        180        190        200
LQEGKKLTLK CEAVGNPSPS FNWYKDGSQL RQKKTVKIKT NKKNSKLHIS 
       210        220        230        240        250
KVRLEDSGNY TCVVENSLGR ENATSFVSVQ SITTTLSPGS SHARKCNETE 
       260        270        280        290        300
KTYCINGGDC YFIHGINQLS CKCPNDYTGE RCQTSVMAGF YKHLGIEIME 
       310        320        330        340        350
AEELYQKRVL TITGICVALL VVGIVCVVAY CKTKKQRKKM HNHLHQNMCA 
       360        370        380        390        400
EHPNRMLANG PNHPGPGPEE IPMVDYISKN VPATERVVRH GTETSGNFSG 
       410        420        430        440        450
SRMSSRSHHT STASHTSSHR HEERTWSMER TDSIHSDCQS GALSSSVGTS 
       460        470        480        490        500
KCSSPACMEA RARRAAYCGY PDATQCSLQY GDSYDSLRDS PHSDRYVSAL 
       510        520        530        540        550
TTPARLSPVD FHSSLPPQVP TFQITTPNAS HALSLPPAAS AIAMAAYSPD 
       560        570        580        590        600
DDQPLLYRYR RSRRPYYAAE STGSLPSSPY RFVDDEDYET TQEYMSSREQ 
       610        620        630        640        650
PKKSSGSRRW RRRSRINGHT PGPRNYSSQS CLSDSEWEDE EVGDLGHGES 
       660        670        680        690        700
TPFLSMQNMN ATEPATIYRP NDTRTFSNTG RSGSRPNVQA NKLTQSRFRP 

DNAPL
Length:705
Mass (Da):78,341
Last modified:January 20, 2016 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD6BEBC60DDB6C192
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1QFX4F1QFX4_DANRE
Neuregulin 2b
nrg2b
599Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0R4INJ1A0A0R4INJ1_DANRE
Neuregulin 2b
nrg2b
176Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0R4IW84A0A0R4IW84_DANRE
Neuregulin 2b
nrg2b
138Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BX005008 Genomic DNA No translation available.
BX323592 Genomic DNA No translation available.
CR407701 Genomic DNA No translation available.
KT023305 mRNA Translation: AKS25897.1

NCBI Reference Sequences

More...RefSeqi		XP_005157176.1, XM_005157119.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSDART00000129055; ENSDARP00000108874; ENSDARG00000086585

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100270726

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX005008 Genomic DNA No translation available.
BX323592 Genomic DNA No translation available.
CR407701 Genomic DNA No translation available.
KT023305 mRNA Translation: AKS25897.1
RefSeqiXP_005157176.1, XM_005157119.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000108874

Genome annotation databases

EnsembliENSDART00000129055; ENSDARP00000108874; ENSDARG00000086585
GeneIDi100270726

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		100270726
ZFINiZDB-GENE-090205-2, nrg2b

Phylogenomic databases

eggNOGiENOG502QRNM, Eukaryota
GeneTreeiENSGT00940000158778
HOGENOMiCLU_023628_0_0_1
InParanoidiE7FGA4
OMAiYHREDDQ
OrthoDBi313400at2759
TreeFamiTF332469

Enzyme and pathway databases

ReactomeiR-DRE-1227986, Signaling by ERBB2
R-DRE-1236394, Signaling by ERBB4
R-DRE-1250196, SHC1 events in ERBB2 signaling
R-DRE-1250342, PI3K events in ERBB4 signaling
R-DRE-1250347, SHC1 events in ERBB4 signaling
R-DRE-1257604, PIP3 activates AKT signaling
R-DRE-1306955, GRB7 events in ERBB2 signaling
R-DRE-1358803, Downregulation of ERBB2:ERBB3 signaling
R-DRE-1963640, GRB2 events in ERBB2 signaling
R-DRE-1963642, PI3K events in ERBB2 signaling
R-DRE-5673001, RAF/MAP kinase cascade
R-DRE-6785631, ERBB2 Regulates Cell Motility
R-DRE-6811558, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-DRE-8847993, ERBB2 Activates PTK6 Signaling
R-DRE-8863795, Downregulation of ERBB2 signaling

Gene expression databases

BgeeiENSDARG00000086585, Expressed in brain and 17 other tissues

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR000742, EGF-like_dom
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR040180, Neuregulin
IPR002154, Neuregulin_C
PANTHERiPTHR11100, PTHR11100, 1 hit
PfamiView protein in Pfam
PF07679, I-set, 1 hit
PF02158, Neuregulin, 1 hit
SMARTiView protein in SMART
SM00409, IG, 1 hit
SM00408, IGc2, 1 hit
SUPFAMiSSF48726, SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS00022, EGF_1, 1 hit
PS50026, EGF_3, 1 hit
PS50835, IG_LIKE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7FGA4_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7FGA4
Secondary accession number(s): A0A0K0WSF9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: January 20, 2016
Last modified: October 7, 2020
This is version 81 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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