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Entry version 69 (31 Jul 2019)
Sequence version 1 (08 Mar 2011)
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Protein
Submitted name:

Neurofibromin 1b

Gene

nf1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Neurofibromin 1bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nf1bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-091111-4 nf1b

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E7FFY1

PeptideAtlas

More...
PeptideAtlasi
E7FFY1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000004184 Expressed in 20 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000119608

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1150 – 1366Ras-GAPInterPro annotationAdd BLAST217
Domaini1495 – 1653CRAL-TRIOInterPro annotationAdd BLAST159

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2706 – 2759DisorderedSequence analysisAdd BLAST54

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili969 – 989Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2735 – 2751PolarSequence analysisAdd BLAST17

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1826 Eukaryota
ENOG410XRPJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000074797

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E7FFY1

KEGG Orthology (KO)

More...
KOi
K08052

Identification of Orthologs from Complete Genome Data

More...
OMAi
NERAIRP

Database of Orthologous Groups

More...
OrthoDBi
9686at2759

TreeFam database of animal gene trees

More...
TreeFami
TF300302

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00170 SEC14, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit
3.40.525.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR011993 PH-like_dom_sf
IPR039360 Ras_GTPase
IPR023152 RasGAP_CS
IPR001936 RasGAP_dom
IPR008936 Rho_GTPase_activation_prot

The PANTHER Classification System

More...
PANTHERi
PTHR10194 PTHR10194, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13716 CRAL_TRIO_2, 1 hit
PF00616 RasGAP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00323 RasGAP, 1 hit
SM00516 SEC14, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48350 SSF48350, 1 hit
SSF48371 SSF48371, 1 hit
SSF52087 SSF52087, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
PS00509 RAS_GTPASE_ACTIV_1, 1 hit
PS50018 RAS_GTPASE_ACTIV_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E7FFY1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAQKPVEWV QAVISRFDEQ LPVKVGVQNT HTKISTEHNK ECLINISRYK
60 70 80 90 100
FSLVISGLTN ILKNVNNMRI FGDTAERNLY LSQLIILDTL EKCLAGQPKD
110 120 130 140 150
SMRLDETMLV KQLLPEICHF IHTYREGNQH AAELRSSACG VLFSLSCSNF
160 170 180 190 200
NAVFSRISTR LQELTVCSED TVDVHDIELI QYINVDGCKL KRLLQETVFK
210 220 230 240 250
FKALKKPAQL SVIFNLEKAF WNWVENYPDE FTRLYQRPQT DMADCAEKLF
260 270 280 290 300
DLVDSFAEST KRKAAVWPLQ IILLILCPDI TQDMSRDAAE DAKDNKKLFL
310 320 330 340 350
ENLRKALTGH GGSKQLTESA AIACVKLCKA STYISWEDHS VIFLLVQSIV
360 370 380 390 400
MDLKGLLFNP VKPFSRGAGS QSADLDLMID CFVSCFRINP HNNQQFKVCL
410 420 430 440 450
ASSSPSTFHF VLVNSLHRII TNSPLDWWPK IDTVYCYSGE LRLMFAETLG
460 470 480 490 500
RVVQGCSHTT LRLTPSLTFK EKMSSLKFKE KTTDLDTRSL KYLLLALVKL
510 520 530 540 550
IHADPKLMLH NPGKQGLEVH SSTAELITGL VQLVPLANMG EISQEAMEAL
560 570 580 590 600
LVLHQPESIE LWNPDAPMET FWDISSQVLY FICKNLFGHP LVSSTEILKW
610 620 630 640 650
LREILICRNK FLLRNKDRAT VGSNIATCRQ AQTKLEVCLY MFLWSPDMEA
660 670 680 690 700
VLVAMSCFRY LCEEAEIRCG VEDIPVQSLL PNYNTFMEFA SVSNMMVTGR
710 720 730 740 750
SALQKRVMAL LRKIELPTPG NTEAWEDTHA KWEHATKLIL SHPKTKLEDG
760 770 780 790 800
QEWINMTGFL CALGGVCLQQ RHVSALATYS PPMGTLNDRK GSMVSMSSCE
810 820 830 840 850
GSPETPLGRF LDRLLSLMVC SHEKGHQIRT NVKDLVGLEL SPVLYPMLFN
860 870 880 890 900
KLKNSISRFF DAQGPVPINE TNTQFVEQTI AIMKNLLDNH TEGSSEHLGQ
910 920 930 940 950
ASIETMMLNL VRYVRILGNM VHAIQIKTKL CQLVEVMMER RDDLSFCQEM
960 970 980 990 1000
KFRNKMVEYL TDWVMGTSNQ AADDDVKCLT RDLDQASMEA VVSLLAGLPL
1010 1020 1030 1040 1050
QPEEGDGVEL MEAKSQLFLK YFTLFMNLLN DCSEVEDEGQ PVVGRKRGMS
1060 1070 1080 1090 1100
RRLASLRHCT ILAMSNLLSA NVDSGLMHSI GLGYHKDLQT RATFMEVLTK
1110 1120 1130 1140 1150
ILQQGTEFDT LAETALADRF ERLVELVTMM GDQGELPIAM ALASVVPCSQ
1160 1170 1180 1190 1200
WDELARVLVT LFDSRHLLYQ LLWNMFSKEV ELADSMQTLF RGNSLASKIM
1210 1220 1230 1240 1250
TFCFKVYGAT YLQKLLEPLL RSVIAGTEWH MLSFEVDPTR LENGENLEEN
1260 1270 1280 1290 1300
QRNLLRMTER FFKAIISSSG EFPPQLRSVC HCLFQATCHS LLSKASVKDR
1310 1320 1330 1340 1350
KEVRKAVVSQ RFPQNSIGAV GSAMFLRFVN PAIVSPYEAG ILDKKPQPRI
1360 1370 1380 1390 1400
ERGLKLMSKI LQSIANHVLF TKEEHMRPFN DFVKSNFDAA RRFFLDIASD
1410 1420 1430 1440 1450
CPASDSLNHS LSFISDGNVL ALHRLLWNNQ EKIGQYLSSN RDHKAVGRRP
1460 1470 1480 1490 1500
FDKMATLLAY LGPPEHKPVA DTHWSSLNLT SSKFEEFMTR HQVHEKEEFK
1510 1520 1530 1540 1550
ALKTLHIFYQ AGTSKNGNPV FYYVTRRFKT GQINGDLLIY HVLLTLKPYY
1560 1570 1580 1590 1600
AKPYELVVDL THAGPSNRFK TDFLSKWFVV FPGFAYENVA AIYIYNCNTW
1610 1620 1630 1640 1650
VREYTKYHER LLTGLKGSKK LLFIDSPARL AEHVEPEQQK LPAATLALEE
1660 1670 1680 1690 1700
DLKVFHNALK LAHRDTKVSI KVGSTAVQVT SAERTRVLGQ SVFLNDIYYA
1710 1720 1730 1740 1750
SEIEEICLVD ENQFTLTIAN QGTPLTFMHQ ECESIVHSII HIRTRWELSQ
1760 1770 1780 1790 1800
PDSIPQHTKI RPKDVPGTLL NIALLNLGSS DPSLRSAAYN LLCALTCTFN
1810 1820 1830 1840 1850
LKIEGQLLET SGLCIPANNT LFIVSISQTL AANEPHLTLE FLEECISGFS
1860 1870 1880 1890 1900
KSSIELKHLC LEYMTPWLLN LVRFCKHSDD AKRQRVTAIL DKLITMTINE
1910 1920 1930 1940 1950
KQMYPSIQAK IWGSLGQITD LLDVVLDSFI KTSATGGLGS IKAEVMADTA
1960 1970 1980 1990 2000
VALASGNVKL VSSKVIIRMC KIIDKTCLSP TPTLEQHLMW DDIAILARYM
2010 2020 2030 2040 2050
LMLSFNNSLD VAAHLPYLFH VVTLLVATGP LSLRASTHGL VINIIHSLCT
2060 2070 2080 2090 2100
CSQLSFSEET KQVLRLSLTE FSLPKFYLLF GISKVKSAAV IAFRSSYRDR
2110 2120 2130 2140 2150
SFSPGSYERE TFALSSLETV TEALLEIMEA CMRDIPGCKW LDQWTDLAQK
2160 2170 2180 2190 2200
FAFQYNPSLQ PRALVVFGCI SKRVTHTQMK QIIRILSKAS LLLSIDRGLE
2210 2220 2230 2240 2250
SCLKGPDNCN SQVLIEATVI ALTKLQPLLN KDSAMHKALF WVAVAVLQLD
2260 2270 2280 2290 2300
EVNLYSAGTA LLEQNLHTLD SLRVFNDKSP EEVFMEIRQP LEWHCKQMDH
2310 2320 2330 2340 2350
FVGLNFNSNF NFALVGHLLK GFRHPSPTTV ARTIRILHML LALVGKHQNC
2360 2370 2380 2390 2400
DKFEVNTQSV AYLAALLPVS EEVRSRCSLK HRKLLLFSDV TMENVQMDPY
2410 2420 2430 2440 2450
SVHHEDPSGR TLRENELWAS PKVSERYLVA HFPIMGQISP RTRKSMSLDM
2460 2470 2480 2490 2500
GQPSQVNTKK LLGTRKSFDL LLSDSKAPKR PEIETGITTP PKMRRVAENE
2510 2520 2530 2540 2550
YEIETPRISH HHLRKVSVSE SNVLLNEEVL TDPKIQALLL TVLATQVKNT
2560 2570 2580 2590 2600
SDEFEQRILY EFLAEASVVF PKVFPVVHNL LDSKINTLLS LCQDPHLLNP
2610 2620 2630 2640 2650
VHGIVQSVVY HEESPPQYQP SYLQTFGFNG LWRFAGPFSK QTQFPDYAEL
2660 2670 2680 2690 2700
IVKFLDALID TYLPGIDEET SEEGLRTPTS PYPPPVQSQL SITANLNLSN
2710 2720 2730 2740 2750
SMTSLATSQH APGMDKEKVD LSPTTGLAAG GRTRHGSASQ VQKQRSTGSF

KRPSIKKIV
Length:2,759
Mass (Da):311,294
Last modified:March 8, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1E7E9256CCBB5EB5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CT573181 Genomic DNA No translation available.
CT573231 Genomic DNA No translation available.
CU459057 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_005169246.1, XM_005169189.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000131897; ENSDARP00000119608; ENSDARG00000004184

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
564518

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:564518

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573181 Genomic DNA No translation available.
CT573231 Genomic DNA No translation available.
CU459057 Genomic DNA No translation available.
RefSeqiXP_005169246.1, XM_005169189.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000119608

Proteomic databases

PaxDbiE7FFY1
PeptideAtlasiE7FFY1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000131897; ENSDARP00000119608; ENSDARG00000004184
GeneIDi564518
KEGGidre:564518

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
564518
ZFINiZDB-GENE-091111-4 nf1b

Phylogenomic databases

eggNOGiKOG1826 Eukaryota
ENOG410XRPJ LUCA
GeneTreeiENSGT00550000074797
InParanoidiE7FFY1
KOiK08052
OMAiNERAIRP
OrthoDBi9686at2759
TreeFamiTF300302

Gene expression databases

BgeeiENSDARG00000004184 Expressed in 20 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd00170 SEC14, 1 hit
Gene3Di2.30.29.30, 1 hit
3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR011993 PH-like_dom_sf
IPR039360 Ras_GTPase
IPR023152 RasGAP_CS
IPR001936 RasGAP_dom
IPR008936 Rho_GTPase_activation_prot
PANTHERiPTHR10194 PTHR10194, 1 hit
PfamiView protein in Pfam
PF13716 CRAL_TRIO_2, 1 hit
PF00616 RasGAP, 1 hit
SMARTiView protein in SMART
SM00323 RasGAP, 1 hit
SM00516 SEC14, 1 hit
SUPFAMiSSF48350 SSF48350, 1 hit
SSF48371 SSF48371, 1 hit
SSF52087 SSF52087, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
PS00509 RAS_GTPASE_ACTIV_1, 1 hit
PS50018 RAS_GTPASE_ACTIV_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7FFY1_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7FFY1
Secondary accession number(s): E9QE85
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 31, 2019
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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