Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 63 (07 Oct 2020)
Sequence version 1 (08 Mar 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Apolipoprotein Ba

Gene

apoba

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransportARBA annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-3000471, Scavenging by Class B Receptors
R-DRE-3000480, Scavenging by Class A Receptors
R-DRE-3000497, Scavenging by Class H Receptors
R-DRE-381426, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-DRE-432142, Platelet sensitization by LDL
R-DRE-5686938, Regulation of TLR by endogenous ligand
R-DRE-8856825, Cargo recognition for clathrin-mediated endocytosis
R-DRE-8856828, Clathrin-mediated endocytosis
R-DRE-8866423, VLDL assembly
R-DRE-8957275, Post-translational protein phosphorylation
R-DRE-8963888, Chylomicron assembly
R-DRE-8963901, Chylomicron remodeling
R-DRE-8964026, Chylomicron clearance
R-DRE-8964038, LDL clearance
R-DRE-8964041, LDL remodeling
R-DRE-975634, Retinoid metabolism and transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Apolipoprotein BaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:apobaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-070702-4, apoba

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500321936418 – 4418Sequence analysisAdd BLAST4401

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E7FBD3

PeptideAtlas

More...
PeptideAtlasi
E7FBD3

PRoteomics IDEntifications database

More...
PRIDEi
E7FBD3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000042780, Expressed in multi-cellular organism and 20 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000062792

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 650VitellogeninInterPro annotationAdd BLAST612

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili731 – 751Sequence analysisAdd BLAST21
Coiled coili2201 – 2231Sequence analysisAdd BLAST31
Coiled coili4241 – 4268Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4338, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00590000083139

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000127_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E7FBD3

Database of Orthologous Groups

More...
OrthoDBi
5350at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
E7FBD3

TreeFam database of animal gene trees

More...
TreeFami
TF331316

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.20, 1 hit
2.30.230.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015819, Lipid_transp_b-sht_shell
IPR001747, Lipid_transpt_N
IPR009454, Lipid_transpt_open_b-sht
IPR011030, Lipovitellin_superhlx_dom
IPR015816, Vitellinogen_b-sht_N
IPR015255, Vitellinogen_open_b-sht

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06448, DUF1081, 1 hit
PF09172, DUF1943, 1 hit
PF01347, Vitellogenin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01169, DUF1943, 1 hit
SM00638, LPD_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48431, SSF48431, 1 hit
SSF56968, SSF56968, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51211, VITELLOGENIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E7FBD3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDTKLCLLLF LSAHLLAGST EVAEEDTEGL SKCPLSARFK NLRKYVYQYT
60 70 80 90 100
AESKNGVTGT ANLKNGPKIS CQVEIEVPQT CSFVLRTTEC VLSEVSVIDA
110 120 130 140 150
QGQPVYRQAA GAEAFQAAME KNTLNFVVDQ VTSVSIYPEE DEPENILNIK
160 170 180 190 200
RGIISALLVP VLEEEHNERM STIHGICKTE VTVNSRKDID IDVSVVRDLS
210 220 230 240 250
DCSHFSPHSL STSPLSLMPG LNGLFSKLIR STQTCNYQFD NRRKHMTEAQ
260 270 280 290 300
CTEKHLFIPF SHEGQYGISS EVKQSLTLQD SVKINNRYFN KDDTLEKKLF
310 320 330 340 350
IEEVEDKHPV QSKDDVLATM KELITLSSSG KSQQRASLFH KLVSEVRGLK
360 370 380 390 400
NETLSGAADE MMKFSEWLTW QTLFQCGTDE CTSAIMQILR TFDEADREVD
410 420 430 440 450
AIVYALSLLP QSSPQRLRDM LSMAQSKPSK PIMYALANTV KQLPQDQATS
460 470 480 490 500
TPEVKEVAKF MEFMLGDCSG DEDSTFLTLR VIGVMGKYME GFPSLKSSVL
510 520 530 540 550
NCMKQAYAPL PVQKAAIQAF RLMEMDSDVR SALIQQYQNV EAPAQKRIAA
560 570 580 590 600
YLMLMRNPEV AENVLRTLKS EQNEQVKSFV SSHIANILES ENPNLSIAKD
610 620 630 640 650
YILKAVQGDV SFPPMDFTKL SRNYKTEVPL VGSVESNVIF DSANYMPREV
660 670 680 690 700
MLATTLDNFN PEILEIGLEG EGLEPVIEVL FGENGFFPDT ISKAMYWVND
710 720 730 740 750
KIPHPVKRVL EKWISPLNGE RMKRQVPQDI MKSMEEYISE FKNRLEQVED
760 770 780 790 800
APKGLAYLRL FGTELGYLKT SDLKHVTQYI NLCAETFKST SLNFMGKLIS
810 820 830 840 850
SLENEFFVHY MFLDKAFTLP TSAGFPLKLT LSGVLAPGAK GGLTIDRMMQ
860 870 880 890 900
QLSFMPSVGV EFITQMGVYI PEFVVAGIET HTNLYHESAV NARVTLSDSQ
910 920 930 940 950
IKLSIPAPSG NIQLFSVSNK ILSVTSTQTK IVPSMVEDRI DSTECNRIFP
960 970 980 990 1000
GMNYCTILRY SNASSTNNAP YYPLTGETRL ALELQPTGEV REYTATISYA
1010 1020 1030 1040 1050
LLREGKEGRQ KVDSVKIVLK AEGAEPTEAT AVVKYNRNRS ILTTDLQIPD
1060 1070 1080 1090 1100
YDLEAGIKLA VTDTNAKGKK MRGITIDVTN RDIPQLSIVG HARLESMRDG
1110 1120 1130 1140 1150
LIELQMSVPA LQMDTSATAT LKKNNGLVLQ LETAFNMPET TSVQKAILRY
1160 1170 1180 1190 1200
DNNKVEIEMK SDINSEVEKL FPNMEEYRSQ LQASIDEILD KKVTKTDMKL
1210 1220 1230 1240 1250
RHIVSKGLEA VNIWLDKIAA GSSFVDVQRN KRSTPELILP SLPEKLYLKS
1260 1270 1280 1290 1300
DALLRYQFNK GRISISLPLL LGGKSSAELD IPPTLTLPQI QIPLLGLEVP
1310 1320 1330 1340 1350
ENSYKIPTFT IPRTLEFSLP MLGVAELSAK MNSNFYEWEG SILGGNNTVD
1360 1370 1380 1390 1400
VPNYIAKYKI MASCPLTPLS YKIEGMGMIS GTVDDTLKYL VNGSINHCLL
1410 1420 1430 1440 1450
DASISFFETM SLADKINGRT NYRLEASSPL GLDTSLFYSA QSASTSDEVI
1460 1470 1480 1490 1500
GDGNLDGFIK IGSLYANSTL SQSYIYNMPK QEGKGESTLK FDSSLIQGQN
1510 1520 1530 1540 1550
VIKGSYVNGE LSLLSKTNAQ NDVLKHVVEL KHKKGELSVK SDGSATALGK
1560 1570 1580 1590 1600
ALRCKAELDV KNGEATLKVE SQANDATHDA FSLLTGSLNS NGLEINMEGL
1610 1620 1630 1640 1650
LNLESGRGTH KGTLSFGGNG LSTSCMTTIE GNSLTFENAF NGGINGEGAS
1660 1670 1680 1690 1700
VSVVSKGSSQ DNTIELSAKG KISPKEASLT SVFQGNAFDG TARNTMNIGI
1710 1720 1730 1740 1750
NKQGLSMSNT MRGTLQKMRS ECMQTLNITL WTLAFRSKMD NFICDGASYN
1760 1770 1780 1790 1800
HDIKVNMRPF ITSISANNEL ELFDFGLSSD GRLKMEPFKM DVAGSLSGKY
1810 1820 1830 1840 1850
GEDDSFNHGC EFTYADLAGT IKCDTAVKVF DSHISNRFDL DFAGLSSVMN
1860 1870 1880 1890 1900
TKTQVNCESL RLENNIRTMA MPFSLTVDAI LNSDGTVNFY GKHSGQVSSK
1910 1920 1930 1940 1950
FLLKAEPLAI AKSHECRASA VHMLPNGESA ETHIENKFDS LLIPNEQSVL
1960 1970 1980 1990 2000
WKFKSKLNNH AYNQDVNIYN KENDMGVQFS GVLQTNLFNT ERESSDIPLD
2010 2020 2030 2040 2050
NQKFSTSGFV KYDKNSDCHI IYFPFIESFP AAFESIKNAI LHKFESLQNY
2060 2070 2080 2090 2100
LNSLDLNALI GQFRNKLDEF PQKVNDIIVD LDLENKINNV KNQLISLIHD
2110 2120 2130 2140 2150
YTISIDDLDA YAERFKEATG KKIIDFATKI RDLSIQIKDG IESGAWANSV
2160 2170 2180 2190 2200
SDILAQIGRE LKAFDEQYKI TKTIIRGIDG IEDVIRQIDL EKLKDSSATW
2210 2220 2230 2240 2250
LKQLDAKYEI KTKLLEKLSE LRKVVETFEI NMLLEDLRQY ITSIDLTEYV
2260 2270 2280 2290 2300
DQLSGQIPYE DIERVLDSAK DVILNWIEEY EVPEKINRVY LNAQELILRY
2310 2320 2330 2340 2350
EIDKKIEVIV EQAIILVKQY RIQELVQAVV DTLKSIQFEY ISDKMMEIMD
2360 2370 2380 2390 2400
SIVSLLKRMD FQKIVNDLND YIQLIIKTFR TFDYNTYIDE VNRKVRDVVD
2410 2420 2430 2440 2450
YINKQINEVY EIPRKIEASR EFIKEMQATV FDYLEKLKNT RIAEVCRNIK
2460 2470 2480 2490 2500
DVIDTTAYKD IKLKIQDIIE DVRQRISDMD IRNEISVYLE RASGAYVNMI
2510 2520 2530 2540 2550
EYILTQFTQL IDEMKKMAED KEILDQISQA VEGVFNALKT AEFDVPAFML
2560 2570 2580 2590 2600
PFTTLEIPAF KIKMARIHDI TIPAMITIPE FTVLDLISLP SITVDFEKIK
2610 2620 2630 2640 2650
QSIIDFIDKV RQIEMPEVDP EAIFGDLRAL YLSDLPDFTF SEITLSEIKF
2660 2670 2680 2690 2700
PEINVPKLKL DSFEITMLPI PEVKFPEIPF EPCLPAFGKL YGEFKVDSPY
2710 2720 2730 2740 2750
YTLMTSAAFE NTTTALKFPQ FKATLKSNAK SSLEFLDYTL DAMLQIEAPK
2760 2770 2780 2790 2800
MRKMIISETV SLSHMAFGTE HEGSVVLSGP SAEATAKTAV KVTTHMYTAD
2810 2820 2830 2840 2850
LINNIGITLK NGISAYMDTS YNHNLNIPRL DISSQAIITR TAKARFESGT
2860 2870 2880 2890 2900
ISLTVGTVGS GKWSPSNPSR TVKSIDDYSD EITHKSDFEI TVNAGTAKLN
2910 2920 2930 2940 2950
FDGETNSRNL KMKQSVSAES VILSHITIDA RAETEAPFLK GSVLTLKVKA
2960 2970 2980 2990 3000
QMEDVRMEIE ISHSADLIGK VSGSISNTCD FLAQPFEVTL DCRNKGNSKI
3010 3020 3030 3040 3050
ILPLKLTGKI DLQDDFGFTL NSNKQHAFWV GLARFNQYKY KHNLTFDNNE
3060 3070 3080 3090 3100
NEAGIYTSVD CEANLEFLTV PISIPEIPIP YLGIKTPKIN EFSFWEDYRL
3110 3120 3130 3140 3150
KDLLTTPKQT IDIDFKLLYQ KNPEKHTFDL NLEPIYEAFN ENAKILRLHF
3160 3170 3180 3190 3200
ELGRDHIFDA LTNSYNQARI QHEKYKIDTS NHPPRYFTVP GYTIPILNIE
3210 3220 3230 3240 3250
VSAFRAELPA FGYFIPKEVS TPSFKTPLLG FSVPSYTLVL PSLALPVLHV
3260 3270 3280 3290 3300
PETLRDLTLP TFTIPDIQNN IMIPAFGNLT YEFSIKSPVL SLNSNGGLYN
3310 3320 3330 3340 3350
HSDMVIKFDV SSTSVFDVLK GKLDGSATIN KRRGLKMATS LSLVHMCAEC
3360 3370 3380 3390 3400
SHESTVSLTK RNMEASLTNL AKIKCPVLMM DLNQVLRGNT KSKPNIASNI
3410 3420 3430 3440 3450
KVSYSYDLPI IETQGTGSID HNFALEALSS YISLESAWKG TTDSTIMESG
3460 3470 3480 3490 3500
NLAASLNNEV TIYLNANGLR STLKTDVNSK VYHQKAGSWN IDVTKNLALE
3510 3520 3530 3540 3550
ASLRRIYATM AYTSSNAASI ASFSTNGKQN VRATLEFVPL TTLSANLDID
3560 3570 3580 3590 3600
ISQPTNYGHA GIVENIDLSI TSDKQRFLWS GKEQLATLIH SADLILSNTQ
3610 3620 3630 3640 3650
SEIRVEMSES VEGKVAFLKS IKLPVYQKSL WDIFKFGEVS STGELQFFNV
3660 3670 3680 3690 3700
STVVIYTKSM EGTLFAIPTK LFENGVSFNI PQITFGVPDL FKTIPQMIRE
3710 3720 3730 3740 3750
VDMRFEEPDL PDYISIPPVI TIPEFSIPFT TLHVPTFVID LTNLEVPNEI
3760 3770 3780 3790 3800
STPSFDIMLP GLPKVEIPSI NARTKYLKDK MAHLFVSLPQ YEITISPFNL
3810 3820 3830 3840 3850
PKAFDIGDYP IRLDDITNTL YHFELPTIII PEQKIDVPEI SLHLPAGVFI
3860 3870 3880 3890 3900
PKFGDLSATF KMASPIYNNT WTGNVENTEA GTVCTLKSTC TSTMVFLEYN
3910 3920 3930 3940 3950
LDAIATILLE NGALGLDAKS TFNHRDMNIN WKHDLRQNLR MKRDESSVSR
3960 3970 3980 3990 4000
PSRHTLGIDI ASQTFSDVSF RYASHNNGIT SSVSSPAAGF IGFQFTRRSP
4010 4020 4030 4040 4050
SQFYAKLFSR YLSTSDKDTD LLSLKMTLKN SEKLSVQVGY HFSGLSDMIN
4060 4070 4080 4090 4100
GLKDRLPSIL AALQKFINQY HIDHLGMDIN RAALKLKNAL SNGIDKAYLE
4110 4120 4130 4140 4150
IPRMFDATHT SFEQVKQHGN KMWRKMLESF PQDDLQEFSR RFFSSANEFI
4160 4170 4180 4190 4200
RTYESNMRAL LDAALKFLRN TKFHLPGLEE KLTGQELYNK FREYVSKAID
4210 4220 4230 4240 4250
RVTTRFYSLM EAIVDTISGH INKVEFTLPG TTEVISGKKI LKDLRSAMKS
4260 4270 4280 4290 4300
AKDTIMQAME EWEKLRSEEV FEDLMNYLKV YTQRAEDFLN SLKTEKLEEI
4310 4320 4330 4340 4350
SSRVSGIYKE AGNLEVMMKI REWMKEAKIG LTELKDFSKG VVQELYNQMS
4360 4370 4380 4390 4400
MEKLNSKLND LLMAVESYID SLFKSYLAFM KSLPSYTEPY VRVSNKKTDV
4410
DIPLPFYWKS FSEWPSMA
Length:4,418
Mass (Da):495,986
Last modified:March 8, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDB9B9375DEA205A6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX072551 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000062793; ENSDARP00000062792; ENSDARG00000042780

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX072551 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000062792

Proteomic databases

PaxDbiE7FBD3
PeptideAtlasiE7FBD3
PRIDEiE7FBD3

Genome annotation databases

EnsembliENSDART00000062793; ENSDARP00000062792; ENSDARG00000042780

Organism-specific databases

ZFINiZDB-GENE-070702-4, apoba

Phylogenomic databases

eggNOGiKOG4338, Eukaryota
GeneTreeiENSGT00590000083139
HOGENOMiCLU_000127_0_0_1
InParanoidiE7FBD3
OrthoDBi5350at2759
PhylomeDBiE7FBD3
TreeFamiTF331316

Enzyme and pathway databases

ReactomeiR-DRE-3000471, Scavenging by Class B Receptors
R-DRE-3000480, Scavenging by Class A Receptors
R-DRE-3000497, Scavenging by Class H Receptors
R-DRE-381426, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-DRE-432142, Platelet sensitization by LDL
R-DRE-5686938, Regulation of TLR by endogenous ligand
R-DRE-8856825, Cargo recognition for clathrin-mediated endocytosis
R-DRE-8856828, Clathrin-mediated endocytosis
R-DRE-8866423, VLDL assembly
R-DRE-8957275, Post-translational protein phosphorylation
R-DRE-8963888, Chylomicron assembly
R-DRE-8963901, Chylomicron remodeling
R-DRE-8964026, Chylomicron clearance
R-DRE-8964038, LDL clearance
R-DRE-8964041, LDL remodeling
R-DRE-975634, Retinoid metabolism and transport

Gene expression databases

BgeeiENSDARG00000042780, Expressed in multi-cellular organism and 20 other tissues

Family and domain databases

Gene3Di1.25.10.20, 1 hit
2.30.230.10, 1 hit
InterProiView protein in InterPro
IPR015819, Lipid_transp_b-sht_shell
IPR001747, Lipid_transpt_N
IPR009454, Lipid_transpt_open_b-sht
IPR011030, Lipovitellin_superhlx_dom
IPR015816, Vitellinogen_b-sht_N
IPR015255, Vitellinogen_open_b-sht
PfamiView protein in Pfam
PF06448, DUF1081, 1 hit
PF09172, DUF1943, 1 hit
PF01347, Vitellogenin_N, 1 hit
SMARTiView protein in SMART
SM01169, DUF1943, 1 hit
SM00638, LPD_N, 1 hit
SUPFAMiSSF48431, SSF48431, 1 hit
SSF56968, SSF56968, 2 hits
PROSITEiView protein in PROSITE
PS51211, VITELLOGENIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7FBD3_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7FBD3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: October 7, 2020
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again