UniProtKB - E7FB37 (E7FB37_DANRE)
Protein
Submitted name:
Polypyrimidine tract-binding protein 3
Gene
ptbp3
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- mRNA binding Source: GO_Central
GO - Biological processi
- mRNA processing Source: InterPro
- regulation of RNA splicing Source: GO_Central
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Polypyrimidine tract-binding protein 3Imported |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-091116-1, ptbp3 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000043757, Expressed in retina and 31 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 29 – 103 | RRMInterPro annotationAdd BLAST | 75 | |
Domaini | 153 – 229 | RRMInterPro annotationAdd BLAST | 77 | |
Domaini | 328 – 402 | RRMInterPro annotationAdd BLAST | 75 | |
Domaini | 445 – 520 | RRMInterPro annotationAdd BLAST | 76 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 26 | DisorderedSequence analysisAdd BLAST | 26 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 18 | PolarSequence analysisAdd BLAST | 18 |
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
eggNOGi | KOG1190, Eukaryota |
GeneTreei | ENSGT01010000222474 |
HOGENOMi | CLU_015171_7_1_1 |
OMAi | FHQHTGL |
OrthoDBi | 1545178at2759 |
TreeFami | TF319824 |
Family and domain databases
Gene3Di | 3.30.70.330, 4 hits |
InterProi | View protein in InterPro IPR006536, HnRNP-L/PTB IPR012677, Nucleotide-bd_a/b_plait_sf IPR021790, PTBP1_RRM IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF11835, RRM_8, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 4 hits |
SUPFAMi | SSF54928, SSF54928, 3 hits |
TIGRFAMsi | TIGR01649, hnRNP-L_PTB, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 4 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
E7FB37-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSSTPSTTA NGTDSKQYKG DRSPCAPSRV LHVRKVPIEV SEAEVVSLGV
60 70 80 90 100
PFGKVTNLLM LKGKNQAFIE MASEEAAMTM VNYYTTATPH VRNQPVYIQY
110 120 130 140 150
SNHRELKTDN LPNQGRAQAA LQAVNAVHTG NMSLSGTATA SDGGMMPGQS
160 170 180 190 200
PVLRIIVENL YYPVSLEVLH QIFSKFGTVL KIITFTKNNQ FQALLQYADP
210 220 230 240 250
MNAHHAKVAL DGQNIYNGCC TLRVEFSKLT SLNVKYNNDK SRDFTRLDLP
260 270 280 290 300
SGDGQPTLDP TMQTAFGAPG IISSPYPGAA GFAPAIGFPQ AGLSMQAMPG
310 320 330 340 350
ALGPLTIPSS AMTGRMAIHG MTPTAIHSVL LVSNLNPDSI SPHELFILFG
360 370 380 390 400
VYGDVHRVKI LFNKKENALI QMADATQAQL AMSHLNGQRL YGKVIRVTIS
410 420 430 440 450
KHQTVQLPRE GQEDQGLTKD FSGSPLHRFK KPGSKNFQNI FPPSATLHLS
460 470 480 490 500
NIPPSTTDDF LKDLFASSGY TVKAFKFFQK DRKMALIQLG SVEEAIQALI
510 520
HLHNHDLGEN HHLRVSFSKS TI
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8QRC0 | A0A2R8QRC0_DANRE | Polypyrimidine tract-binding protei... | ptbp3 | 514 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX510369 Genomic DNA No translation available. CR931761 Genomic DNA No translation available. |
RefSeqi | XP_009303446.1, XM_009305171.2 XP_009303447.1, XM_009305172.2 |
Genome annotation databases
Ensembli | ENSDART00000040308; ENSDARP00000040307; ENSDARG00000043757 ENSDART00000146727; ENSDARP00000118637; ENSDARG00000043757 |
GeneIDi | 798982 |
KEGGi | dre:798982 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX510369 Genomic DNA No translation available. CR931761 Genomic DNA No translation available. |
RefSeqi | XP_009303446.1, XM_009305171.2 XP_009303447.1, XM_009305172.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000040307 |
Genome annotation databases
Ensembli | ENSDART00000040308; ENSDARP00000040307; ENSDARG00000043757 ENSDART00000146727; ENSDARP00000118637; ENSDARG00000043757 |
GeneIDi | 798982 |
KEGGi | dre:798982 |
Organism-specific databases
CTDi | 9991 |
ZFINi | ZDB-GENE-091116-1, ptbp3 |
Phylogenomic databases
eggNOGi | KOG1190, Eukaryota |
GeneTreei | ENSGT01010000222474 |
HOGENOMi | CLU_015171_7_1_1 |
OMAi | FHQHTGL |
OrthoDBi | 1545178at2759 |
TreeFami | TF319824 |
Gene expression databases
Bgeei | ENSDARG00000043757, Expressed in retina and 31 other tissues |
Family and domain databases
Gene3Di | 3.30.70.330, 4 hits |
InterProi | View protein in InterPro IPR006536, HnRNP-L/PTB IPR012677, Nucleotide-bd_a/b_plait_sf IPR021790, PTBP1_RRM IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF11835, RRM_8, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 4 hits |
SUPFAMi | SSF54928, SSF54928, 3 hits |
TIGRFAMsi | TIGR01649, hnRNP-L_PTB, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E7FB37_DANRE | |
Accessioni | E7FB37Primary (citable) accession number: E7FB37 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 8, 2011 |
Last sequence update: | March 8, 2011 | |
Last modified: | April 7, 2021 | |
This is version 81 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |