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Entry version 67 (13 Feb 2019)
Sequence version 3 (20 Jun 2018)
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Protein
Submitted name:

Collagen, type VII, alpha 1

Gene

col7a1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • growth plate cartilage chondrocyte morphogenesis Source: GO_Central

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-1442490 Collagen degradation
R-DRE-1474244 Extracellular matrix organization
R-DRE-1650814 Collagen biosynthesis and modifying enzymes
R-DRE-2022090 Assembly of collagen fibrils and other multimeric structures
R-DRE-204005 COPII-mediated vesicle transport
R-DRE-216083 Integrin cell surface interactions
R-DRE-2214320 Anchoring fibril formation
R-DRE-5694530 Cargo concentration in the ER
R-DRE-8948216 Collagen chain trimerization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Collagen, type VII, alpha 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:col7a1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-030131-2427 col7a1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501717510224 – 3093Sequence analysisAdd BLAST3070

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
E7FA40

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000021720 Expressed in 12 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E7FA40 baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini34 – 206VWFAInterPro annotationAdd BLAST173
Domaini226 – 320Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini322 – 413Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini414 – 502Fibronectin type-IIIInterPro annotationAdd BLAST89
Domaini503 – 593Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini594 – 681Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini682 – 769Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini771 – 858Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini861 – 949Fibronectin type-IIIInterPro annotationAdd BLAST89
Domaini952 – 1040Fibronectin type-IIIInterPro annotationAdd BLAST89
Domaini1041 – 1130Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini1134 – 1311VWFAInterPro annotationAdd BLAST178
Domaini3040 – 3090BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3544 Eukaryota
ENOG410XNMM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154368

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E7FA40

Identification of Orthologs from Complete Genome Data

More...
OMAi
YRVSWHS

TreeFam database of animal gene trees

More...
TreeFami
TF351645

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 10 hits
cd00109 KU, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 10 hits
3.40.50.410, 2 hits
4.10.410.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01391 Collagen, 21 hits
PF00041 fn3, 8 hits
PF00014 Kunitz_BPTI, 1 hit
PF00092 VWA, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00759 BASICPTASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060 FN3, 10 hits
SM00327 VWA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 7 hits
SSF53300 SSF53300, 2 hits
SSF57362 SSF57362, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00280 BPTI_KUNITZ_1, 1 hit
PS50279 BPTI_KUNITZ_2, 1 hit
PS50853 FN3, 10 hits
PS50234 VWFA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E7FA40-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGCLLQWTLR LAVLLVLPSL SKAQGQCNDV VAADVVFLVD GSSSIGRANF
60 70 80 90 100
MLVKSFMAGI VKPFAKAVGP NGIRFGAVQY SDTARVEFTF TAYLNGTELI
110 120 130 140 150
TAVENINYKG GNTRTGAGLK YIADNFFSPA SIRDVPKISI LITDGKSQDN
160 170 180 190 200
VLEPSQKLRG LGVKIFAVGI KSADPAELKL IASPPQSEFT SQIGNFRALS
210 220 230 240 250
SLLPLVSRRV CTASGGSYSS DEAYSGPSDL QVLGETPDSL RFQWTSAGGP
260 270 280 290 300
VSGYVVQYRP LSAQGQPITA ELRQETIPNN QQSYNARELR SGTDYLITVI
310 320 330 340 350
AQYPNSLGES VSAKARTKPL LGVTTLRLVR AGFFSLALAW DAPAEQVQGY
360 370 380 390 400
RITYGPTGQP AARLEEQSVG AESTSLNLLG LKSNTEYAIN LLPLFPRNNG
410 420 430 440 450
SPASLTARTL PLEGVQQLSV ETISTSSVRV RWTGVTGARA YRVVWGPFTG
460 470 480 490 500
NDVETVELRG DSESHTLGNV RPDTEYIVTV IALYNGEAEG PAATTRFKIE
510 520 530 540 550
RSEQQVLRAT TTGPTSITLS WNLIQAARGY RLEWKVGERG RVLKQEFPQS
560 570 580 590 600
TTKYELRNLQ PNTEYIITLF TLYDGREEAT FFSTKSTEQS VGPVTNLRVV
610 620 630 640 650
DSLGNIIRIG WTGVTGATQY DIIILNTESN TEVNRRVPGN QTTFELRDLE
660 670 680 690 700
DDVRYAVSVT PLVGSKEGEQ ATVYIKTEAP LRVTNLRVVG SNSRRVRIAW
710 720 730 740 750
TGVSGATGYR ITWRQSNTAD QFRVVGADIT TYTIDGLQPD DTVAVGVAPV
760 770 780 790 800
VGGRTGEAVS VSARTTGTTG LVTGLRVAEV TSGRILIAWT PVNRATGYKI
810 820 830 840 850
IWRRSDGVED SENVSSDVAS YTIERLQEGA AYQVLVSALF NSREGPAATV
860 870 880 890 900
TARTDQATVG RVTNLQVLEA QGEVVQVSWV GVQNATSYRI FWRRTDGGEE
910 920 930 940 950
RNQLVGGNVT SVDLRQLDQG AQYEVKVLAL VQNREGPPVS VRVTTGGQRV
960 970 980 990 1000
TRVEDLRVLD SSPGRLRITW RAVSGASSYR VYWRSSQGEP ETSRLIGSDA
1010 1020 1030 1040 1050
TSYTLDGLRP GLSYTVRFSA LLNGVETEAT SIRVSTDALP PVTGLSVTDS
1060 1070 1080 1090 1100
TENSVLLGWS PVPGATGYIL RWTEVEDRGT TQSETLPSSA TSYRVMGLRL
1110 1120 1130 1140 1150
GRRYRFTVQS TFQNQVGPET SVEERTVCVG GRLDVVFLVP ASRDRSGLVG
1160 1170 1180 1190 1200
PVLSLLASSG GSFTSIGPRD SQMGVVMYSE DPKVRFLLNR HSNSETLLQD
1210 1220 1230 1240 1250
ILSTPFNNRP GNNIGQAMTY ARQFLLSAPA GRRSGVPGVV VIIADEKSTD
1260 1270 1280 1290 1300
NLSQPAAAVR ADGVTVLAVG VGRADPSELR LAVTDGSTQN LLYAQDANQL
1310 1320 1330 1340 1350
YGLHPDLADL LCGLARGTGV TGAKGERGEK GERGRDGVDG RKGEPGRDGL
1360 1370 1380 1390 1400
PGREGPRGPE GTPGQPGSSL GVKGEKGERG FPGLDGSSGI PGRSGAVGLP
1410 1420 1430 1440 1450
GSQGLPGIRG DPGEPGLIGP QGSKGEKGER GEAGSAIGGG LPGRKGEPGI
1460 1470 1480 1490 1500
PGIPGTPGRQ GVNGAKGEPG ARGLPGQDGR PGSQGTPGLS IKGLPGVGSG
1510 1520 1530 1540 1550
VAAKGDPGEP GSSGPQGPQG PRGVTGQKGA KGEPAESVEG QPGPKGNTGD
1560 1570 1580 1590 1600
PGDRGPRGPP GESGTKGDRG QAGAPGSDGA KGDRGPSGPA GDKGDKGSAG
1610 1620 1630 1640 1650
PSGPQGLRGL PGSNGLPGEK GAEGAKGEPG SSDPGSFGRK GERGERGFPG
1660 1670 1680 1690 1700
PAGAKGDKGD AAQKGERGAP GAGEPGQPGP KGDQGDRGPG GLSGKPGAKG
1710 1720 1730 1740 1750
SQGDAGERGE AGSPGSQGPM GPRGKDGLKG DKGEDGIAGE PGLPGKPGER
1760 1770 1780 1790 1800
GLRGLPGQSG QPGTKGDTGD PGEDGRNGTP GTMGPRGPKG DQGIQGPPGP
1810 1820 1830 1840 1850
PGDVTTGEKQ LRGEKGEKGE AGDPGEHGAK GLKGEAGAQG TAGSSGPEGQ
1860 1870 1880 1890 1900
RGLPGARGDP GDRGSPGEKG ERGAAGLDGR PGQDGKPGPP GPPGLRGDPG
1910 1920 1930 1940 1950
KQGDPGRDGL AGLRGPQGPP GPPGPPGADG TPGKAGEDGK SGLPGKTGED
1960 1970 1980 1990 2000
GVPGEDGRKG DKGEQGPAGR DGRDGIKGDR GIAGPSGPQG PVGPPGVPGN
2010 2020 2030 2040 2050
VGPPGSVVYV KGEPATPGPP GPQGPPGTPG IPGVPGAGGA RGERGLPGLK
2060 2070 2080 2090 2100
GDVGDPGEDG KPGTSADVKR ALSDFGIEVR ELKQLVDEKS VLMSRMSELS
2110 2120 2130 2140 2150
GKKGEKGEVG PRGPSGADGA RGLPGERGMK GEQGEKGPAG PQGPTGRAIG
2160 2170 2180 2190 2200
ERGPEGPPGQ AGEPGKPGIP GVPGRAGELG EAGRPGEKGD KGERGDKGPA
2210 2220 2230 2240 2250
GPAGLPGLGG PPGPKGDSAS VQSGLPGPRG LPGPAGVRGE PGAVGPQGSP
2260 2270 2280 2290 2300
GERGYTGARG EKGDKGASGE RGKDGSPGSQ GESGKPGQDG KPGLKGPAGP
2310 2320 2330 2340 2350
PGLSGNPGEP GIRGPTGPMG GNGPPGPPGV KGDHGEPGIG VQGPPGPQGN
2360 2370 2380 2390 2400
RGLPGPAGTP GAIGPQGPQG LPGQVGEGGK PGVPGRDGAP GKDGLPGLNG
2410 2420 2430 2440 2450
KQGIAGPVGP QGLKGEQGDS GPPGKSVTGP PGMKGEMGPP GQTLPGTPGE
2460 2470 2480 2490 2500
SGLPGLQGPK GDKGPAGIKG ERGAAGDPGD PGENGVRGPP GPKGVKGEAG
2510 2520 2530 2540 2550
VGMTGPPGQP GPIGLKGDPG LPGPPGPPGP RGLDGTPGLA GQRGEAGQPG
2560 2570 2580 2590 2600
PPGLPGERGL NGIIGKTGNP GTPGDAGPPG PTGAAGLPGL KGDKGEIGVG
2610 2620 2630 2640 2650
VPGQRGERGD PGPRGEEGRA GADGERGTTG PPGSKGNRGD KGEQGPSGIK
2660 2670 2680 2690 2700
GEKGETQLVG GPPGEKGVKG ETGERGPKGG QGEKGAKGQE GPPGEQGLRG
2710 2720 2730 2740 2750
EQGERGSTGF QGARGPGGQK GEAGQPGVPG EAGTPGKDGL PGMRGEKGEV
2760 2770 2780 2790 2800
GLIGLRGLKG ERGSKGVCGP SGQKGDKGDS GINGRPGLPG RKGEQGEVGL
2810 2820 2830 2840 2850
QGPIGSPGKE GLIGAKGDRG FDGVTGPKGA QGEKGERGPP GIPGSPGPRG
2860 2870 2880 2890 2900
VDGPPGLTGP QGPAGGKGPE GLQGQKGERG PPGPGMVGPR GTPGIPGERG
2910 2920 2930 2940 2950
EQGEIGPEGS KGDRGEAGMT EDEIRTYVRS EMNQHCACGG VQELQIPVPV
2960 2970 2980 2990 3000
QTYRSRSSTS PEHSLTRGDE EGQKLRVVMN TNDPDYEHIY SIETYDDDAP
3010 3020 3030 3040 3050
MVEIADYDST VNKSQAGRTN SVDSLKAERT KREVKVEDPC ILPMEEGDCS
3060 3070 3080 3090
RYTLRWYFNS QVDACRPFIY SGCGGNANRY LQKEECEKLC LQQ
Length:3,093
Mass (Da):313,133
Last modified:June 20, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8F71B18F2504171D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X1WHK5X1WHK5_DANRE
Collagen, type VII, alpha 1
col7a1
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX936393 Genomic DNA No translation available.
BX936415 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000033844; ENSDARP00000029446; ENSDARG00000021720
ENSDART00000154878; ENSDARP00000128470; ENSDARG00000021720

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX936393 Genomic DNA No translation available.
BX936415 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

PeptideAtlasiE7FA40

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000033844; ENSDARP00000029446; ENSDARG00000021720
ENSDART00000154878; ENSDARP00000128470; ENSDARG00000021720

Organism-specific databases

ZFINiZDB-GENE-030131-2427 col7a1

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410XNMM LUCA
GeneTreeiENSGT00940000154368
InParanoidiE7FA40
OMAiYRVSWHS
TreeFamiTF351645

Enzyme and pathway databases

ReactomeiR-DRE-1442490 Collagen degradation
R-DRE-1474244 Extracellular matrix organization
R-DRE-1650814 Collagen biosynthesis and modifying enzymes
R-DRE-2022090 Assembly of collagen fibrils and other multimeric structures
R-DRE-204005 COPII-mediated vesicle transport
R-DRE-216083 Integrin cell surface interactions
R-DRE-2214320 Anchoring fibril formation
R-DRE-5694530 Cargo concentration in the ER
R-DRE-8948216 Collagen chain trimerization

Gene expression databases

BgeeiENSDARG00000021720 Expressed in 12 organ(s), highest expression level in embryo
ExpressionAtlasiE7FA40 baseline

Family and domain databases

CDDicd00063 FN3, 10 hits
cd00109 KU, 1 hit
Gene3Di2.60.40.10, 10 hits
3.40.50.410, 2 hits
4.10.410.10, 1 hit
InterProiView protein in InterPro
IPR008160 Collagen
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF01391 Collagen, 21 hits
PF00041 fn3, 8 hits
PF00014 Kunitz_BPTI, 1 hit
PF00092 VWA, 2 hits
PRINTSiPR00759 BASICPTASE
SMARTiView protein in SMART
SM00060 FN3, 10 hits
SM00327 VWA, 1 hit
SUPFAMiSSF49265 SSF49265, 7 hits
SSF53300 SSF53300, 2 hits
SSF57362 SSF57362, 1 hit
PROSITEiView protein in PROSITE
PS00280 BPTI_KUNITZ_1, 1 hit
PS50279 BPTI_KUNITZ_2, 1 hit
PS50853 FN3, 10 hits
PS50234 VWFA, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7FA40_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7FA40
Secondary accession number(s): X1WE19
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: June 20, 2018
Last modified: February 13, 2019
This is version 67 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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