Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

MAP-kinase-activating death domain

Gene

madd

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-5357905 Regulation of TNFR1 signaling
R-DRE-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Submitted name:
MAP-kinase-activating death domainImported
Gene namesi
Name:maddImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-030131-8076 madd

PTM / Processingi

Proteomic databases

PaxDbiE7F6X3
PeptideAtlasiE7F6X3
PRIDEiE7F6X3

Expressioni

Gene expression databases

BgeeiENSDARG00000003495
ExpressionAtlasiE7F6X3 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000047207

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 485UDENNInterPro annotationAdd BLAST482

Phylogenomic databases

eggNOGiKOG3570 Eukaryota
ENOG410XP23 LUCA
GeneTreeiENSGT00760000118819
InParanoidiE7F6X3
OrthoDBiEOG091G00AV
TreeFamiTF318583

Family and domain databases

InterProiView protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR037516 Tripartite_DENN
PfamiView protein in Pfam
PF02141 DENN, 1 hit
SMARTiView protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
PROSITEiView protein in PROSITE
PS50211 DENN, 1 hit

Sequencei

Sequence statusi: Complete.

E7F6X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLSTIVLSP LLNTTNEYIT STLYFLHTGE KPAHTDTAVE ATEKSDPSTL
60 70 80 90 100
TLSGEHSAPP AGDGTLLPGE PGSSGKSPRS KRSGRIAPQN RNSMLTSLCI
110 120 130 140 150
LSHYPFFSTF RECLYILKRM VDCCSQRLNQ RPGAPKSTQR DTMWRVFTGA
160 170 180 190 200
LSVEEKEKGS QVLQDLREIE SWVYRLLRSP VPVAGQRRVD VEVLPHELQP
210 220 230 240 250
ALTFALPDPS RFSIVDFPLH LPLELLGVDA CLQVLACILL EHKVVLQSRD
260 270 280 290 300
YNALSMSVMA FVSMIYPLEY MFPVIPLLPT CMASAEQLLL APTPYVIGVP
310 320 330 340 350
ASFFLYKCDF KMPDDVWLVD LDCNKVIVPS NAELLPPLPE PEASELKKHL
360 370 380 390 400
KQALASMSLN TQPILNLEKF QDGQELSLLP PGRDKASPSS TEFNPLIYGN
410 420 430 440 450
DVDSVDVATR VAMVRFFNSP NVLQGFQMHT RTLRLFPRPV VAFQSTSFLA
460 470 480 490 500
SRPRRNGFTE KLSHTQAVEY YGEWALNPTN LAFQRIHNNV YDPSLIGDKP
510 520 530 540 550
KWYAHQLQPV FYRVYDGNSH LAEALSGPLQ DETNDSDPTD DSGSDSEAYD
560 570 580 590 600
DSSSSYSSLG DFVNEMIKGD IQGDTPNVDP LTHAALGDAD EVEIHDFHEY
610 620 630 640 650
KGNSGEPEPE GPTEAADSQP LRSSSSTTAS SSPSTVIQGV NHEQKEPVEV
660 670 680 690 700
EPIANVTYPS SAPVLGPPPF TRPTPDPTLV DPANKKREYD NPYFEPQYGF
710 720 730 740 750
PTEEDAETDE QEESYTPRFN QNLNGNKPSR PLRPSSLKLP GESDGEGDSR
760 770 780 790 800
NSSPNSTISN NSSDGFGGLM SFASNLYKNH GTSFSLSSLA LPNKAREKNT
810 820 830 840 850
PFPSLKGARA PRALVDQKSS VIKHSPTVKR ESPSPQGRAN NTSENQQFLK
860 870 880 890 900
EVVQSVLEGQ GVGWLNMKKV RRLLENEQLR VFVLSKLNRA VQSEEDAQQE
910 920 930 940 950
VIRDVEINRK VYKGMLDILK CTVSSLEHSY TNAGLGGMAS VFSLLEIART
960 970 980 990 1000
HYQTKGADGV KQRVEGGDTE EKKSQISADS GLSVTSGSQK SDTDSLASSE
1010 1020 1030 1040 1050
PPALTRSTSQ DSEASTVVSN SSGETLGADS DLSSTAGDGL TGRHGQHLNL
1060 1070 1080 1090 1100
SRGTLSDSEI ETNPATSSVF GKTHKLKPGV KEPVGVNKAA PAPPVEDVSM
1110 1120 1130 1140 1150
RIYLCEGLLG KERSTLWDQM QFWEDAFLDA VMLEREGMGM DQGPQEMIDR
1160 1170 1180 1190 1200
YLSLGDHDRK RLEDDEDRLL ATLLHNMIAY MLMMKVGKND IRKKVRRLMG
1210 1220 1230 1240 1250
KSHIGLTHSQ EINEVLDRLA HLSGRELSIR PSGSRHIKKQ TFVVHAGTDT
1260 1270 1280 1290 1300
TGDIFFMEVC DDCIVLRSNI GTVYERWWYE KLINMTYCPK TKVLCLWRRN
1310 1320 1330 1340 1350
GQETQLNKFY TKKCRELYYC VKDSMERAAA RQQSIKPGPE LGGEFPVQDM
1360 1370 1380 1390 1400
KTGEGGLLQV TLEGINLKFM HSQVFIELNH IKKCNTVKGV FVLEEFVPET
1410 1420 1430 1440
KEVVIHKYKT PMAHQICYSV LCLFSYMAAV KGKESEGKPK MLSPRPLAS
Length:1,449
Mass (Da):160,614
Last modified:June 20, 2018 - v3
Checksum:i596215B9861EC18C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR388195 Genomic DNA No translation available.
CU075709 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000047208; ENSDARP00000047207; ENSDARG00000003495

Similar proteinsi

Entry informationi

Entry nameiE7F6X3_DANRE
AccessioniPrimary (citable) accession number: E7F6X3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: June 20, 2018
Last modified: July 18, 2018
This is version 52 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health