UniProtKB - E7F500 (E7F500_DANRE)
Protein
Submitted name:
Zinc finger and BTB domain-containing 17
Gene
zbtb17
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of T cell migration Source: ZFIN
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
Reactomei | R-DRE-212436, Generic Transcription Pathway |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger and BTB domain-containing 17Imported |
Gene namesi | Name:zbtb17Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-090313-240, zbtb17 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000074548, Expressed in blastula and 25 other tissues |
ExpressionAtlasi | E7F500, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 24 – 86 | BTBInterPro annotationAdd BLAST | 63 | |
Domaini | 326 – 353 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 354 – 381 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 382 – 409 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 410 – 437 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 438 – 465 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 466 – 493 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 494 – 521 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 522 – 545 | C2H2-typeInterPro annotationAdd BLAST | 24 | |
Domaini | 570 – 598 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 697 – 724 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 130 – 306 | DisorderedSequence analysisAdd BLAST | 177 | |
Regioni | 756 – 794 | DisorderedSequence analysisAdd BLAST | 39 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 669 – 689 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 130 – 170 | PolyampholyteSequence analysisAdd BLAST | 41 | |
Compositional biasi | 192 – 216 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 233 – 247 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 270 – 300 | AcidicSequence analysisAdd BLAST | 31 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159957 |
HOGENOMi | CLU_002678_30_0_1 |
InParanoidi | E7F500 |
OrthoDBi | 1318335at2759 |
PhylomeDBi | E7F500 |
TreeFami | TF332047 |
Family and domain databases
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 8 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 10 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 10 hits PS50157, ZINC_FINGER_C2H2_2, 10 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
E7F500-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDFPWHSGKV LGQLNEQRQL GLLCDCTFVV DGVDFKAHKA VLAACSSYFR
60 70 80 90 100
TLFLDQKDVV HLDISNAAGL EQVLEFMYTA KLTLNAQNIE DVLAVATFLQ
110 120 130 140 150
MQEIVNACSA FQSLTPGKSG LSKAIPLEEQ TKSVKKPEEP DSHSVTQKAG
160 170 180 190 200
PEEKEAQSQS KTEETHEAVS NVAEKQSTKT LRAVSKISGP LKTRQKDSKS
210 220 230 240 250
ESEAERATKE LPQFQDDPND ADYTPKLSQR MVAKRSVVST RRSKSKYATV
260 270 280 290 300
HTAAEVNDGE ESVSKVESMV EEENEDDGGE EDLEDDQTDG EEEMETEDGE
310 320 330 340 350
MMDSEDRKFA IGAERTESRS YGSITHKCED CGKKFTHTGN FKRHMRIHTG
360 370 380 390 400
EKPFTCRDCN KAFSDPAACK AHEKTHSPVK PYCCSTCGKS YRQISLLNLH
410 420 430 440 450
RKRHTDEARY SCEDCGKLFT TSGNLKRHQL VHSGEKPYQC DHCDRAFSDP
460 470 480 490 500
TAKMRHLETH DTDKGHKCQH CDKKFNQVGN LKAHLKIHIA DGPLKCKECG
510 520 530 540 550
KQFTTSGNLK RHLRVHSGEK PFICMHCQRA FADPGALQRH VRIHTVSLLH
560 570 580 590 600
CFSSLIAHVR QHTGEKPYPF LCDKCGRGFN RVDNLRSHVK TVHQGKAGMK
610 620 630 640 650
RLVVAEDDDG EDKLLADSNP DSELDSNEVN IVTVTTDDIV TLATEALAAT
660 670 680 690 700
TVAQLTVAPK GIYYASVSAD ETEALKAEIT KAVEKVQEAD PNTQILYACD
710 720 730 740 750
SCGEKFLDAS SLAQHVRIHT AQALVMFQAD SDFYQQYTGD ATWQTTEQVI
760 770 780 790
QGGELLFRTR DEESEEAQPE SQMDGAEVES EDGAEKVHSE SQQQ
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF1QL56 | F1QL56_DANRE | Zinc finger and BTB domain-containi... | zbtb17 | 491 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR925709 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000114840; ENSDARP00000102422; ENSDARG00000074548 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR925709 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000102422 |
Proteomic databases
PaxDbi | E7F500 |
Genome annotation databases
Ensembli | ENSDART00000114840; ENSDARP00000102422; ENSDARG00000074548 |
Organism-specific databases
ZFINi | ZDB-GENE-090313-240, zbtb17 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159957 |
HOGENOMi | CLU_002678_30_0_1 |
InParanoidi | E7F500 |
OrthoDBi | 1318335at2759 |
PhylomeDBi | E7F500 |
TreeFami | TF332047 |
Enzyme and pathway databases
Reactomei | R-DRE-212436, Generic Transcription Pathway |
Gene expression databases
Bgeei | ENSDARG00000074548, Expressed in blastula and 25 other tissues |
ExpressionAtlasi | E7F500, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 8 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 10 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 6 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 10 hits PS50157, ZINC_FINGER_C2H2_2, 10 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E7F500_DANRE | |
Accessioni | E7F500Primary (citable) accession number: E7F500 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 8, 2011 |
Last sequence update: | June 20, 2018 | |
Last modified: | December 2, 2020 | |
This is version 81 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |