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Protein

Oxysterol-binding protein

Gene

osbpl6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Biological processi

Keywordsi

Biological processLipid transportUniRule annotation, Transport

Enzyme and pathway databases

ReactomeiR-DRE-192105 Synthesis of bile acids and bile salts

Names & Taxonomyi

Protein namesi
Recommended name:
Oxysterol-binding proteinUniRule annotation
Gene namesi
Name:osbpl6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-070912-206 osbpl6

PTM / Processingi

Proteomic databases

PaxDbiE7F2M8

Expressioni

Gene expression databases

BgeeiENSDARG00000063730 Expressed in 8 organ(s), highest expression level in brain
ExpressionAtlasiE7F2M8 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000107551

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 165PHInterPro annotationAdd BLAST96

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili396 – 423Sequence analysisAdd BLAST28
Coiled coili836 – 864Sequence analysisAdd BLAST29

Sequence similaritiesi

Belongs to the OSBP family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1737 Eukaryota
ENOG410XP9E LUCA
GeneTreeiENSGT00760000119155
InParanoidiE7F2M8
OMAiFVKGNYW
TreeFamiTF320922

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR037239 OSBP_sf
IPR000648 Oxysterol-bd
IPR018494 Oxysterol-bd_CS
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR10972 PTHR10972, 1 hit
PfamiView protein in Pfam
PF01237 Oxysterol_BP, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF144000 SSF144000, 1 hit
PROSITEiView protein in PROSITE
PS01013 OSBP, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

E7F2M8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRHQSRTTS LEEKVATPIH RSTAPLQKSS TPTHKSASSS SSSQRDSRQE
60 70 80 90 100
PDSWEIIEGL RIGQTHVQRP EKHEGFMLKK RKWPLKGWHK RFFVLDNGIL
110 120 130 140 150
KYSKSPVDIQ KGKLHGSIDV GLSVMSIKKR ARRIDLDTEE HIYHLKVKSP
160 170 180 190 200
DVFDLWVCKL RHHRLFRQNE IVRSPRDATL RTFPPSAGAE SPQNTPSSTH
210 220 230 240 250
PKKGKPSSFP WQLPPSCSNG QSKVAAWLQE SEEMDKCAEE LAYCQSSLLE
260 270 280 290 300
LNQLLQSLEI LQRTQSAPNF TDMQSNCVDL SKKEKRVSRR WRTKSVSKDA
310 320 330 340 350
KLQQQVPLSA SMSQVRLHSS NPNLCAELAD FQAPVTRLTD GIDSAGDYIK
360 370 380 390 400
LQEDFCIIAQ KVHSLLKSAF NTVAIEKEKI KQVLLDHEQT GQSNQIVTLR
410 420 430 440 450
RSLSQALSQN AELKTRLNRI HSESVLSEQV VSVNIISSPD EACEPLHVGL
460 470 480 490 500
PLSQQVSNES RLSMSESVSE FFDAQEVLLS ASSSENEASD DESYVSDVSD
510 520 530 540 550
NISEDNASVT DNVSRQMPNG ELASSMFRNG RRPCLPAPAP DTSNINLWNI
560 570 580 590 600
LKNNIGKDLS KVSMPVELNE PLNTLQHMCE ELEYTELLDK AAQTDDPYER
610 620 630 640 650
MAIVAAFAVS GYSSTYYRAG SKPFNPLLGE TYECIREDKG FCFFSEQVSH
660 670 680 690 700
HPPISACHCD SQNFTFWQDV RWKNKFWGKS MEILPIGTVN VMLPSYGDHY
710 720 730 740 750
EWNKVTTCVH NILSGRRWIE HYGEVTIRNT RSTTCICKLS FIKGNYWSSN
760 770 780 790 800
VNEVQGSVMD QEGRVIHRLF GKWHEGLYCG VPPSAKCIWR PGSMPTDYEL
810 820 830 840 850
YYGFTRFAVE LNELFPEMKE LLPPTDARFR PDQRFLEEGN VQMATAEKQR
860 870 880 890 900
IEEQQRNRRK WMEENNIKHQ PRFFKKVMDS NQRERWVSNS MYWELRKDPG
910
FLKLENPELW
Length:910
Mass (Da):104,084
Last modified:April 5, 2011 - v2
Checksum:i786A2823CC710FF9
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B0S523B0S523_DANRE
Oxysterol-binding protein-like 6
osbpl6
903Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX004991 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000124777; ENSDARP00000107551; ENSDARG00000063730

Similar proteinsi

Entry informationi

Entry nameiE7F2M8_DANRE
AccessioniPrimary (citable) accession number: E7F2M8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 50 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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