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Entry version 49 (31 Jul 2019)
Sequence version 1 (08 Mar 2011)
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Protein
Submitted name:

Mucin-4

Gene

MUC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Mucin-4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MUC4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7514 MUC4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000145113

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500321736029 – 4400Sequence analysisAdd BLAST4372

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E7EW47

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E7EW47

PeptideAtlas

More...
PeptideAtlasi
E7EW47

PRoteomics IDEntifications database

More...
PRIDEi
E7EW47

ProteomicsDB human proteome resource

More...
ProteomicsDBi
18771

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000145113 Expressed in 134 organ(s), highest expression level in nasal cavity epithelium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E7EW47 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni40 – 87DisorderedSequence analysisAdd BLAST48
Regioni142 – 249DisorderedSequence analysisAdd BLAST108
Regioni267 – 286DisorderedSequence analysisAdd BLAST20
Regioni303 – 328DisorderedSequence analysisAdd BLAST26
Regioni353 – 383DisorderedSequence analysisAdd BLAST31
Regioni438 – 473DisorderedSequence analysisAdd BLAST36
Regioni488 – 580DisorderedSequence analysisAdd BLAST93
Regioni592 – 853DisorderedSequence analysisAdd BLAST262
Regioni868 – 963DisorderedSequence analysisAdd BLAST96
Regioni983 – 1864DisorderedSequence analysisAdd BLAST882
Regioni1878 – 2078DisorderedSequence analysisAdd BLAST201
Regioni2111 – 2220DisorderedSequence analysisAdd BLAST110
Regioni2232 – 2814DisorderedSequence analysisAdd BLAST583
Regioni2837 – 3306DisorderedSequence analysisAdd BLAST470
Regioni3320 – 3580DisorderedSequence analysisAdd BLAST261
Regioni3592 – 3644DisorderedSequence analysisAdd BLAST53
Regioni3656 – 3756DisorderedSequence analysisAdd BLAST101
Regioni3769 – 4223DisorderedSequence analysisAdd BLAST455
Regioni4242 – 4288DisorderedSequence analysisAdd BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi304 – 328PolarSequence analysisAdd BLAST25
Compositional biasi488 – 530PolarSequence analysisAdd BLAST43
Compositional biasi543 – 580PolarSequence analysisAdd BLAST38

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHUZ Eukaryota
ENOG4111F6U LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000110943

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039898 Mucin_4

The PANTHER Classification System

More...
PANTHERi
PTHR13802:SF53 PTHR13802:SF53, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 55 potential isoforms that are computationally mapped.Show allAlign All

E7EW47-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKGARWRRVP WVSLSCLCLC LLPHVVPGTT EDTLITGSKT AAPVTSTGST
60 70 80 90 100
TATLEGQSTA ASSRTSNQDI SASSQNHQTK STETTSKAQT DTLTQMMTST
110 120 130 140 150
LFSSPSVHNV METAPPDEMT TSFPSSVTNT LMMTSKTITM TTSTDSTLGN
160 170 180 190 200
TEETSTAGTE SSTPVTSAVS ITAGQEGQSR TTSWRTSIQD TSASSQNHWT
210 220 230 240 250
RSTQTTRESQ TSTLTHRTTS TPSFSPSVHN VTGTVSQKTS PSGETATSSL
260 270 280 290 300
CSVTNTSMMT SEKITVTTST GSTLGNPGET SSVPVTGSLM PVTSAALVTF
310 320 330 340 350
DPEGQSPATF SRTSTQDTTA FSKNHQTQSV ETTRVSQINT LNTLTPVTTS
360 370 380 390 400
TVLSSPSGFN PSGTVSQETF PSGETTTSSP SSVSNTFLVT SKVFRMPTSR
410 420 430 440 450
DSTLGNTEET SLSVSGTISA ITSKVSTIWW SDTLSTALSP SSLPPKISTA
460 470 480 490 500
FHTQQSEGAE TTGRPHERSS FSPGVSQEIF TLHETTTWPS SFSSKGHTTW
510 520 530 540 550
SQTELPSTST GAATRLVTGN PSTGTAGTIP RVPSKVSAIG EPGEPTTYSS
560 570 580 590 600
HSTTLPKTTG AGAQTQWTQE TGTTGEALLS SPSYSVTQMI KTATSPSSSP
610 620 630 640 650
MLDRHTSQQI TTAPSTNHST IHSTSTSPQE SPAVSQRGHT QAPQTTQESQ
660 670 680 690 700
TTRSVSPMTD TKTVTTPGSS FTASGHSPSE IVPQDAPTIS AATTFAPAPT
710 720 730 740 750
GDGHTTQAPT TALQAAPSSH DATLGPSGGT SLSKTGALTL ANSVVSTPGG
760 770 780 790 800
PEGQWTSASA STSPDTAAAM THTHQAESTE ASGQTQTSEP ASSGSRTTSA
810 820 830 840 850
GTATPSSSGA SGTTPSGSEG ISTSGETTRF SSNPSRDSHT TQSTTELLSA
860 870 880 890 900
SASHGAIPVS TGMASSIVPG TFHPTLSEAS TAGRPTGQSS PTSPSASPQE
910 920 930 940 950
TAAISRMAQT QRTRTSRGSD TISLASQATD TFSTVPPTPP SITSTGLTSP
960 970 980 990 1000
QTETHTLSPS GSGKTFTTAL ISNATPLPVT YASSASTGHT TPLHVTDASS
1010 1020 1030 1040 1050
VSTGHATPLP VTSPSSVSTG HTTPLPVTDT SSESTGHVTP LPVTSFSSAS
1060 1070 1080 1090 1100
TGDSTPLPVT DTSSASTGHV TPLPVTSLSS ASTGDTTPLP VTDTSSASTG
1110 1120 1130 1140 1150
HATSLPVTDT SSVSTGHTTP LPVTDTSSAS TGHATSLPVT DTSSVSTGHT
1160 1170 1180 1190 1200
TPLHVTDASS ASTGQATPLP VTSLSSVSTG DTTPLPVTSP SSASTGHATP
1210 1220 1230 1240 1250
LLVTDTSSAS TGHATPLPVT DASSVSTDHA TSLPVTIPSA ASTGHTTPLP
1260 1270 1280 1290 1300
VTDTSSASTG QATSLLVTDT SSVSTGDTTP LPVTSTSSAS TGHVTPLHVT
1310 1320 1330 1340 1350
SPSSASTGHA TPLPVTSLSS ASTGDTMPLP VTSPSSASTG DTTPLPVTDA
1360 1370 1380 1390 1400
SSVSTGHTTP LHVTDASSAS TGQATPLPVT SLSSVSTGDT TPLPVTSPSS
1410 1420 1430 1440 1450
ASTGHATPLL VTDTSSASTG HATPLPVTDA SSVSTDHATS LPVTIPSAAS
1460 1470 1480 1490 1500
TGHTTPLPVT DTSSASTGQA TSLLVTDTSS VSTGDTTPLP VTSTSSASTG
1510 1520 1530 1540 1550
HVTPLHVTSP SSASTGHATP LPVTSLSSAS TGDTMPLPVT SPSSASTGDT
1560 1570 1580 1590 1600
TPLPVTDASS VSTGHTTPLP VTSPSSASTG HTTPLPVTDT SSASKGDTTP
1610 1620 1630 1640 1650
LPVTSPSSAS TGHTTPLPVT DTSSASTGDT TPLPVTNASS LSTGHATPLH
1660 1670 1680 1690 1700
VTSPSSASTG HATPLPVTST SSASTGHATP LPVTGLSSAT TDDTTRLPVT
1710 1720 1730 1740 1750
DVSSASTGQA TPLPVTSLSS VSTGDTTPLP VTSPSSASTG HASPLLVTDA
1760 1770 1780 1790 1800
SSASTGQATP LPVTDTSSVS TAHATPLPVT GLSSASTDDT TRLPVTDVSS
1810 1820 1830 1840 1850
ASTGQAIPLP VTSPSSASTG DTTPLPVTDA SSASTGDTTS LPVTIPSSAS
1860 1870 1880 1890 1900
SGHTTSLPVT DASSVSTGHA TSLLVTDASS VSTGDTTPLP VTDTNSASTG
1910 1920 1930 1940 1950
DTTPLHVTDA SSVSTGHATS LPVTSLSSAS TGDTTPLPVT SPSSASSGHT
1960 1970 1980 1990 2000
TPLPVTDASS VPTGHATSLP VTDASSVSTG HATPLPVTDA SSVSTGHATP
2010 2020 2030 2040 2050
LPVTDTSSVS TGQATPLPVT SLSSASTGDT TPLPVTDTSS ASTGQDTPLP
2060 2070 2080 2090 2100
VTSLSSVSTG DTTPLPVTNP SSASTGHATP LLVTDASSIS TGHATSLLVT
2110 2120 2130 2140 2150
DASSVSTGHA TALHDTDASS LSTGDTTPLP VTSPSSTSTG DTTPLPVTET
2160 2170 2180 2190 2200
SSVSTGHATS LPVTDTSSAS TGHATSLPVT DTSSASTGHA TPLPVTDTSS
2210 2220 2230 2240 2250
ASTGQATPLP VTSPSSASTG HAIPLLVTDT SSASTGQATP LPVTSLSSAS
2260 2270 2280 2290 2300
TGDTTPLPVT DASSVSTGHA TSLPVTSLSS VSTGDTTPLP VTSPSSASTG
2310 2320 2330 2340 2350
HATPLHVTDA SSASTGHATP LPVTSLSSAS TGDTTPLPVT SPSSASTGHA
2360 2370 2380 2390 2400
TPLHVTDASS VSTGDTTPLP VTSSSSASSG HTTPLPVTDA SSASTGDTTP
2410 2420 2430 2440 2450
LPVTDTSSAS TGHATHLPVT GLSSASTGDT TRLPVTNVSS ASTGHATPLP
2460 2470 2480 2490 2500
VTSTSSASTG DTTPLPGTDT SSVSTGHTTP LLVTDASSVS TGDTTRLPVT
2510 2520 2530 2540 2550
SPSSASTGHT TPLPVTDTPS ASTGDTTPLP VTNASSLSTR HATSLHVTSP
2560 2570 2580 2590 2600
SSASTGHATS LPVTDTSAAS TGHATPLPVT STSSASTGDT TPLPVTDTYS
2610 2620 2630 2640 2650
ASTGQATPLP VTSLSSVSTG DTTPLPVTSP SSASTGHATP LLVTDASSAS
2660 2670 2680 2690 2700
TGQATPLPVT SLSSVSTGDT TPLPVTSPSS ASTGHATSLP VTDTSSASTG
2710 2720 2730 2740 2750
DTTSLPVTDT SSAYTGDTTS LPVTDTSSSS TGDTTPLLVT ETSSVSTGDT
2760 2770 2780 2790 2800
TPLPVTDTSS ASTGHATPLP VTNTSSVSTG HATPLHVTSP SSASTGHTTP
2810 2820 2830 2840 2850
LPVTDASSVS TGHATSLPVT DASSVFTGHA TSLPVTIPSS ASSGHTTPLP
2860 2870 2880 2890 2900
VTDASSVSTG HATSLPVTDA SSVSTGHATP LPVTDASSVS TGHATPLPLT
2910 2920 2930 2940 2950
SLSSVSTGDT TPLPVTDTSS ASTGQATPLP VTSLSSVSTG DTTPLPVTDT
2960 2970 2980 2990 3000
SSASTGHATS LPVTDTSSAS TGHATPLPDT DTSSASTGHA TLLPVTDTSS
3010 3020 3030 3040 3050
ASIGHATSLP VTDTSSISTG HATPLHVTSP SSASTGHATP LPVTDTSSAS
3060 3070 3080 3090 3100
TGHANPLHVT SPSSASTGHA TPLPVTDTSS ASTGHATPLP VTSLSSVSTG
3110 3120 3130 3140 3150
DTTPLPVTSP SSASTGHTTP LPVTDTSSAS TGQATALPVT STSSASTGDT
3160 3170 3180 3190 3200
TPLPVTDTSS ASTGQATPLP VTSLSSVSTG DTTPLPVTSP SSASTGHATP
3210 3220 3230 3240 3250
LLVTDASSAS TGQATPLPVT SLSSVSTGDT TPLPVTSPSS ASTGHATSLP
3260 3270 3280 3290 3300
VTDTSSASTG DTTSLPVTDT SSAYTGDTTS LPVTDTSSSS TGDTTPLLVT
3310 3320 3330 3340 3350
ETSSVSTGHA TPLLVTDASS ASTGHATPLH VTSPSSASTG DTTPVPVTDT
3360 3370 3380 3390 3400
SSVSTGHATP LPVTGLSSAS TGDTTRLPVT DISSASTGQA TPLPVTNTSS
3410 3420 3430 3440 3450
VSTGDTMPLP VTSPSSASTG HATPLPVTST SSASTGHATP VPVTSTSSAS
3460 3470 3480 3490 3500
TGHTTPLPVT DTSSASTGDT TPLPVTSPSS ASTGHTTPLH VTIPSSASTG
3510 3520 3530 3540 3550
DTSTLPVTGA SSASTGHATP LPVTDTSSVS TGHATPLPVT SLSSVSTGDT
3560 3570 3580 3590 3600
TPLPVTDASS ASTGQATPLP VTSLSSVSTG DTTPLLVTDA SSVSTGHATP
3610 3620 3630 3640 3650
LPVTDTSSAS TGDTTRLPVT DTSSASTGQA TPLPVTSLSS VSTGDTTPLL
3660 3670 3680 3690 3700
VTDASSVSTG HATPLPVTDT SSASTGDTTR LPVTDTSSAS TGQATPLPVT
3710 3720 3730 3740 3750
IPSSSSSGHT TPLPVTSTSS VSTGHVTPLH VTSPSSASTG HVTPLPVTST
3760 3770 3780 3790 3800
SSASTGHATP LLVTDASSVS TGHATPLPVT DASSASTGDT TPLPVTDTSS
3810 3820 3830 3840 3850
ASTGQATPLP VTSLSSVSTG DTTPLPVTDA SSASTGHATP LPVTIPSSVS
3860 3870 3880 3890 3900
TGDTMPLPVT SPSSASTGHA TPLPVTGLSS ASTGDTTPLP VTDTSSASTR
3910 3920 3930 3940 3950
HATPLPVTDT SSASTDDTTR LPVTDVSSAS TGHATPLPVT STSSASTGDT
3960 3970 3980 3990 4000
TPLPVTDTSS VSTGHATSLP VTSRSSASTG HATPLPVTDT SSVSTGHATP
4010 4020 4030 4040 4050
LPVTSTSSVS TGHATPLPVT SPSSASTGHA TPVPVTSTSS ASTGDTTPLP
4060 4070 4080 4090 4100
VTNASSLSTG HATPLHVTSP SSASRGDTST LPVTDASSAS TGHATPLPLT
4110 4120 4130 4140 4150
SLSSVSTGDT TPLPVTDTSS ASTGQATPLP VTSLSSVSTG DTTPLPVTIP
4160 4170 4180 4190 4200
SSASSGHTTS LPVTDASSVS TGHGTPLPVT STSSASTGDT TPLPVTDTSS
4210 4220 4230 4240 4250
ASTGHATPLP VTDTSSASTG HATPLPVTSL SSVSTGHATP LAVSSATSAS
4260 4270 4280 4290 4300
TVSSDSPLKM ETPGMTTPSL KTDGGRRTAT SPPPTTSQTI ISTIPSTAMH
4310 4320 4330 4340 4350
TRSTAAPIPI LPERGVSLFP YGAGAGDLEF VRRTVDFTSP LFKPATGFPL
4360 4370 4380 4390 4400
GSSLRDSLYA SQAGTLWPWW LRSGTMLTSP LVGGPHFIRN TRRSMVNTAC
Length:4,400
Mass (Da):429,631
Last modified:March 8, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC098A5EF9FE1DD53
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 55 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99102MUC4_HUMAN
Mucin-4
MUC4
2,169Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PDY6E9PDY6_HUMAN
Mucin-4
MUC4
5,412Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7ENC5E7ENC5_HUMAN
Mucin-4
MUC4
5,360Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JS65A0A0G2JS65_HUMAN
Mucin-4
MUC4
7,418Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JSC3A0A0G2JSC3_HUMAN
Mucin-4
MUC4
1,176Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JR97A0A0G2JR97_HUMAN
Mucin-4
MUC4
7,366Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JRA1A0A0G2JRA1_HUMAN
Mucin-4
MUC4
5,386Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JNL3A0A0G2JNL3_HUMAN
Mucin-4
MUC4
2,138Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JM16A0A0G2JM16_HUMAN
Mucin-4
MUC4
5,314Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JQT8A0A0G2JQT8_HUMAN
Mucin-4
MUC4
5,334Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC069513 Genomic DNA No translation available.
AC233280 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENST00000477086; ENSP00000419989; ENSG00000145113

UCSC genome browser

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UCSCi
uc062rxw.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069513 Genomic DNA No translation available.
AC233280 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

jPOSTiE7EW47
MaxQBiE7EW47
PeptideAtlasiE7EW47
PRIDEiE7EW47
ProteomicsDBi18771

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000477086; ENSP00000419989; ENSG00000145113
UCSCiuc062rxw.1 human

Organism-specific databases

HGNCiHGNC:7514 MUC4
OpenTargetsiENSG00000145113

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IHUZ Eukaryota
ENOG4111F6U LUCA
GeneTreeiENSGT00730000110943

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
MUC4 human

Gene expression databases

BgeeiENSG00000145113 Expressed in 134 organ(s), highest expression level in nasal cavity epithelium
ExpressionAtlasiE7EW47 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR039898 Mucin_4
PANTHERiPTHR13802:SF53 PTHR13802:SF53, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7EW47_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7EW47
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 31, 2019
This is version 49 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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