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Protein

Cytoplasmic FMR1-interacting protein

Gene

CYFIP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cytoplasmic FMR1-interacting proteinUniRule annotation
Gene namesi
Name:CYFIP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000055163.18
HGNCiHGNC:13760 CYFIP2

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000055163

PTM / Processingi

Proteomic databases

EPDiE7EVJ5
MaxQBiE7EVJ5
PeptideAtlasiE7EVJ5
PRIDEiE7EVJ5

Expressioni

Gene expression databases

BgeeiENSG00000055163
ExpressionAtlasiE7EVJ5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7EVJ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CYFIP family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3534 Eukaryota
ENOG410XPKW LUCA
GeneTreeiENSGT00500000044831
TreeFamiTF312925

Family and domain databases

InterProiView protein in InterPro
IPR008081 Cytoplasmic_FMR1-int
IPR009828 DUF1394
PANTHERiPTHR12195 PTHR12195, 2 hits
PfamiView protein in Pfam
PF07159 DUF1394, 1 hit
PF05994 FragX_IP, 1 hit
PIRSFiPIRSF008153 FMR1_interacting, 2 hits
PRINTSiPR01698 CYTOFMRPINTP

Sequencei

Sequence statusi: Complete.

E7EVJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTHVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSIMYQA NFDTNFEDRN
60 70 80 90 100
AFVTGIARYI EQATVHSSMV KCNEQPNRVE IYEKTVEVLE PEVTKLMKFM
110 120 130 140 150
YFQRKAIERF CSEVKRLCHA ERRKDFVSEA YLLTLGKFIN MFAVLDELKN
160 170 180 190 200
MKCSVKNDHS AYKRAAQFLR KMADPQSIQE SQNLSMFLAN HNRITQCLHQ
210 220 230 240 250
QLEVIPGYEE LLADIVNICV DYYENKMYLT PSEKHMLLKV MGFGLYLMDG
260 270 280 290 300
NVSNIYKLDA KKRINLSKID KFFKQLQVVP LFGDMQIELA RYIKTSAHYE
310 320 330 340 350
ENKSKWTCTQ SSISPQYNIC EQMVQIRDDH IRFISELARY SNSEVVTGSG
360 370 380 390 400
LDSQKSDEEY RELFDLALRG LQLLSKWSAH VMEVYSWKLV HPTDKFCNKD
410 420 430 440 450
CPGTAEEYER ATRYNYTSEE KFAFVEVIAM IKGLQVLMGR MESVFNQAIR
460 470 480 490 500
NTIYAALQDF AQVTLREPLR QAVRKKKNVL ISVLQAIRKT ICDWEGGREP
510 520 530 540 550
PNDPCLRGEK DPKGGFDIKV PRRAVGPSST QLYMVRTMLE SLIADKSGSK
560 570 580 590 600
KTLRSSLDGP IVLAIEDFHK QSFFFTHLLN ISEALQQCCD LSQLWFREFF
610 620 630 640 650
LELTMGRRIQ FPIEMSMPWI LTDHILETKE PSMMEYVLYP LDLYNDSAYY
660 670 680 690 700
ALTKFKKQFL YDEIEAEVNL CFDQFVYKLA DQIFAYYKAM AGSVLLDKRF
710 720 730 740 750
RAECKNYGVI IPYPPSNRYE TLLKQRHVQL LGRSIDLNRL ITQRISAAMY
760 770 780 790 800
KSLDQAISRF ESEDLTSIVE LEWLLEINRL THRLLCKHMT LDSFDAMFRE
810 820 830 840 850
ANHNVSAPYG RITLHVFWEL NFDFLPNYCY NGSTNRFVRT AIPFTQEPQR
860 870 880 890 900
DKPANVQPYY LYGSKPLNIA YSHIYSSYRN FVGPPHFKTI CRLLGYQGIA
910 920 930 940 950
VVMEELLKIV KSLLQGTILQ YVKTLIEVMP KICRLPRHEY GSPGILEFFH
960 970 980 990 1000
HQLKDIIEYA ELKTDVFQSL REVGNAILFC LLIEQALSQE EVCDLLHAAP
1010 1020 1030 1040 1050
FQNILPRVYI KEGERLEVRM KRLEAKYAPL HLVPLIERLG TPQQIAIARE
1060 1070 1080 1090 1100
GDLLTKERLC CGLSMFEVIL TRIRSYLQDP IWRGPPPTNG VMHVDECVEF
1110 1120 1130 1140 1150
HRLWSAMQFV YCIPVGTNEF TAEQCFGDGL NWAGCSIIVL LGQQRRFDLF
1160 1170 1180 1190 1200
DFCYHLLKVQ RQDGKDEIIK NVPLKKMADR IRKYQILNNE VFAILNKYMK
1210 1220
SVETDSSTVE HVRCFQPPIH QSLATTC
Length:1,227
Mass (Da):142,577
Last modified:March 8, 2011 - v1
Checksum:i497CC1C4B258515C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008676 Genomic DNA No translation available.
AC009185 Genomic DNA No translation available.
AC016571 Genomic DNA No translation available.
KF459628 Genomic DNA No translation available.
KF510898 Genomic DNA No translation available.
RefSeqiNP_001278650.1, NM_001291721.1
UniGeneiHs.519702

Genome annotation databases

EnsembliENST00000521420; ENSP00000430904; ENSG00000055163
GeneIDi26999
UCSCiuc011ddn.3 human

Similar proteinsi

Entry informationi

Entry nameiE7EVJ5_HUMAN
AccessioniPrimary (citable) accession number: E7EVJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 18, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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