UniProtKB - E7EV34 (E7EV34_HUMAN)
Protein
Submitted name:
Tripeptidyl-peptidase 1
Gene
TPP1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Tripeptidyl-peptidase 1Imported |
Gene namesi | Name:TPP1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000166340.14 |
HGNCi | HGNC:2073, TPP1 |
Expressioni
Gene expression databases
Bgeei | ENSG00000166340, Expressed in right adrenal gland cortex and 225 other tissues |
ExpressionAtlasi | E7EV34, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 120 | Pro-kuma_activInterPro annotationAdd BLAST | 120 |
Phylogenomic databases
GeneTreei | ENSGT00390000008684 |
HOGENOMi | CLU_1668769_0_0_1 |
Family and domain databases
CDDi | cd11377, Pro-peptidase_S53, 1 hit |
Gene3Di | 3.40.50.200, 1 hit |
InterProi | View protein in InterPro IPR036852, Peptidase_S8/S53_dom_sf IPR015366, S53_propep |
Pfami | View protein in Pfam PF09286, Pro-kuma_activ, 1 hit |
SMARTi | View protein in SMART SM00944, Pro-kuma_activ, 1 hit |
SUPFAMi | SSF52743, SSF52743, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All
E7EV34-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XAVSDPSSPQ YGKYLTLENV ADLVRPSPLT LHTVQKWLLA AGAQKCHSVI
60 70 80 90 100
TQDFLTCWLS IRQAELLLPG AEFHHYVGGP TETHVVRSPH PYQLPQALAP
110 120 130 140 150
HVDFGDSGAG CWSVSGRHQF RPTFPASSPY VTTVGGTSFQ EPFLITNEIV
160 170
DYISGGGFSN VFPRPSYQEE
Computationally mapped potential isoform sequencesi
There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO14773 | TPP1_HUMAN | Tripeptidyl-peptidase 1 | TPP1 CLN2, GIG1, UNQ267/PRO304 | 563 | Annotation score: | ||
A0A2R8YGD1 | A0A2R8YGD1_HUMAN | Tripeptidyl aminopeptidase | TPP1 | 470 | Annotation score: | ||
A0A2R8Y7U1 | A0A2R8Y7U1_HUMAN | Tripeptidyl aminopeptidase | TPP1 | 400 | Annotation score: | ||
A0A2R8YD45 | A0A2R8YD45_HUMAN | Tripeptidyl-peptidase 1 | TPP1 | 500 | Annotation score: | ||
A0A2R8YE64 | A0A2R8YE64_HUMAN | Tripeptidyl-peptidase 1 | TPP1 | 162 | Annotation score: | ||
A0A2R8YCK4 | A0A2R8YCK4_HUMAN | Tripeptidyl-peptidase 1 | TPP1 | 81 | Annotation score: | ||
A0A2R8Y7I4 | A0A2R8Y7I4_HUMAN | Tripeptidyl-peptidase 1 | TPP1 | 162 | Annotation score: | ||
E9PME9 | E9PME9_HUMAN | Tripeptidyl-peptidase 1 | TPP1 | 30 | Annotation score: | ||
E9PPA4 | E9PPA4_HUMAN | Tripeptidyl-peptidase 1 | TPP1 | 39 | Annotation score: | ||
A0A2R8YD72 | A0A2R8YD72_HUMAN | Tripeptidyl-peptidase 1 | TPP1 | 92 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 170 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC091564 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000436873; ENSP00000398136; ENSG00000166340 |
UCSCi | uc057ynl.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC091564 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | E7EV34 |
PRIDEi | E7EV34 |
ProteomicsDBi | 18559 |
Protocols and materials databases
Antibodypediai | 23932, 410 antibodies |
Genome annotation databases
Ensembli | ENST00000436873; ENSP00000398136; ENSG00000166340 |
UCSCi | uc057ynl.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000166340.14 |
HGNCi | HGNC:2073, TPP1 |
OpenTargetsi | ENSG00000166340 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000008684 |
HOGENOMi | CLU_1668769_0_0_1 |
Miscellaneous databases
ChiTaRSi | TPP1, human |
Gene expression databases
Bgeei | ENSG00000166340, Expressed in right adrenal gland cortex and 225 other tissues |
ExpressionAtlasi | E7EV34, baseline and differential |
Family and domain databases
CDDi | cd11377, Pro-peptidase_S53, 1 hit |
Gene3Di | 3.40.50.200, 1 hit |
InterProi | View protein in InterPro IPR036852, Peptidase_S8/S53_dom_sf IPR015366, S53_propep |
Pfami | View protein in Pfam PF09286, Pro-kuma_activ, 1 hit |
SMARTi | View protein in SMART SM00944, Pro-kuma_activ, 1 hit |
SUPFAMi | SSF52743, SSF52743, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E7EV34_HUMAN | |
Accessioni | E7EV34Primary (citable) accession number: E7EV34 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 8, 2011 |
Last sequence update: | June 20, 2018 | |
Last modified: | August 12, 2020 | |
This is version 61 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |