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Entry version 77 (02 Jun 2021)
Sequence version 1 (08 Mar 2011)
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Protein
Submitted name:

SH3 and multiple ankyrin repeat domains protein 2

Gene

SHANK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SH3 and multiple ankyrin repeat domains protein 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SHANK2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14295, SHANK2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000162105.16

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, SynapseARBA annotation

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000162105

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
E7EUA2

PRoteomics IDEntifications database

More...
PRIDEi
E7EUA2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
18387

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000162105, Expressed in dorsolateral prefrontal cortex and 198 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E7EUA2, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 131PDZInterPro annotationAdd BLAST95
Domaini1190 – 1253SAMInterPro annotationAdd BLAST64

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni136 – 155DisorderedSequence analysisAdd BLAST20
Regioni282 – 314DisorderedSequence analysisAdd BLAST33
Regioni374 – 394DisorderedSequence analysisAdd BLAST21
Regioni417 – 697DisorderedSequence analysisAdd BLAST281
Regioni732 – 775DisorderedSequence analysisAdd BLAST44
Regioni836 – 930DisorderedSequence analysisAdd BLAST95
Regioni978 – 998DisorderedSequence analysisAdd BLAST21
Regioni1082 – 1180DisorderedSequence analysisAdd BLAST99

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi288 – 312Pro residuesSequence analysisAdd BLAST25
Compositional biasi439 – 459Polar residuesSequence analysisAdd BLAST21
Compositional biasi574 – 603Polar residuesSequence analysisAdd BLAST30
Compositional biasi676 – 697Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi732 – 747Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi844 – 873Polar residuesSequence analysisAdd BLAST30
Compositional biasi907 – 930Polar residuesSequence analysisAdd BLAST24
Compositional biasi980 – 994Pro residuesSequence analysisAdd BLAST15
Compositional biasi1082 – 1120Polar residuesSequence analysisAdd BLAST39
Compositional biasi1129 – 1149Polar residuesSequence analysisAdd BLAST21
Compositional biasi1164 – 1180Polar residuesSequence analysisAdd BLAST17

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153561

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001824_0_0_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 1 hit
2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001478, PDZ
IPR041489, PDZ_6
IPR036034, PDZ_sf
IPR001660, SAM
IPR013761, SAM/pointed_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17820, PDZ_6, 1 hit
PF00536, SAM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228, PDZ, 1 hit
SM00454, SAM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769, SSF47769, 1 hit
SSF50156, SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106, PDZ, 1 hit
PS50105, SAM_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

E7EUA2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMNVPGGGAA AVMMTGYNNG RCPRNSLYSD CIIEEKTVVL QKKDNEGFGF
60 70 80 90 100
VLRGAKADTP IEEFTPTPAF PALQYLESVD EGGVAWQAGL RTGDFLIEVN
110 120 130 140 150
NENVVKVGHR QVVNMIRQGG NHLVLKVVTV TRNLDPDDTA RKKAPPPPKR
160 170 180 190 200
APTTALTLRS KSMTSELEEL VDKDKPEEIV PASKPSRAAE NMAVEPRVAT
210 220 230 240 250
IKQRPSSRCF PAGSDMNSVY ERQGIAVMTP TVPGSPKAPF LGIPRGTMRR
260 270 280 290 300
QKSIDSRIFL SGITEEERQF LAPPMLKFTR SLSMPDTSED IPPPPQSVPP
310 320 330 340 350
SPPPPSPTTY NCPKSPTPRV YGTIKPAFNQ NSAAKVSPAT RSDTVATMMR
360 370 380 390 400
EKGMYFRREL DRYSLDSEDL YSRNAGPQAN FRNKRGQMPE NPYSEVGKIA
410 420 430 440 450
SKAVYVPAKP ARRKGMLVKQ SNVEDSPEKT CSIPIPTIIV KEPSTSSSGK
460 470 480 490 500
SSQGSSMEID PQAPEPPSQL RPDESLTVSS PFAAAIAGAV RDREKRLEAR
510 520 530 540 550
RNSPAFLSTD LGDEDVGLGP PAPRTRPSMF PEEGDFADED SAEQLSSPMP
560 570 580 590 600
SATPREPENH FVGGAEASAP GEAGRPLNST SKAQGPESSP AVPSASSGTA
610 620 630 640 650
GPGNYVHPLT GRLLDPSSPL ALALSARDRA MKESQQGPKG EAPKADLNKP
660 670 680 690 700
LYIDTKMRPS LDAGFPTVTR QNTRGPLRRQ ETENKYETDL GRDRKGDDKK
710 720 730 740 750
NMLIDIMDTS QQKSAGLLMV HTVDATKLDN ALQEEDEKAE VEMKPDSSPS
760 770 780 790 800
EVPEGVSETE GALQISAAPE PTTVPGRTIV AVGSMEEAVI LPFRIPPPPL
810 820 830 840 850
ASVDLDEDFI FTEPLPPPLE FANSFDIPDD RAASVPALSD LVKQKKSDTP
860 870 880 890 900
QSPSLNSSQP TNSADSKKPA SLSNCLPASF LPPPESFDAV ADSGIEEVDS
910 920 930 940 950
RSSSDHHLET TSTISTVSSI STLSSEGGEN VDTCTVYADG QAFMVDKPPV
960 970 980 990 1000
PPKPKMKPII HKSNALYQDA LVEEDVDSFV IPPPAPPPPP GSAQPGMAKV
1010 1020 1030 1040 1050
LQPRTSKLWG DVTEIKSPIL SGPKANVISE LNSILQQMNR EKLAKPGEGL
1060 1070 1080 1090 1100
DSPMGAKSAS LAPRSPEIMS TISGTRSTTV TFTVRPGTSQ PITLQSRPPD
1110 1120 1130 1140 1150
YESRTSGTRR APSPVVSPTE MNKETLPAPL SAATASPSPA LSDVFSLPSQ
1160 1170 1180 1190 1200
PPSGDLFGLN PAGRSRSPSP SILQQPISNK PFTTKPVHLW TKPDVADWLE
1210 1220 1230 1240 1250
SLNLGEHKEA FMDNEIDGSH LPNLQKEDLI DLGVTRVGHR MNIERALKQL

LDR
Length:1,253
Mass (Da):134,800
Last modified:March 8, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i08D46578C3E26C21
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UPX8SHAN2_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2 CORTBP1, KIAA1022, PROSAP1
1,470Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A6NHU9A6NHU9_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
1,261Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MSQ6A0A0A0MSQ6_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
1,261Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A590UJ45A0A590UJ45_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
1,279Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C1X5H7C1X5_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
1,128Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JFP8C9JFP8_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A590UJF3A0A590UJF3_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
817Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EX50E7EX50_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
244Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y7S5H0Y7S5_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
257Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X158A0A087X158_HUMAN
SH3 and multiple ankyrin repeat dom...
SHANK2
258Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC234421 Genomic DNA No translation available.
AP000590 Genomic DNA No translation available.
AP001271 Genomic DNA No translation available.
AP001648 Genomic DNA No translation available.
AP003783 Genomic DNA No translation available.
AP003967 Genomic DNA No translation available.
AP004370 Genomic DNA No translation available.
AP005401 Genomic DNA No translation available.
KF455409 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000409161; ENSP00000386491; ENSG00000162105

UCSC genome browser

More...
UCSCi
uc001opz.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC234421 Genomic DNA No translation available.
AP000590 Genomic DNA No translation available.
AP001271 Genomic DNA No translation available.
AP001648 Genomic DNA No translation available.
AP003783 Genomic DNA No translation available.
AP003967 Genomic DNA No translation available.
AP004370 Genomic DNA No translation available.
AP005401 Genomic DNA No translation available.
KF455409 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiE7EUA2
PRIDEiE7EUA2
ProteomicsDBi18387

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2161, 305 antibodies

Genome annotation databases

EnsembliENST00000409161; ENSP00000386491; ENSG00000162105
UCSCiuc001opz.4, human

Organism-specific databases

HGNCiHGNC:14295, SHANK2
OpenTargetsiENSG00000162105
VEuPathDBiHostDB:ENSG00000162105.16

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000153561
HOGENOMiCLU_001824_0_0_1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SHANK2, human

Gene expression databases

BgeeiENSG00000162105, Expressed in dorsolateral prefrontal cortex and 198 other tissues
ExpressionAtlasiE7EUA2, baseline and differential

Family and domain databases

Gene3Di1.10.150.50, 1 hit
2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR001478, PDZ
IPR041489, PDZ_6
IPR036034, PDZ_sf
IPR001660, SAM
IPR013761, SAM/pointed_sf
PfamiView protein in Pfam
PF17820, PDZ_6, 1 hit
PF00536, SAM_1, 1 hit
SMARTiView protein in SMART
SM00228, PDZ, 1 hit
SM00454, SAM, 1 hit
SUPFAMiSSF47769, SSF47769, 1 hit
SSF50156, SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106, PDZ, 1 hit
PS50105, SAM_DOMAIN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7EUA2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7EUA2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: June 2, 2021
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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