UniProtKB - E7ETT1 (E7ETT1_HUMAN)
Protein
Submitted name:
Propionyl-CoA carboxylase beta chain, mitochondrial
Gene
PCCB
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ligase activity Source: UniProtKB-KW
Keywordsi
Molecular function | LigaseARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Propionyl-CoA carboxylase beta chain, mitochondrialImported |
Gene namesi | Name:PCCBImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000114054.13 |
HGNCi | HGNC:8654, PCCB |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5003219496 | 24 – 520 | Sequence analysisAdd BLAST | 497 |
Proteomic databases
MaxQBi | E7ETT1 |
PeptideAtlasi | E7ETT1 |
PRIDEi | E7ETT1 |
ProteomicsDBi | 18283 |
Expressioni
Gene expression databases
Bgeei | ENSG00000114054, Expressed in right adrenal gland and 238 other tissues |
ExpressionAtlasi | E7ETT1, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 32 – 271 | CoA carboxyltransferase N-terminalInterPro annotationAdd BLAST | 240 | |
Domaini | 275 – 514 | CoA carboxyltransferase C-terminalInterPro annotationAdd BLAST | 240 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000157741 |
Family and domain databases
InterProi | View protein in InterPro IPR034733, AcCoA_carboxyl IPR029045, ClpP/crotonase-like_dom_sf IPR011763, COA_CT_C IPR011762, COA_CT_N |
Pfami | View protein in Pfam PF01039, Carboxyl_trans, 1 hit |
SUPFAMi | SSF52096, SSF52096, 2 hits |
PROSITEi | View protein in PROSITE PS50989, COA_CT_CTER, 1 hit PS50980, COA_CT_NTER, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All
E7ETT1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAALRVAAV GARLSVLASG LRAAVRSLCS QATSVNERIE NKRRTALLGG
60 70 80 90 100
GQRRIDAQHK RGKLTARERI SLLLDPGSFV ESDMFVEHRC ADFGMAADKN
110 120 130 140 150
KFPGDSVVTG RGRINGRLVY VFSQIMDQAI TVGAPVIGLN DSGGARIQEG
160 170 180 190 200
VESLAGYADI FLRNVTASGV IPQISLIMGP CAGGAVYSPA LTDFTFMVKD
210 220 230 240 250
TSYLFITGPD VVKSVTNEDV TQEELGGAKT HTTMSGVAHR AFENDVDALC
260 270 280 290 300
NLRDFFNYLP LSSQDPAPVR ECHDPSDRLV PELDTIVPLE STKAYNMVDI
310 320 330 340 350
IHSVVDEREF FEIMPNYAKN IIVGFARMNG RTVGIVGNQP KVASGCLDIN
360 370 380 390 400
SSVKGARFVR FCDAFNIPLI TFVDVPGFLP GTAQEYGGII RHGAKLLYAF
410 420 430 440 450
AEATVPKVTV ITRKAYGGAY DVMSSKHLCG DTNYAWPTAE IAVMGAKGAV
460 470 480 490 500
EIIFKGHENV EAAQAEYIEK FANPFPAAVR GFVDDIIQPS STRARICCDL
510 520
DVLASKKVQR PWRKHANIPL
Computationally mapped potential isoform sequencesi
There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP05166 | PCCB_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 539 | Annotation score: | ||
H7C5C9 | H7C5C9_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 163 | Annotation score: | ||
C9JVW9 | C9JVW9_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 133 | Annotation score: | ||
E7EX59 | E7EX59_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 570 | Annotation score: | ||
E7ENC1 | E7ENC1_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 303 | Annotation score: | ||
C9JQS9 | C9JQS9_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 559 | Annotation score: | ||
E7EUY3 | E7EUY3_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 516 | Annotation score: | ||
E9PEC3 | E9PEC3_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 423 | Annotation score: | ||
C9JVY9 | C9JVY9_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 191 | Annotation score: | ||
E7ETT4 | E7ETT4_HUMAN | Propionyl-CoA carboxylase beta chai... | PCCB | 482 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC069524 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000483687; ENSP00000420639; ENSG00000114054 |
UCSCi | uc062oda.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC069524 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | E7ETT1 |
PeptideAtlasi | E7ETT1 |
PRIDEi | E7ETT1 |
ProteomicsDBi | 18283 |
Protocols and materials databases
Antibodypediai | 33408, 198 antibodies |
Genome annotation databases
Ensembli | ENST00000483687; ENSP00000420639; ENSG00000114054 |
UCSCi | uc062oda.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000114054.13 |
HGNCi | HGNC:8654, PCCB |
OpenTargetsi | ENSG00000114054 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157741 |
Miscellaneous databases
ChiTaRSi | PCCB, human |
Gene expression databases
Bgeei | ENSG00000114054, Expressed in right adrenal gland and 238 other tissues |
ExpressionAtlasi | E7ETT1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR034733, AcCoA_carboxyl IPR029045, ClpP/crotonase-like_dom_sf IPR011763, COA_CT_C IPR011762, COA_CT_N |
Pfami | View protein in Pfam PF01039, Carboxyl_trans, 1 hit |
SUPFAMi | SSF52096, SSF52096, 2 hits |
PROSITEi | View protein in PROSITE PS50989, COA_CT_CTER, 1 hit PS50980, COA_CT_NTER, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E7ETT1_HUMAN | |
Accessioni | E7ETT1Primary (citable) accession number: E7ETT1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 8, 2011 |
Last sequence update: | March 8, 2011 | |
Last modified: | October 7, 2020 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |