UniProtKB - E7ETI4 (E7ETI4_HUMAN)
Protein
Submitted name:
AF4/FMR2 family member 1
Gene
AFF1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: AF4/FMR2 family member 1Imported |
Gene namesi | Name:AFF1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:7135, AFF1 |
VEuPathDBi | HostDB:ENSG00000172493.20 |
PTM / Processingi
Proteomic databases
MaxQBi | E7ETI4 |
PeptideAtlasi | E7ETI4 |
PRIDEi | E7ETI4 |
ProteomicsDBi | 18213 |
Expressioni
Gene expression databases
Bgeei | ENSG00000172493, Expressed in placenta and 259 other tissues |
ExpressionAtlasi | E7ETI4, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 80 – 321 | DisorderedSequence analysisAdd BLAST | 242 | |
Regioni | 373 – 406 | DisorderedSequence analysisAdd BLAST | 34 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 106 – 142 | PolarSequence analysisAdd BLAST | 37 | |
Compositional biasi | 175 – 198 | PolyampholyteSequence analysisAdd BLAST | 24 | |
Compositional biasi | 220 – 248 | PolarSequence analysisAdd BLAST | 29 | |
Compositional biasi | 377 – 406 | PolarSequence analysisAdd BLAST | 30 |
Phylogenomic databases
GeneTreei | ENSGT00950000182974 |
HOGENOMi | CLU_049694_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR007797, AF4/FMR2 |
PANTHERi | PTHR10528, PTHR10528, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
E7ETI4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAFTERVNSS GNSLYNDDRN LLRIREKERR NQEAHQEKEA FPEKIPLFGE
60 70 80 90 100
PYKTAKGDEL SSRIQNMLGN YEEVKEFLST KSHTHRLDAS ENRLGKPKYP
110 120 130 140 150
LIPDKGSSIP SSSFHTSVHH QSIHTPASGP LSVGNISHNP KMAQPRTEPM
160 170 180 190 200
PSLHAKSCGP PDSQHLTQDR LGQEGFGSSH HKKGDRRADG DHCASVTDSA
210 220 230 240 250
PERELSPLIS LPSPVPPLSP IHSNQQTLPR TQGSSKVHGS SNNSKGYCPA
260 270 280 290 300
KSPKDLAVKV HDKETPQDSL VAPAQPPSQT FPPPSLPSKS VAMQQKPTAY
310 320 330 340 350
VRPMDGQDQA PSESPELKPL PEDYRQQTFE KTDLKVPAKA KLTKLKMPSQ
360 370 380 390 400
SVETYSNEVH CVEEILKEMT HSWPPPLTAI HTPSTAEPSK FPFPTKDSQH
VSSVTQ
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP51825 | AFF1_HUMAN | AF4/FMR2 family member 1 | AFF1 AF4, FEL, MLLT2, PBM1 | 1,210 | Annotation score: | ||
F5GXF9 | F5GXF9_HUMAN | AF4/FMR2 family member 1 | AFF1 | 1,205 | Annotation score: | ||
A0A669KBI3 | A0A669KBI3_HUMAN | AF4/FMR2 family member 1 | AFF1 | 1,075 | Annotation score: | ||
H0Y9S4 | H0Y9S4_HUMAN | AF4/FMR2 family member 1 | AFF1 | 194 | Annotation score: | ||
D6RAU0 | D6RAU0_HUMAN | AF4/FMR2 family member 1 | AFF1 | 137 | Annotation score: | ||
D6RIZ5 | D6RIZ5_HUMAN | AF4/FMR2 family member 1 | AFF1 | 52 | Annotation score: | ||
E7EMC5 | E7EMC5_HUMAN | AF4/FMR2 family member 1 | AFF1 | 417 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 406 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092658 Genomic DNA No translation available. AC093779 Genomic DNA No translation available. AC093827 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000507468; ENSP00000427593; ENSG00000172493 |
UCSCi | uc062xzx.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092658 Genomic DNA No translation available. AC093779 Genomic DNA No translation available. AC093827 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | E7ETI4 |
PeptideAtlasi | E7ETI4 |
PRIDEi | E7ETI4 |
ProteomicsDBi | 18213 |
Protocols and materials databases
Antibodypediai | 25387, 256 antibodies |
Genome annotation databases
Ensembli | ENST00000507468; ENSP00000427593; ENSG00000172493 |
UCSCi | uc062xzx.1, human |
Organism-specific databases
HGNCi | HGNC:7135, AFF1 |
OpenTargetsi | ENSG00000172493 |
VEuPathDBi | HostDB:ENSG00000172493.20 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00950000182974 |
HOGENOMi | CLU_049694_0_0_1 |
Miscellaneous databases
ChiTaRSi | AFF1, human |
Gene expression databases
Bgeei | ENSG00000172493, Expressed in placenta and 259 other tissues |
ExpressionAtlasi | E7ETI4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR007797, AF4/FMR2 |
PANTHERi | PTHR10528, PTHR10528, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E7ETI4_HUMAN | |
Accessioni | E7ETI4Primary (citable) accession number: E7ETI4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 8, 2011 |
Last sequence update: | March 8, 2011 | |
Last modified: | April 7, 2021 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |