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Protein
Submitted name:

Nucleoside diphosphate kinase A

Gene

NME1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleoside diphosphate kinase AImported
Gene namesi
Name:NME1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000239672.7
HGNCiHGNC:7849 NME1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000239672

PTM / Processingi

Proteomic databases

MaxQBiE7ERL0
PeptideAtlasiE7ERL0
PRIDEiE7ERL0

Expressioni

Gene expression databases

BgeeiENSG00000239672 Expressed in 111 organ(s), highest expression level in left adrenal gland
ExpressionAtlasiE7ERL0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7ERL0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 139NDKInterPro annotationAdd BLAST111

Sequence similaritiesi

Belongs to the NDK family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0888 Eukaryota
COG0105 LUCA
GeneTreeiENSGT00760000119146

Family and domain databases

Gene3Di3.30.70.141, 1 hit
InterProiView protein in InterPro
IPR034907 NDK-like_dom
IPR036850 NDK-like_dom_sf
IPR001564 Nucleoside_diP_kinase
PfamiView protein in Pfam
PF00334 NDK, 1 hit
PRINTSiPR01243 NUCDPKINASE
SMARTiView protein in SMART
SM00562 NDK, 1 hit
SUPFAMiSSF54919 SSF54919, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.iShow all

E7ERL0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLLSTLGIV FQGEGPPISS CDTGTMANCE RTFIAIKPDG VQRGLVGEII
60 70 80 90 100
KRFEQKGFRL VGLKFMQASE DLLKEHYVDL KDRPFFAGLV KYMHSGPVVA
110 120 130
MVWEGLNVVK TGRVMLGETN PADSKPGTIR GDFCIQVGR
Length:139
Mass (Da):15,261
Last modified:March 8, 2011 - v1
Checksum:iE8610FA62DB9305D
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P15531NDKA_HUMAN
Nucleoside diphosphate kinase A
NME1 NDPKA, NM23
152Annotation score:
E5RHP0E5RHP0_HUMAN
Nucleoside diphosphate kinase A
NME1
82Annotation score:
C9K028C9K028_HUMAN
Nucleoside diphosphate kinase A
NME1
60Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005839 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000480143; ENSP00000429318; ENSG00000239672
UCSCiuc060hof.1 human

Similar proteinsi

Entry informationi

Entry nameiE7ERL0_HUMAN
AccessioniPrimary (citable) accession number: E7ERL0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 12, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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