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Entry version 80 (07 Oct 2020)
Sequence version 2 (28 Jun 2011)
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Protein

Protein-tyrosine-phosphatase

Gene

PTPRM

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphataseARBA annotation, ReceptorARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein-tyrosine-phosphataseARBA annotation (EC:3.1.3.48ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PTPRMImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000173482.16

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9675, PTPRM

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei681 – 702HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000173482

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

GlycoproteinARBA annotation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E7EPS8

PRoteomics IDEntifications database

More...
PRIDEi
E7EPS8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
17431

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173482, Expressed in visceral pleura and 234 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E7EPS8, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 122MAMInterPro annotationAdd BLAST122
Domaini124 – 215Ig-likeInterPro annotationAdd BLAST92
Domaini222 – 317Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini320 – 418Fibronectin type-IIIInterPro annotationAdd BLAST99
Domaini420 – 525Fibronectin type-IIIInterPro annotationAdd BLAST106
Domaini838 – 1092Tyrosine-protein phosphataseInterPro annotationAdd BLAST255
Domaini1009 – 1083TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75
Domaini1124 – 1386Tyrosine-protein phosphataseInterPro annotationAdd BLAST263
Domaini1300 – 1377TYR_PHOSPHATASE_2InterPro annotationAdd BLAST78

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.ARBA annotation

Keywords - Domaini

Immunoglobulin domainARBA annotation, RepeatARBA annotation, SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155020

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001645_0_1_1

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 3 hits
cd06263, MAM, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 4 hits
3.90.190.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR013151, Immunoglobulin
IPR000998, MAM_dom
IPR029021, Prot-tyrosine_phosphatase-like
IPR000242, PTPase_domain
IPR041201, PTPRJ_TM
IPR016130, Tyr_Pase_AS
IPR003595, Tyr_Pase_cat
IPR000387, TYR_PHOSPHATASE_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041, fn3, 2 hits
PF00047, ig, 1 hit
PF00629, MAM, 1 hit
PF18861, PTP_tm, 1 hit
PF00102, Y_phosphatase, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00020, MAMDOMAIN
PR00700, PRTYPHPHTASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060, FN3, 4 hits
SM00409, IG, 1 hit
SM00137, MAM, 1 hit
SM00194, PTPc, 2 hits
SM00404, PTPc_motif, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 1 hit
SSF49265, SSF49265, 2 hits
SSF49899, SSF49899, 1 hit
SSF52799, SSF52799, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 3 hits
PS50835, IG_LIKE, 1 hit
PS00740, MAM_1, 1 hit
PS50060, MAM_2, 1 hit
PS00383, TYR_PHOSPHATASE_1, 2 hits
PS50056, TYR_PHOSPHATASE_2, 2 hits
PS50055, TYR_PHOSPHATASE_PTP, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E7EPS8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSGSFMLVN ASGRPEGQRA HLLLPQLKEN DTHCIDFHYF VSSKSNSPPG
60 70 80 90 100
LLNVYVKVNN GPLGNPIWNI SGDPTRTWNR AELAISTFWP NFYQVIFEVI
110 120 130 140 150
TSGHQGYLAI DEVKVLGHPC TRTPHFLRIQ NVEVNAGQFA TFQCSAIGRT
160 170 180 190 200
VAGDRLWLQG IDVRDAPLKE IKVTSSRRFI ASFNVVNTTK RDAGKYRCMI
210 220 230 240 250
RTEGGVGISN YAELVVKEPP VPIAPPQLAS VGATYLWIQL NANSINGDGP
260 270 280 290 300
IVAREVEYCT ASGSWNDRQP VDSTSYKIGH LDPDTEYEIS VLLTRPGEGG
310 320 330 340 350
TGSPGPALRT RTKCADPMRG PRKLEVVEVK SRQITIRWEP FGYNVTRCHS
360 370 380 390 400
YNLTVHYCYQ VGGQEQVREE VSWDTENSHP QHTITNLSPY TNVSVKLILM
410 420 430 440 450
NPEGRKESQE LIVQTDEDLP GAVPTESIQG STFEEKIFLQ WREPTQTYGV
460 470 480 490 500
ITLYEITYKA VSSFDPEIDL SNQSGRVSKL GNETHFLFFG LYPGTTYSFT
510 520 530 540 550
IRASTAKGFG PPATNQFTTK ISAPSMPAYE LETPLNQTDN TVTVMLKPAH
560 570 580 590 600
SRGAPVSVYQ IVVEEERPRR TKKTTEILKC YPVPIHFQNA SLLNSQYYFA
610 620 630 640 650
AEFPADSLQA AQPFTIGDNK TYNGYWNTPL LPYKSYRIYF QAASRANGET
660 670 680 690 700
KIDCVQVATK GAATPKPVPE PEKQTDHTVK IAGVIAGILL FVIIFLGVVL
710 720 730 740 750
VMKKRKLAKK RKETMSSTRQ EMTVMVNSMD KSYAEQGTNC DEAFSFMDTH
760 770 780 790 800
NLNGRSVSSP SSFTMKTNTL STSVPNSYYP DETHTMASDT SSLVQSHTYK
810 820 830 840 850
KREPADVPYQ TGQLHPAIRV ADLLQHITQM KCAEGYGFKE EYESFFEGQS
860 870 880 890 900
APWDSAKKDE NRMKNRYGNI IAYDHSRVRL QTIEGDTNSD YINGNYIDGY
910 920 930 940 950
HRPNHYIATQ GPMQETIYDF WRMVWHENTA SIIMVTNLVE VGRVKCCKYW
960 970 980 990 1000
PDDTEIYKDI KVTLIETELL AEYVIRTFAV EKRGVHEIRE IRQFHFTGWP
1010 1020 1030 1040 1050
DHGVPYHATG LLGFVRQVKS KSPPSAGPLV VHCSAGAGRT GCFIVIDIML
1060 1070 1080 1090 1100
DMAEREGVVD IYNCVRELRS RRVNMVQTEE QYVFIHDAIL EACLCGDTSV
1110 1120 1130 1140 1150
PASQVRSLYY DMNKLDPQTN SSQIKEEFRT LNMVTPTLRV EDCSIALLPR
1160 1170 1180 1190 1200
NHEKNRCMDI LPPDRCLPFL ITIDGESSNY INAALMDSYK QPSAFIVTQH
1210 1220 1230 1240 1250
PLPNTVKDFW RLVLDYHCTS VVMLNDVDPA QLCPQYWPEN GVHRHGPIQV
1260 1270 1280 1290 1300
EFVSADLEED IISRIFRIYN AARPQDGYRM VQQFQFLGWP MYRDTPVSKR
1310 1320 1330 1340 1350
SFLKLIRQVD KWQEEYNGGE GRTVVHCLNG GGRSGTFCAI SIVCEMLRHQ
1360 1370 1380 1390
RTVDVFHAVK TLRNNKPNMV DLLDQYKFCY EVALEYLNSG
Length:1,390
Mass (Da):157,075
Last modified:June 28, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF01D7BA023FADF2D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P28827PTPRM_HUMAN
Receptor-type tyrosine-protein phos...
PTPRM PTPRL1
1,452Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KRV2J3KRV2_HUMAN
Receptor-type tyrosine-protein phos...
PTPRM
264Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRB4J3QRB4_HUMAN
Receptor-type tyrosine-protein phos...
PTPRM
207Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KT55J3KT55_HUMAN
Receptor-type tyrosine-protein phos...
PTPRM
238Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q49AC9Q49AC9_HUMAN
PTPRM protein
PTPRM
279Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QLI4J3QLI4_HUMAN
Receptor-type tyrosine-protein phos...
PTPRM
173Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC006566 Genomic DNA No translation available.
AP000897 Genomic DNA No translation available.
AP001091 Genomic DNA No translation available.
AP005118 Genomic DNA No translation available.
AP005227 Genomic DNA No translation available.
AP005900 Genomic DNA No translation available.
KC877688 Genomic DNA No translation available.
KF456345 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000400053; ENSP00000382927; ENSG00000173482

UCSC genome browser

More...
UCSCi
uc060ndp.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006566 Genomic DNA No translation available.
AP000897 Genomic DNA No translation available.
AP001091 Genomic DNA No translation available.
AP005118 Genomic DNA No translation available.
AP005227 Genomic DNA No translation available.
AP005900 Genomic DNA No translation available.
KC877688 Genomic DNA No translation available.
KF456345 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

MaxQBiE7EPS8
PRIDEiE7EPS8
ProteomicsDBi17431

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
21926, 227 antibodies

Genome annotation databases

EnsembliENST00000400053; ENSP00000382927; ENSG00000173482
UCSCiuc060ndp.1, human

Organism-specific databases

EuPathDBiHostDB:ENSG00000173482.16
HGNCiHGNC:9675, PTPRM
OpenTargetsiENSG00000173482

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000155020
HOGENOMiCLU_001645_0_1_1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PTPRM, human

Gene expression databases

BgeeiENSG00000173482, Expressed in visceral pleura and 234 other tissues
ExpressionAtlasiE7EPS8, baseline and differential

Family and domain databases

CDDicd00063, FN3, 3 hits
cd06263, MAM, 1 hit
Gene3Di2.60.40.10, 4 hits
3.90.190.10, 2 hits
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR003599, Ig_sub
IPR013151, Immunoglobulin
IPR000998, MAM_dom
IPR029021, Prot-tyrosine_phosphatase-like
IPR000242, PTPase_domain
IPR041201, PTPRJ_TM
IPR016130, Tyr_Pase_AS
IPR003595, Tyr_Pase_cat
IPR000387, TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00041, fn3, 2 hits
PF00047, ig, 1 hit
PF00629, MAM, 1 hit
PF18861, PTP_tm, 1 hit
PF00102, Y_phosphatase, 2 hits
PRINTSiPR00020, MAMDOMAIN
PR00700, PRTYPHPHTASE
SMARTiView protein in SMART
SM00060, FN3, 4 hits
SM00409, IG, 1 hit
SM00137, MAM, 1 hit
SM00194, PTPc, 2 hits
SM00404, PTPc_motif, 2 hits
SUPFAMiSSF48726, SSF48726, 1 hit
SSF49265, SSF49265, 2 hits
SSF49899, SSF49899, 1 hit
SSF52799, SSF52799, 2 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 3 hits
PS50835, IG_LIKE, 1 hit
PS00740, MAM_1, 1 hit
PS50060, MAM_2, 1 hit
PS00383, TYR_PHOSPHATASE_1, 2 hits
PS50056, TYR_PHOSPHATASE_2, 2 hits
PS50055, TYR_PHOSPHATASE_PTP, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7EPS8_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7EPS8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: June 28, 2011
Last modified: October 7, 2020
This is version 80 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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