Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 76 (02 Jun 2021)
Sequence version 1 (08 Mar 2011)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Filamin-B

Gene

FLNB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Filamin-BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FLNBImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:3755, FLNB

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000136068.14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000136068

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E7EN95

PeptideAtlas

More...
PeptideAtlasi
E7EN95

PRoteomics IDEntifications database

More...
PRIDEi
E7EN95

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
17111

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
E7EN95

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136068, Expressed in tibial nerve and 238 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E7EN95, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 73Calponin-homology (CH)InterPro annotationAdd BLAST73
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati80 – 178FilaminPROSITE-ProRule annotationAdd BLAST99
Repeati180 – 277FilaminPROSITE-ProRule annotationAdd BLAST98
Repeati278 – 374FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati375 – 467FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati471 – 567FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati568 – 670FilaminPROSITE-ProRule annotationAdd BLAST103
Repeati671 – 769FilaminPROSITE-ProRule annotationAdd BLAST99
Repeati770 – 865FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati866 – 958FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati959 – 1053FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati1054 – 1153FilaminPROSITE-ProRule annotationAdd BLAST100
Repeati1154 – 1246FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1247 – 1342FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1343 – 1439FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati1440 – 1535FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1565 – 1623FilaminPROSITE-ProRule annotationAdd BLAST59
Repeati1623 – 1715FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1726 – 1801FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati1804 – 1896FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1894 – 1992FilaminPROSITE-ProRule annotationAdd BLAST99
Repeati1995 – 2087FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati2089 – 2182FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2186 – 2278FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati2314 – 2408FilaminPROSITE-ProRule annotationAdd BLAST95

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24
Regioni75 – 98DisorderedSequence analysisAdd BLAST24

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156286

Identification of Orthologs from Complete Genome Data

More...
OMAi
CTILTPD

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 1 hit
2.60.40.10, 24 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR029874, FLNB
IPR013783, Ig-like_fold
IPR014756, Ig_E-set

The PANTHER Classification System

More...
PANTHERi
PTHR38537:SF7, PTHR38537:SF7, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00630, Filamin, 23 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00557, IG_FLMN, 24 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit
SSF81296, SSF81296, 24 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021, CH, 1 hit
PS50194, FILAMIN_REPEAT, 24 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E7EN95-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQEHSTRRRS LSLCPDWESW DPQKPVDNAR EAMQQADDWL GVPQVITPEE
60 70 80 90 100
IIHPDVDEHS VMTYLSQFPK AKLKPGAPLK PKLNPKKARA YGRGIEPTGN
110 120 130 140 150
MVKQPAKFTV DTISAGQGDV MVFVEDPEGN KEEAQVTPDS DKNKTYSVEY
160 170 180 190 200
LPKVTGLHKV TVLFAGQHIS KSPFEVSVDK AQGDASKVTA KGPGLEAVGN
210 220 230 240 250
IANKPTYFDI YTAGAGVGDI GVEVEDPQGK NTVELLVEDK GNQVYRCVYK
260 270 280 290 300
PMQPGPHVVK IFFAGDTIPK SPFVVQVGEA CNPNACRASG RGLQPKGVRI
310 320 330 340 350
RETTDFKVDT KAAGSGELGV TMKGPKGLEE LVKQKDFLDG VYAFEYYPST
360 370 380 390 400
PGRYSIAITW GGHHIPKSPF EVQVGPEAGM QKVRAWGPGL HGGIVGRSAD
410 420 430 440 450
FVVESIGSEV GSLGFAIEGP SQAKIEYNDQ NDGSCDVKYW PKEPGEYAVH
460 470 480 490 500
IMCDDEDIKD SPYMAFIHPA TGGYNPDLVR AYGPGLEKSG CIVNNLAEFT
510 520 530 540 550
VDPKDAGKAP LKIFAQDGEG QRIDIQMKNR MDGTYACSYT PVKAIKHTIA
560 570 580 590 600
VVWGGVNIPH SPYRVNIGQG SHPQKVKVFG PGVERSGLKA NEPTHFTVDC
610 620 630 640 650
TEAGEGDVSV GIKCDARVLS EDEEDVDFDI IHNANDTFTV KYVPPAAGRY
660 670 680 690 700
TIKVLFASQE IPASPFRVKV DPSHDASKVK AEGPGLSKAG VENGKPTHFT
710 720 730 740 750
VYTKGAGKAP LNVQFNSPLP GDAVKDLDII DNYDYSHTVK YTPTQQGNMQ
760 770 780 790 800
VLVTYGGDPI PKSPFTVGVA APLDLSKIKL NGLENRVEVG KDQEFTVDTR
810 820 830 840 850
GAGGQGKLDV TILSPSRKVV PCLVTPVTGR ENSTAKFIPR EEGLYAVDVT
860 870 880 890 900
YDGHPVPGSP YTVEASLPPD PSKVKAHGPG LEGGLVGKPA EFTIDTKGAG
910 920 930 940 950
TGGLGLTVEG PCEAKIECSD NGDGTCSVSY LPTKPGEYFV NILFEEVHIP
960 970 980 990 1000
GSPFKADIEM PFDPSKVVAS GPGLEHGKVG EAGLLSVDCS EAGPGALGLE
1010 1020 1030 1040 1050
AVSDSGTKAE VSIQNNKDGT YAVTYVPLTA GMYTLTMKYG GELVPHFPAR
1060 1070 1080 1090 1100
VKVEPAVDTS RIKVFGPGIE GKDVFREATT DFTVDSRPLT QVGGDHIKAH
1110 1120 1130 1140 1150
IANPSGASTE CFVTDNADGT YQVEYTPFEK GLHVVEVTYD DVPIPNSPFK
1160 1170 1180 1190 1200
VAVTEGCQPS RVQAQGPGLK EAFTNKPNVF TVVTRGAGIG GLGITVEGPS
1210 1220 1230 1240 1250
ESKINCRDNK DGSCSAEYIP FAPGDYDVNI TYGGAHIPGS PFRVPVKDVV
1260 1270 1280 1290 1300
DPSKVKIAGP GLGSGVRARV LQSFTVDSSK AGLAPLEVRV LGPRGLVEPV
1310 1320 1330 1340 1350
NVVDNGDGTH TVTYTPSQEG PYMVSVKYAD EEIPRSPFKV KVLPTYDASK
1360 1370 1380 1390 1400
VTASGPGLSS YGVPASLPVD FAIDARDAGE GLLAVQITDQ EGKPKRAIVH
1410 1420 1430 1440 1450
DNKDGTYAVT YIPDKTGRYM IGVTYGGDDI PLSPYRIRAT QTGDASKCLA
1460 1470 1480 1490 1500
TGPGIASTVK TGEEVGFVVD AKTAGKGKVT CTVLTPDGTE AEADVIENED
1510 1520 1530 1540 1550
GTYDIFYTAA KPGTYVIYVR FGGVDIPNSP FTVMVTEEAY VPVSDMNGLG
1560 1570 1580 1590 1600
FKPFDLVIPF AVRKGEITGE VHMPSGKTAT PEIVDNKDGT VTVRYAPTEV
1610 1620 1630 1640 1650
GLHEMHIKYM GSHIPESPLQ FYVNYPNSGS VSAYGPGLVY GVANKTATFT
1660 1670 1680 1690 1700
IVTEDAGEGG LDLAIEGPSK AEISCIDNKD GTCTVTYLPT LPGDYSILVK
1710 1720 1730 1740 1750
YNDKHIPGSP FTAKITDDSR RCSQVKLGSA ADFLLDISET DLSSLTASIK
1760 1770 1780 1790 1800
APSGRDEPCL LKRLPNNHIG ISFIPREVGE HLVSIKKNGN HVANSPVSIM
1810 1820 1830 1840 1850
VVQSEIGDAR RAKVYGRGLS EGRTFEMSDF IVDTRDAGYG GISLAVEGPS
1860 1870 1880 1890 1900
KVDIQTEDLE DGTCKVSYFP TVPGVYIVST KFADEHVPGS PFTVKISGEG
1910 1920 1930 1940 1950
RVKESITRTS RAPSVATVGS ICDLNLKIPE INSSDMSAHV TSPSGRVTEA
1960 1970 1980 1990 2000
EIVPMGKNSH CVRFVPQEMG VHTVSVKYRG QHVTGSPFQF TVGPLGEGGA
2010 2020 2030 2040 2050
HKVRAGGPGL ERGEAGVPAE FSIWTREAGA GGLSIAVEGP SKAEITFDDH
2060 2070 2080 2090 2100
KNGSCGVSYI AQEPGNYEVS IKFNDEHIPE SPYLVPVIAP SDDARRLTVM
2110 2120 2130 2140 2150
SLQESGLKVN QPASFAIRLN GAKGKIDAKV HSPSGAVEEC HVSELEPDKY
2160 2170 2180 2190 2200
AVRFIPHENG VHTIDVKFNG SHVVGSPFKV RVGEPGQAGN PALVSAYGTG
2210 2220 2230 2240 2250
LEGGTTGIQS EFFINTTRAG PGTLSVTIEG PSKVKMDCQE TPEGYKVMYT
2260 2270 2280 2290 2300
PMAPGNYLIS VKYGGPNHIV GSPFKAKVTG QRLVSPGSAN ETSSILVESV
2310 2320 2330 2340 2350
TRSSTETCYS AIPKASSDAS KVTSKGAGLS KAFVGQKSSF LVDCSKAGSN
2360 2370 2380 2390 2400
MLLIGVHGPT TPCEEVSMKH VGNQQYNVTY VVKERGDYVL AVKWGEEHIP

GSPFHVTVP
Length:2,409
Mass (Da):256,281
Last modified:March 8, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i62099547AE4BE890
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O75369FLNB_HUMAN
Filamin-B
FLNB FLN1L, FLN3, TABP, TAP
2,602Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C5L4H7C5L4_HUMAN
Filamin-B
FLNB
135Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MT44A0A0A0MT44_HUMAN
Filamin-B
FLNB
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0C4DGA1A0A0C4DGA1_HUMAN
Filamin-B
FLNB
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC114399 Genomic DNA No translation available.
AC137936 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000493452; ENSP00000418510; ENSG00000136068

UCSC genome browser

More...
UCSCi
uc003djm.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114399 Genomic DNA No translation available.
AC137936 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiE7EN95

Proteomic databases

MaxQBiE7EN95
PeptideAtlasiE7EN95
PRIDEiE7EN95
ProteomicsDBi17111

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1496, 268 antibodies

Genome annotation databases

EnsembliENST00000493452; ENSP00000418510; ENSG00000136068
UCSCiuc003djm.3, human

Organism-specific databases

HGNCiHGNC:3755, FLNB
OpenTargetsiENSG00000136068
VEuPathDBiHostDB:ENSG00000136068.14

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000156286
OMAiCTILTPD

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FLNB, human

Gene expression databases

BgeeiENSG00000136068, Expressed in tibial nerve and 238 other tissues
ExpressionAtlasiE7EN95, baseline and differential

Family and domain databases

Gene3Di1.10.418.10, 1 hit
2.60.40.10, 24 hits
InterProiView protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR029874, FLNB
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
PANTHERiPTHR38537:SF7, PTHR38537:SF7, 3 hits
PfamiView protein in Pfam
PF00630, Filamin, 23 hits
SMARTiView protein in SMART
SM00557, IG_FLMN, 24 hits
SUPFAMiSSF47576, SSF47576, 1 hit
SSF81296, SSF81296, 24 hits
PROSITEiView protein in PROSITE
PS50021, CH, 1 hit
PS50194, FILAMIN_REPEAT, 24 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE7EN95_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E7EN95
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: June 2, 2021
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again