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Protein
Submitted name:

Voltage-dependent calcium channel gamma-like subunit

Gene

TMEM37

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent calcium channel gamma-like subunitImported
Gene namesi
Name:TMEM37Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000171227.6
HGNCiHGNC:18216 TMEM37

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 57HelicalSequence analysisAdd BLAST21
Transmembranei102 – 124HelicalSequence analysisAdd BLAST23
Transmembranei136 – 161HelicalSequence analysisAdd BLAST26
Transmembranei167 – 186HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000171227

PTM / Processingi

Proteomic databases

PRIDEiE7EMC0

Expressioni

Gene expression databases

BgeeiENSG00000171227 Expressed in 171 organ(s), highest expression level in kidney epithelium
ExpressionAtlasiE7EMC0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE7EMC0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IE8N Eukaryota
ENOG4111WUN LUCA
GeneTreeiENSGT00390000006225
OMAiQVCEDLH
OrthoDBiEOG091G0ROD
PhylomeDBiE7EMC0

Family and domain databases

InterProiView protein in InterPro
IPR029372 Tmem37
PANTHERiPTHR31767 PTHR31767, 1 hit
PfamiView protein in Pfam
PF15108 TMEM37, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

E7EMC0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRPDCSSDF NSRHFPLGQA QRPLGQRQPR RSFFESFIRT LIITCVALAV
60 70 80 90 100
VLSSVSICDG HWLLAEDRLF GLWHFCTTTN QTICFRDLGQ AHVPGLAVGM
110 120 130 140 150
GLVRSVGALA VVAAIFGLEF LMVSQLCEDK HSQCKWVMGS ILLLVSFVLS
160 170 180 190 200
SGGLLGFVIL LRNQVTLIGF TLMFWCEFTA SFLLFLNAIS GLHINSITHP

WE
Length:202
Mass (Da):22,422
Last modified:March 8, 2011 - v1
Checksum:i8773688B22A32DEC
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8WXS4CCGL_HUMAN
Voltage-dependent calcium channel g...
TMEM37 PR
190Annotation score:
C9J1Q8C9J1Q8_HUMAN
Voltage-dependent calcium channel g...
TMEM37
66Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013275 Genomic DNA No translation available.
RefSeqiXP_011508961.1, XM_011510659.2
UniGeneiHs.26216

Genome annotation databases

EnsembliENST00000409826; ENSP00000387015; ENSG00000171227
GeneIDi140738
UCSCiuc061nie.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013275 Genomic DNA No translation available.
RefSeqiXP_011508961.1, XM_011510659.2
UniGeneiHs.26216

3D structure databases

ProteinModelPortaliE7EMC0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiE7EMC0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409826; ENSP00000387015; ENSG00000171227
GeneIDi140738
UCSCiuc061nie.1 human

Organism-specific databases

CTDi140738
EuPathDBiHostDB:ENSG00000171227.6
HGNCiHGNC:18216 TMEM37
OpenTargetsiENSG00000171227
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IE8N Eukaryota
ENOG4111WUN LUCA
GeneTreeiENSGT00390000006225
OMAiQVCEDLH
OrthoDBiEOG091G0ROD
PhylomeDBiE7EMC0

Miscellaneous databases

ChiTaRSiTMEM37 human
GenomeRNAii140738

Gene expression databases

BgeeiENSG00000171227 Expressed in 171 organ(s), highest expression level in kidney epithelium
ExpressionAtlasiE7EMC0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR029372 Tmem37
PANTHERiPTHR31767 PTHR31767, 1 hit
PfamiView protein in Pfam
PF15108 TMEM37, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE7EMC0_HUMAN
AccessioniPrimary (citable) accession number: E7EMC0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 7, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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