Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Pseudoxanthomonas suwonensis (strain 11-1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei2Nucleophile; for GATase activityUniRule annotation1
Active sitei605For Fru-6P isomerization activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BioCyciPSUW743721:G1GQV-2510-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotationSAAS annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:Psesu_2488Imported
OrganismiPseudoxanthomonas suwonensis (strain 11-1)Imported
Taxonomic identifieri743721 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaePseudoxanthomonas
Proteomesi
  • UP000008632 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedUniRule annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi743721.Psesu_2488

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 218Glutamine amidotransferase type-2InterPro annotationAdd BLAST217
Domaini286 – 426SISInterPro annotationAdd BLAST141
Domaini459 – 600SISInterPro annotationAdd BLAST142

Phylogenomic databases

eggNOGiENOG4105C46 Bacteria
COG0449 LUCA
HOGENOMiHOG000258896
KOiK00820
OMAiGTSHYAG
OrthoDBiPOG091H0061

Family and domain databases

CDDicd05008 SIS_GlmS_GlmD_1, 1 hit
cd05009 SIS_GlmS_GlmD_2, 1 hit
Gene3Di3.60.20.10, 1 hit
HAMAPiMF_00164 GlmS, 1 hit
InterProiView protein in InterPro
IPR017932 GATase_2_dom
IPR035466 GlmS/AgaS_SIS
IPR035490 GlmS/FrlB_SIS
IPR005855 GlmS_trans
IPR029055 Ntn_hydrolases_N
IPR001347 SIS
PANTHERiPTHR10937:SF0 PTHR10937:SF0, 1 hit
PfamiView protein in Pfam
PF01380 SIS, 2 hits
SUPFAMiSSF56235 SSF56235, 1 hit
TIGRFAMsiTIGR01135 glmS, 1 hit
PROSITEiView protein in PROSITE
PS51278 GATASE_TYPE_2, 1 hit
PS51464 SIS, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E6WWB2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCGIVGAIAD RDVVPVLVEG LKRLEYRGYD SSGIAVVDPD SVRRVRRTGR
60 70 80 90 100
VAEMEHAAVH EDFHGVLGIG HTRWATHGGV TEANAHPHIS HGELALVHNG
110 120 130 140 150
IIENHEEQRA RLTSLGYVFE SQTDTEVIAH LIHHHMSSGQ DLLVALQAAV
160 170 180 190 200
KELTGAYALA VVSRREPDRL VGARMGCPLL VGLGEGENFL ASDVSAIISA
210 220 230 240 250
TRRVIFLEEG DTAEIRREGV RVFDGRDQQV QREVHVSDVS LASLELGPYR
260 270 280 290 300
HFMQKEVHEQ PRAIADTVEA VIDAGGFEPT LFGANAEEVL RKVKGVQILA
310 320 330 340 350
CGTSYYAGLT ARYWIEAIAG LPCNVEIASE YRYRDAYADP DYLVVTISQS
360 370 380 390 400
GETLDTMEAL KYARSLGHAH TLSICNVPES AIPRASELVC YTRAGAEIGV
410 420 430 440 450
ASTKAFTTQL AALFQLTVVL GKLHGRVTPE QEAGYLEQLR MLPGSVQHAL
460 470 480 490 500
NLEPQIQAWA ERFAAKQNAL FLGRGLHYPI ALEGALKLKE ISYIHAEAYP
510 520 530 540 550
AGELKHGPLA LVDAAMPVVV IAPNDRLLEK VKSNMQEVRA RGGELFVFAD
560 570 580 590 600
QDSNFTASEG VHVIRTPRHS GVLSPVIHTI PVQLLAYHTA LARGTDVDKP
610
RNLAKSVTVE
Length:610
Mass (Da):66,464
Last modified:March 8, 2011 - v1
Checksum:i4A91679190993169
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002446 Genomic DNA Translation: ADV28320.1
RefSeqiWP_013536147.1, NC_014924.1

Genome annotation databases

EnsemblBacteriaiADV28320; ADV28320; Psesu_2488
KEGGipsu:Psesu_2488

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002446 Genomic DNA Translation: ADV28320.1
RefSeqiWP_013536147.1, NC_014924.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi743721.Psesu_2488

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADV28320; ADV28320; Psesu_2488
KEGGipsu:Psesu_2488

Phylogenomic databases

eggNOGiENOG4105C46 Bacteria
COG0449 LUCA
HOGENOMiHOG000258896
KOiK00820
OMAiGTSHYAG
OrthoDBiPOG091H0061

Enzyme and pathway databases

BioCyciPSUW743721:G1GQV-2510-MONOMER

Family and domain databases

CDDicd05008 SIS_GlmS_GlmD_1, 1 hit
cd05009 SIS_GlmS_GlmD_2, 1 hit
Gene3Di3.60.20.10, 1 hit
HAMAPiMF_00164 GlmS, 1 hit
InterProiView protein in InterPro
IPR017932 GATase_2_dom
IPR035466 GlmS/AgaS_SIS
IPR035490 GlmS/FrlB_SIS
IPR005855 GlmS_trans
IPR029055 Ntn_hydrolases_N
IPR001347 SIS
PANTHERiPTHR10937:SF0 PTHR10937:SF0, 1 hit
PfamiView protein in Pfam
PF01380 SIS, 2 hits
SUPFAMiSSF56235 SSF56235, 1 hit
TIGRFAMsiTIGR01135 glmS, 1 hit
PROSITEiView protein in PROSITE
PS51278 GATASE_TYPE_2, 1 hit
PS51464 SIS, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE6WWB2_PSEUU
AccessioniPrimary (citable) accession number: E6WWB2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: February 28, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again