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Protein

Elongation factor P

Gene

efp

Organism
Neisseria meningitidis serogroup B / serotype 15 (strain H44/76)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Pathwayi: polypeptide chain elongation

This protein is involved in the pathway polypeptide chain elongation, which is part of Protein biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway polypeptide chain elongation and in Protein biosynthesis.

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis

Enzyme and pathway databases

UniPathwayi
UPA00345

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor PUniRule annotation
Short name:
EF-PUniRule annotation
Gene namesi
Name:efpUniRule annotationImported
ORF Names:NMH_0798Imported
OrganismiNeisseria meningitidis serogroup B / serotype 15 (strain H44/76)Imported
Taxonomic identifieri909420 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000032707 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE6MVW0
SMRiE6MVW0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 122EFPInterPro annotationAdd BLAST56
Domaini130 – 185Elong-fact-P_CInterPro annotationAdd BLAST56

Sequence similaritiesi

Belongs to the elongation factor P family.UniRule annotation

Phylogenomic databases

KOiK02356
OMAiFMDNEDY

Family and domain databases

CDDicd04470 S1_EF-P_repeat_1, 1 hit
cd05794 S1_EF-P_repeat_2, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00141 EF_P, 1 hit
InterProiView protein in InterPro
IPR015365 Elong-fact-P_C
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR020599 Transl_elong_fac_P/YeiP
IPR013185 Transl_elong_KOW-like
IPR001059 Transl_elong_P/YeiP_cen
IPR011768 Transl_elongation_fac_P
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30053 PTHR30053, 1 hit
PfamiView protein in Pfam
PF01132 EFP, 1 hit
PF08207 EFP_N, 1 hit
PF09285 Elong-fact-P_C, 1 hit
PIRSFiPIRSF005901 EF-P, 1 hit
SMARTiView protein in SMART
SM01185 EFP, 1 hit
SM00841 Elong-fact-P_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 2 hits
TIGRFAMsiTIGR00038 efp, 1 hit

Sequencei

Sequence statusi: Complete.

E6MVW0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTAQELRAG NVFMVGNDPM VVQKTEYIKG GRSSAKVSMK LKNLLTGAAS
60 70 80 90 100
ETIYKADDKF DVVILSRKNC TYSYFADPMY VFMDEEFNQY EIEADNIGDA
110 120 130 140 150
LKFIVDGMED QCEVTFYEGN PISVELPTII VREVEYTEPA VKGDTSGKVM
160 170 180
KTARLVGGTE IQVMSYIENG DKVEIDTRTG EFRKRA
Length:186
Mass (Da):20,880
Last modified:March 8, 2011 - v1
Checksum:i3502433BE9D8E189
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEQZ01000013 Genomic DNA Translation: EFV64285.1
RefSeqiWP_002219406.1, NZ_AEQZ01000013.1

Genome annotation databases

EnsemblBacteriaiEFV64285; EFV64285; NMH_0798
GeneIDi33952354
KEGGinmh:NMBH4476_1234
PATRICifig|909420.3.peg.1693

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEQZ01000013 Genomic DNA Translation: EFV64285.1
RefSeqiWP_002219406.1, NZ_AEQZ01000013.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5WXKX-ray1.80B1-63[»]
ProteinModelPortaliE6MVW0
SMRiE6MVW0
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEFV64285; EFV64285; NMH_0798
GeneIDi33952354
KEGGinmh:NMBH4476_1234
PATRICifig|909420.3.peg.1693

Phylogenomic databases

KOiK02356
OMAiFMDNEDY

Enzyme and pathway databases

UniPathwayi
UPA00345

Family and domain databases

CDDicd04470 S1_EF-P_repeat_1, 1 hit
cd05794 S1_EF-P_repeat_2, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_00141 EF_P, 1 hit
InterProiView protein in InterPro
IPR015365 Elong-fact-P_C
IPR012340 NA-bd_OB-fold
IPR014722 Rib_L2_dom2
IPR020599 Transl_elong_fac_P/YeiP
IPR013185 Transl_elong_KOW-like
IPR001059 Transl_elong_P/YeiP_cen
IPR011768 Transl_elongation_fac_P
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30053 PTHR30053, 1 hit
PfamiView protein in Pfam
PF01132 EFP, 1 hit
PF08207 EFP_N, 1 hit
PF09285 Elong-fact-P_C, 1 hit
PIRSFiPIRSF005901 EF-P, 1 hit
SMARTiView protein in SMART
SM01185 EFP, 1 hit
SM00841 Elong-fact-P_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 2 hits
TIGRFAMsiTIGR00038 efp, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE6MVW0_NEIMH
AccessioniPrimary (citable) accession number: E6MVW0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: June 20, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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