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UniProtKB - E6D757 (E6D757_CUTAC)

Entry version 48 (31 Jul 2019)
Sequence version 1 (08 Mar 2011)
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Protein
Submitted name:

Putative ATP synthase F0, A subunit

Gene

HMPREF9578_01009

Organism
Cutibacterium acnes HL110PA4
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseSAAS annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		GCF_000144895-HMP:HMPREF9578_RS04985-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative ATP synthase F0, A subunitImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:HMPREF9578_01009Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCutibacterium acnes HL110PA4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri765080 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Actinobacteria › Propionibacteriales › Propionibacteriaceae › Cutibacterium ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000003563 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei316 – 336HelicalSequence analysisAdd BLAST21
Transmembranei373 – 399HelicalSequence analysisAdd BLAST27
Transmembranei411 – 441HelicalSequence analysisAdd BLAST31
Transmembranei453 – 475HelicalSequence analysisAdd BLAST23
Transmembranei487 – 509HelicalSequence analysisAdd BLAST23
Transmembranei529 – 553HelicalSequence analysisAdd BLAST25
Transmembranei574 – 594HelicalSequence analysisAdd BLAST21
Transmembranei637 – 658HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 147PTS EIIA type-2InterPro annotationAdd BLAST144
Domaini180 – 275PTS EIIB type-2InterPro annotationAdd BLAST96
Domaini308 – 668PTS EIIC type-2InterPro annotationAdd BLAST361

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni152 – 171DisorderedSequence analysisAdd BLAST20
Regioni277 – 300DisorderedSequence analysisAdd BLAST24

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Conserved Domains Database

More...CDDi		cd05569 PTS_IIB_fructose, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.930.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016152 PTrfase/Anion_transptr
IPR002178 PTS_EIIA_type-2_dom
IPR036095 PTS_EIIB-like_sf
IPR013011 PTS_EIIB_2
IPR003501 PTS_EIIB_2/3
IPR013014 PTS_EIIC_2
IPR003353 PTS_IIB_fruc
IPR006327 PTS_IIC_fruc

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00359 PTS_EIIA_2, 1 hit
PF02302 PTS_IIB, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52794 SSF52794, 1 hit
SSF55804 SSF55804, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00829 FRU, 1 hit
TIGR01427 PTS_IIC_fructo, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51094 PTS_EIIA_TYPE_2, 1 hit
PS51099 PTS_EIIB_TYPE_2, 1 hit
PS51104 PTS_EIIC_TYPE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E6D757-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTPLITPEL VSLDANLGST KTEVITSVAG LIAAAGRADA DGLAHDTLDR 
        60         70         80         90        100
ESKSPTGMPG GFAIPHCRSA AVSQVSLGFA RLSPAVDFNG PDGPADLIFM 
       110        120        130        140        150
IAASEDGGAD HMKLLTKLAR ALVNPEFVEQ LRQAPDAQTV VDLIGGVVEP 
       160        170        180        190        200
KEEASTSSAT ALPAPGHAAV TNTASDTPRI VAITACPTGI AHTYMAADYL 
       210        220        230        240        250
RAAGKKLGVD VKVEPQGSTA TEPLSTADIE GADAVIFATD VGVKGRERFA 
       260        270        280        290        300
GKPVIESGVK RAVDEPEKMV SEAVAASKDP HAHRVPAGHG EQQEPEQAGS 
       310        320        330        340        350
HIGWGKRIQQ ALMTGVSYMI PFVAAGGLLI ALGFLFGGYE IAKDGMDIAL 
       360        370        380        390        400
HNTFNNLPTP TAHALGGSAT MTYIGAVLFA VGQAAFGFLL PALAGYIGFG 
       410        420        430        440        450
LADRPGIAPG FVAGAVAGVT GAGFIGAIIG GLLGGFVAYW FTRLNPPRWL 
       460        470        480        490        500
RGLMPVVIIP LVGSLVAGGL MYVVLGRPLA ALTNALNNWL GGMSGASAVI 
       510        520        530        540        550
LGIVLGLMMC SDLGGPINKA AYLFATTNLA VTNVGSLKVM AAVMAAGMVP 
       560        570        580        590        600
PLAMALSTTL RPKLYQPAER ENGTAAWLLG ASFISEGAIP FAAADPLRVI 
       610        620        630        640        650
PSMMVGGATT GALSMALGAA SKAPHGGIFV FFAIDRVWAF ILAIVVGTLV 
       660        670
AALLVTALKA SARRKAAAAA
Length:670
Mass (Da):68,217
Last modified:March 8, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1DF7A45D0039BAA8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
ADYF01000059 Genomic DNA Translation: EFT63349.1

NCBI Reference Sequences

More...RefSeqi		WP_002512858.1, NZ_GL384072.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		EFT63349; EFT63349; HMPREF9578_01009

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|765080.3.peg.1301

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADYF01000059 Genomic DNA Translation: EFT63349.1
RefSeqiWP_002512858.1, NZ_GL384072.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiEFT63349; EFT63349; HMPREF9578_01009
PATRICifig|765080.3.peg.1301

Enzyme and pathway databases

BioCyciGCF_000144895-HMP:HMPREF9578_RS04985-MONOMER

Family and domain databases

CDDicd05569 PTS_IIB_fructose, 1 hit
Gene3Di3.40.930.10, 1 hit
InterProiView protein in InterPro
IPR016152 PTrfase/Anion_transptr
IPR002178 PTS_EIIA_type-2_dom
IPR036095 PTS_EIIB-like_sf
IPR013011 PTS_EIIB_2
IPR003501 PTS_EIIB_2/3
IPR013014 PTS_EIIC_2
IPR003353 PTS_IIB_fruc
IPR006327 PTS_IIC_fruc
PfamiView protein in Pfam
PF00359 PTS_EIIA_2, 1 hit
PF02302 PTS_IIB, 1 hit
SUPFAMiSSF52794 SSF52794, 1 hit
SSF55804 SSF55804, 1 hit
TIGRFAMsiTIGR00829 FRU, 1 hit
TIGR01427 PTS_IIC_fructo, 1 hit
PROSITEiView protein in PROSITE
PS51094 PTS_EIIA_TYPE_2, 1 hit
PS51099 PTS_EIIB_TYPE_2, 1 hit
PS51104 PTS_EIIC_TYPE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE6D757_CUTAC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E6D757
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 31, 2019
This is version 48 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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