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Protein

DNA polymerase

Gene

Tsp_09727

Organism
Trichinella spiralis (Trichina worm)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation, DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase
Biological processDNA replicationUniRule annotation
Ligand4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
ORF Names:Tsp_09727Imported
OrganismiTrichinella spiralis (Trichina worm)Imported
Taxonomic identifieri6334 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaEnopleaDorylaimiaTrichinellidaTrichinellidaeTrichinella
Proteomesi
  • UP000006823 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 439DNA_pol_B_exo1InterPro annotationAdd BLAST361
Domaini497 – 954DNA_pol_BInterPro annotationAdd BLAST458
Domaini1001 – 1174zf-DNA_PolInterPro annotationAdd BLAST174

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Keywords - Domaini

Zinc-fingerUniRule annotation

Phylogenomic databases

eggNOGiKOG0970 Eukaryota
COG0417 LUCA
InParanoidiE5SP52
KOiK02320
OMAiPKDCIFP
OrthoDBiEOG091G00RR

Family and domain databases

Gene3Di1.10.3200.20, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 2 hits
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR017964 DNA-dir_DNA_pol_B_CS
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR023211 DNA_pol_palm_dom_sf
IPR038256 Pol_alpha_znc_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR015088 Znf_DNA-dir_DNA_pol_B_alpha
PfamiView protein in Pfam
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08996 zf-DNA_Pol, 1 hit
PRINTSiPR00106 DNAPOLB
SMARTiView protein in SMART
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS00116 DNA_POLYMERASE_B, 1 hit

Sequencei

Sequence statusi: Complete.

E5SP52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTSEQFSDL VIPSVVDVPD ETTAFPVNLK LSDISAEEEG GHQVVNFYYL
60 70 80 90 100
DAVEAGKKHP GIVYLFGKVQ HLIQKSWISC CLIVKNILRR IWILPRQTDL
110 120 130 140 150
QTGEPFKLED VHQELTELMN KLKIDEFRIK VTAFCLFNAL LLVKAVEKKF
160 170 180 190 200
WLNSDQYAQE AVYLELRYSV KNFLDCNFKY PALEANLTGK TFQAIFGTTS
210 220 230 240 250
SELELLILEM NIKGPRLMKI SNPTMAASQR TWCAVELIVN SSNIVPENVN
260 270 280 290 300
SLPPLRVLAI NFLTMPDPKT HHNEAFSTFT LFIVMVGLLS NDNLDLNNET
310 320 330 340 350
SALEQRWRHT CVIAKRPDLM FPSNFKSTLM DQKKTTVVIL NNERAILSAV
360 370 380 390 400
LTKILKIDPD IIVGHELLDF HLFNFINRAV TLQVPYPSRI SRLKNVTQTK
410 420 430 440 450
QKTQTKGLLQ QLTAGRMLCD AKVLAKELIR AKDFSLQEMA LEIFNERIEE
460 470 480 490 500
ILPQTIKNYF NSSTSLMHLV VKVLADAFLC WRICEKLRCL QLAIEITRAV
510 520 530 540 550
GGVLSKTLLG GRAERTEYLL LHAFDAQNYV YPEKVSHGGK QKVVVTSLDD
560 570 580 590 600
EEIIIGSKKA SYAGGLVLDP KKGLYDRIVL LLDFNSLYPS IIQEFNICFT
610 620 630 640 650
TVDLSPFTDP IKGSDEALPE IPDPEKAAGI LPKEIKRLVE SRRQLKSLMK
660 670 680 690 700
PGIPPDLFQQ YHIRQQALKI TANSVYGCLG FAASRFYAKP LAALITAKGR
710 720 730 740 750
EILTNTKLAV EKLGLEVIYG DTDSIMINSN LTSIDDALAM GKKVEKKKLG
760 770 780 790 800
RIAVVHFSST CVSLCFADQS RNEQTIQAAR KKKYAALSCE KRPDGSWQFK
810 820 830 840 850
KEVKGLDIVR RDWSPIAIEA GNYVINSILS DFTSDETAAR IREYLMKLTS
860 870 880 890 900
DVRQNKVVLG KFIIRKQLAK SPDEYQDAKG QPHVAVALRM NEKGSHFRQG
910 920 930 940 950
DVIPYAICLD QTNNQAMQRA YHFNEIQQGN MQIDFDYYLA QQIHPVVTRL
960 970 980 990 1000
CEPIESLDAA CLADWLGLKS ASYAKQSNFT PPTTDLATVS SSCSFFDHSY
1010 1020 1030 1040 1050
SEPFTVPCVE CGKIIEVTTL FSDMENIKLA LSKCPYGDCS FKPASNRQYL
1060 1070 1080 1090 1100
VSLLRKQIHK HVHQYYLGWY VCDDSTCRYR SRYVVMKLNS EGKLICPKCP
1110 1120 1130 1140 1150
SGILIREYSE KKLYNQLCFY FTIFDFPQAL MRLSKAKKQL ARLLPKMHLS
1160 1170 1180
VYETLATHAC SVLNDNAYGT INLGAVLKFY PKR
Length:1,183
Mass (Da):133,921
Last modified:March 8, 2011 - v1
Checksum:i0AC7D8B7E7F9EE3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABIR02001390 Genomic DNA Translation: EFV53426.1
RefSeqiXP_003374391.1, XM_003374343.1

Genome annotation databases

EnsemblMetazoaiEFV53426; EFV53426; EFV53426
GeneIDi10898371
KEGGitsp:Tsp_09727

Entry informationi

Entry nameiE5SP52_TRISP
AccessioniPrimary (citable) accession number: E5SP52
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 25, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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