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UniProtKB - E5RJU8 (E5RJU8_HUMAN)
Protein
Submitted name:
Ras GTPase-activating protein-binding protein 1
Gene
G3BP1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-KW
Keywordsi
Molecular function | RNA-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Ras GTPase-activating protein-binding protein 1Imported |
Gene namesi | Name:G3BP1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:30292, G3BP1 |
VEuPathDBi | HostDB:ENSG00000145907 |
Expressioni
Gene expression databases
Bgeei | ENSG00000145907, Expressed in female gonad and 259 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 11 – 131 | NTF2InterPro annotationAdd BLAST | 121 |
Phylogenomic databases
GeneTreei | ENSGT00390000011365 |
Family and domain databases
CDDi | cd00780, NTF2, 1 hit |
InterProi | View protein in InterPro IPR034375, G3BP1 IPR032710, NTF2-like_dom_sf IPR002075, NTF2_dom IPR018222, Nuclear_transport_factor_2_euk IPR039539, Ras_GTPase_bind_prot |
PANTHERi | PTHR10693, PTHR10693, 1 hit PTHR10693:SF21, PTHR10693:SF21, 1 hit |
Pfami | View protein in Pfam PF02136, NTF2, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit |
PROSITEi | View protein in PROSITE PS50177, NTF2_DOMAIN, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 34 potential isoforms that are computationally mapped.Show allAlign All
E5RJU8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK
60 70 80 90 100
PADAVYGQKE IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN
110 120 130 140 150
NNQALRRFMQ TFVLAPEVHL ALFLAQSLFL NQLFLQGGLV LFSYTYERTT
SLC
Computationally mapped potential isoform sequencesi
There are 34 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ13283 | G3BP1_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 G3BP | 466 | Annotation score: | ||
A0A7I2V5M7 | A0A7I2V5M7_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 476 | Annotation score: | ||
A0A7I2YQN9 | A0A7I2YQN9_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 426 | Annotation score: | ||
A0A7I2YQH0 | A0A7I2YQH0_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 134 | Annotation score: | ||
A0A7I2V2S5 | A0A7I2V2S5_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 170 | Annotation score: | ||
A0A7I2V651 | A0A7I2V651_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 304 | Annotation score: | ||
A0A7I2YQU8 | A0A7I2YQU8_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 334 | Annotation score: | ||
A0A7P0P2U7 | A0A7P0P2U7_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 367 | Annotation score: | ||
A0A7I2V2V1 | A0A7I2V2V1_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 151 | Annotation score: | ||
A0A7I2YQQ8 | A0A7I2YQQ8_HUMAN | Ras GTPase-activating protein-bindi... | G3BP1 | 63 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC091982 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000522761; ENSP00000430480; ENSG00000145907 ENST00000679289; ENSP00000504039; ENSG00000145907 |
UCSCi | uc063iwl.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC091982 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
ProteomicsDBi | 16714 |
Genome annotation databases
Ensembli | ENST00000522761; ENSP00000430480; ENSG00000145907 ENST00000679289; ENSP00000504039; ENSG00000145907 |
UCSCi | uc063iwl.1, human |
Organism-specific databases
HGNCi | HGNC:30292, G3BP1 |
OpenTargetsi | ENSG00000145907 |
VEuPathDBi | HostDB:ENSG00000145907 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000011365 |
Miscellaneous databases
ChiTaRSi | G3BP1, human |
Gene expression databases
Bgeei | ENSG00000145907, Expressed in female gonad and 259 other tissues |
Family and domain databases
CDDi | cd00780, NTF2, 1 hit |
InterProi | View protein in InterPro IPR034375, G3BP1 IPR032710, NTF2-like_dom_sf IPR002075, NTF2_dom IPR018222, Nuclear_transport_factor_2_euk IPR039539, Ras_GTPase_bind_prot |
PANTHERi | PTHR10693, PTHR10693, 1 hit PTHR10693:SF21, PTHR10693:SF21, 1 hit |
Pfami | View protein in Pfam PF02136, NTF2, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit |
PROSITEi | View protein in PROSITE PS50177, NTF2_DOMAIN, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | E5RJU8_HUMAN | |
Accessioni | E5RJU8Primary (citable) accession number: E5RJU8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 8, 2011 |
Last sequence update: | February 8, 2011 | |
Last modified: | January 19, 2022 | |
This is version 59 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |