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Protein
Submitted name:

Cadherin-17

Gene

CDH17

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin-17Imported
Gene namesi
Name:CDH17Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000079112.9
HGNCiHGNC:1756 CDH17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000079112

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500319862723 – 147Sequence analysisAdd BLAST125

Proteomic databases

MaxQBiE5RJT3
PeptideAtlasiE5RJT3
PRIDEiE5RJT3

Expressioni

Gene expression databases

BgeeiENSG00000079112 Expressed in 86 organ(s), highest expression level in colonic mucosa
ExpressionAtlasiE5RJT3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RJT3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 124CAInterPro annotationAdd BLAST86

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00740000115559

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
PfamiView protein in Pfam
PF00028 Cadherin, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 1 hit
SUPFAMiSSF49313 SSF49313, 1 hit
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E5RJT3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILQAHLHSL CLLMLYLATG YGQEGKFSGP LKPMTFSIYE GQEPSQIIFQ
60 70 80 90 100
FKANPPAVTF ELTGETDNIF VIEREGLLYY NRALDRETRS THNLQVAALD
110 120 130 140
ANGIIVEGPV PITIKVKDIN DNRPTFLQSK YEGSVRQNSR PGKPFLY
Length:147
Mass (Da):16,564
Last modified:February 8, 2011 - v1
Checksum:i8DCCCFD614E23FED
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q12864CAD17_HUMAN
Cadherin-17
CDH17
832Annotation score:
E7EN24E7EN24_HUMAN
Cadherin-17
CDH17
580Annotation score:
H0YBL0H0YBL0_HUMAN
Cadherin-17
CDH17
90Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei147Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003351 Genomic DNA No translation available.
AP003478 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000521491; ENSP00000428189; ENSG00000079112
UCSCiuc064oqa.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003351 Genomic DNA No translation available.
AP003478 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE5RJT3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE5RJT3
PeptideAtlasiE5RJT3
PRIDEiE5RJT3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000521491; ENSP00000428189; ENSG00000079112
UCSCiuc064oqa.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000079112.9
HGNCiHGNC:1756 CDH17
OpenTargetsiENSG00000079112
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00740000115559

Miscellaneous databases

ChiTaRSiCDH17 human

Gene expression databases

BgeeiENSG00000079112 Expressed in 86 organ(s), highest expression level in colonic mucosa
ExpressionAtlasiE5RJT3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
PfamiView protein in Pfam
PF00028 Cadherin, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 1 hit
SUPFAMiSSF49313 SSF49313, 1 hit
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RJT3_HUMAN
AccessioniPrimary (citable) accession number: E5RJT3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 7, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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