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Entry version 76 (07 Apr 2021)
Sequence version 2 (14 Dec 2011)
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Protein

Ankyrin repeat domain-containing protein 65

Gene

ANKRD65

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
E5RJM6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 65
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANKRD65
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:42950, ANKRD65

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_E5RJM6

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000235098.8

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000235098

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
E5RJM6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ANKRD65

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004144841 – 399Ankyrin repeat domain-containing protein 65Add BLAST399

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E5RJM6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
E5RJM6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E5RJM6

PeptideAtlas

More...
PeptideAtlasi
E5RJM6

PRoteomics IDEntifications database

More...
PRIDEi
E5RJM6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
16650 [E5RJM6-1]
16651 [E5RJM6-2]

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E5RJM6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000235098, Expressed in right uterine tube and 149 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E5RJM6, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000235098, Tissue enhanced (brain, fallopian tube)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
137829, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000445688

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
E5RJM6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E5RJM6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati40 – 69ANK 1Add BLAST30
Repeati73 – 102ANK 2Add BLAST30
Repeati106 – 135ANK 3Add BLAST30
Repeati139 – 168ANK 4Add BLAST30
Repeati176 – 205ANK 5Add BLAST30
Repeati207 – 231ANK 6Add BLAST25
Repeati235 – 264ANK 7Add BLAST30
Repeati268 – 297ANK 8Add BLAST30
Repeati301 – 330ANK 9Add BLAST30
Repeati334 – 363ANK 10Add BLAST30

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4177, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163707

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_2849024_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E5RJM6

Identification of Orthologs from Complete Genome Data

More...
OMAi
WHGHSRV

Database of Orthologous Groups

More...
OrthoDBi
812341at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
E5RJM6

TreeFam database of animal gene trees

More...
TreeFami
TF329520

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796, Ank_2, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415, ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403, SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: E5RJM6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDSQRPEPRE EEEEEQELRW MELDSEEALG TRTEGPSVVQ GWGHLLQAVW
60 70 80 90 100
RGPAGLVTQL LRQGASVEER DHAGRTPLHL AVLRGHAPLV RLLLQRGAPV
110 120 130 140 150
GAVDRAGRTA LHEAAWHGHS RVAELLLQRG ASAAARSGTG LTPLHWAAAL
160 170 180 190 200
GHTLLAARLL EAPGPGPAAA EAEDARGWTA AHWAAAGGRL AVLELLAAGG
210 220 230 240 250
AGLDGALLVA AAAGRGAALR FLLARGARVD ARDGAGATAL GLAAALGRSQ
260 270 280 290 300
DIEVLLGHGA DPGIRDRHGR SALHRAAARG HLLAVQLLVT QGAEVDARDT
310 320 330 340 350
LGLTPLHHAS REGHVEVAGC LLDRGAQVDA TGWLRKTPLH LAAERGHGPT
360 370 380 390
VGLLLSRGAS PTLRTQWAEV AQMPEGDLPQ ALPELGGGEK ECEGIESTG
Length:399
Mass (Da):41,497
Last modified:December 14, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i13AE59F52E54CF4A
GO
Isoform 2 (identifier: E5RJM6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     71-173: DHAGRTPLHL...GPGPAAAEAE → TLRCCWATGQ...EGMGLPWGFC
     174-399: Missing.

Show »
Length:174
Mass (Da):19,375
Checksum:iD9F1F20E2157F6E8
GO
Isoform 3 (identifier: E5RJM6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     65-65: A → H
     66-399: Missing.

Show »
Length:65
Mass (Da):7,466
Checksum:i8A801D058E1262DA
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04596265A → H in isoform 3. 1 Publication1
Alternative sequenceiVSP_04596366 – 399Missing in isoform 3. 1 PublicationAdd BLAST334
Alternative sequenceiVSP_04208571 – 173DHAGR…AAEAE → TLRCCWATGQTQASGTGMAA LRCTGLPPEDTCLPSSCWSP RGPRWMRGTPWASHPCITPL GKATWRLPAACWTGVPRWML PAGSERPPYTWLQSEGMGLP WGFC in isoform 2. 1 PublicationAdd BLAST103
Alternative sequenceiVSP_042086174 – 399Missing in isoform 2. 1 PublicationAdd BLAST226

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL391244 Genomic DNA No translation available.
BC063445 mRNA No translation available.
BC094869 mRNA No translation available.
AI522076 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS55558.1 [E5RJM6-1]
CCDS57962.1 [E5RJM6-2]
CCDS57963.1 [E5RJM6-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001138682.1, NM_001145210.2 [E5RJM6-1]
NP_001230464.1, NM_001243535.1 [E5RJM6-2]
NP_001230465.1, NM_001243536.1 [E5RJM6-3]
XP_005244809.1, XM_005244752.4 [E5RJM6-1]
XP_006710710.1, XM_006710647.3 [E5RJM6-1]
XP_011539791.1, XM_011541489.2 [E5RJM6-1]
XP_016856813.1, XM_017001324.1 [E5RJM6-1]
XP_016856814.1, XM_017001325.1
XP_016856815.1, XM_017001326.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000427211; ENSP00000428419; ENSG00000235098 [E5RJM6-2]
ENST00000442470; ENSP00000428201; ENSG00000235098 [E5RJM6-2]
ENST00000454272; ENSP00000482314; ENSG00000235098 [E5RJM6-1]
ENST00000520296; ENSP00000429035; ENSG00000235098 [E5RJM6-3]
ENST00000537107; ENSP00000445688; ENSG00000235098 [E5RJM6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
441869

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:441869

UCSC genome browser

More...
UCSCi
uc001afp.3, human [E5RJM6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL391244 Genomic DNA No translation available.
BC063445 mRNA No translation available.
BC094869 mRNA No translation available.
AI522076 mRNA No translation available.
CCDSiCCDS55558.1 [E5RJM6-1]
CCDS57962.1 [E5RJM6-2]
CCDS57963.1 [E5RJM6-3]
RefSeqiNP_001138682.1, NM_001145210.2 [E5RJM6-1]
NP_001230464.1, NM_001243535.1 [E5RJM6-2]
NP_001230465.1, NM_001243536.1 [E5RJM6-3]
XP_005244809.1, XM_005244752.4 [E5RJM6-1]
XP_006710710.1, XM_006710647.3 [E5RJM6-1]
XP_011539791.1, XM_011541489.2 [E5RJM6-1]
XP_016856813.1, XM_017001324.1 [E5RJM6-1]
XP_016856814.1, XM_017001325.1
XP_016856815.1, XM_017001326.1

3D structure databases

SMRiE5RJM6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi137829, 2 interactors
STRINGi9606.ENSP00000445688

PTM databases

PhosphoSitePlusiE5RJM6

Genetic variation databases

BioMutaiANKRD65

Proteomic databases

jPOSTiE5RJM6
MassIVEiE5RJM6
PaxDbiE5RJM6
PeptideAtlasiE5RJM6
PRIDEiE5RJM6
ProteomicsDBi16650 [E5RJM6-1]
16651 [E5RJM6-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
58071, 33 antibodies

The DNASU plasmid repository

More...
DNASUi
441869

Genome annotation databases

EnsembliENST00000427211; ENSP00000428419; ENSG00000235098 [E5RJM6-2]
ENST00000442470; ENSP00000428201; ENSG00000235098 [E5RJM6-2]
ENST00000454272; ENSP00000482314; ENSG00000235098 [E5RJM6-1]
ENST00000520296; ENSP00000429035; ENSG00000235098 [E5RJM6-3]
ENST00000537107; ENSP00000445688; ENSG00000235098 [E5RJM6-1]
GeneIDi441869
KEGGihsa:441869
UCSCiuc001afp.3, human [E5RJM6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
441869

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ANKRD65
HGNCiHGNC:42950, ANKRD65
HPAiENSG00000235098, Tissue enhanced (brain, fallopian tube)
neXtProtiNX_E5RJM6
OpenTargetsiENSG00000235098
VEuPathDBiHostDB:ENSG00000235098.8

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4177, Eukaryota
GeneTreeiENSGT00940000163707
HOGENOMiCLU_2849024_0_0_1
InParanoidiE5RJM6
OMAiWHGHSRV
OrthoDBi812341at2759
PhylomeDBiE5RJM6
TreeFamiTF329520

Enzyme and pathway databases

PathwayCommonsiE5RJM6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
441869, 28 hits in 978 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
441869
PharosiE5RJM6, Tdark

Protein Ontology

More...
PROi
PR:E5RJM6
RNActiE5RJM6, protein

Gene expression databases

BgeeiENSG00000235098, Expressed in right uterine tube and 149 other tissues
GenevisibleiE5RJM6, HS

Family and domain databases

Gene3Di1.25.40.20, 4 hits
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF12796, Ank_2, 2 hits
PRINTSiPR01415, ANKYRIN
SMARTiView protein in SMART
SM00248, ANK, 9 hits
SUPFAMiSSF48403, SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiANR65_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E5RJM6
Secondary accession number(s): J3KR93
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 7, 2021
This is version 76 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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