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Protein
Submitted name:

Brefeldin A-inhibited guanine nucleotide-exchange protein 1

Gene

ARFGEF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Brefeldin A-inhibited guanine nucleotide-exchange protein 1Imported
Gene namesi
Name:ARFGEF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000066777.8
HGNCiHGNC:15772 ARFGEF1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000066777

PTM / Processingi

Proteomic databases

PeptideAtlasiE5RHZ1
PRIDEiE5RHZ1

Expressioni

Gene expression databases

BgeeiENSG00000066777 Expressed in 228 organ(s), highest expression level in female gonad
ExpressionAtlasiE5RHZ1 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0929 Eukaryota
COG5307 LUCA
GeneTreeiENSGT00760000119036

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E5RHZ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XRLLLMKKSA KLNLQQLELI QTIDNIVFFP ATSKKEDAEN LAAAQRDAVD
60 70 80 90 100
FDVRVDTQDQ GMYRFLTSQQ LFKLLDCLLE SHRFAKAFNS NNEQRTALWK
110 120 130 140 150
AGFKGKSKPN LLKQETSSLA CGLRILFRMY MDESRVSAWE EVQQRLLNVC
160 170 180 190
SEALSYFLTL TSESHREAWT NLLLLFLTKV LKISDNRTKR TL
Length:192
Mass (Da):22,225
Last modified:October 14, 2015 - v2
Checksum:iD9235C75066B0FBE
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y6D6BIG1_HUMAN
Brefeldin A-inhibited guanine nucle...
ARFGEF1 ARFGEP1, BIG1
1,849Annotation score:
E5RIF2E5RIF2_HUMAN
Brefeldin A-inhibited guanine nucle...
ARFGEF1
1,279Annotation score:
E5RJN9E5RJN9_HUMAN
Brefeldin A-inhibited guanine nucle...
ARFGEF1
118Annotation score:
E5RHL7E5RHL7_HUMAN
Brefeldin A-inhibited guanine nucle...
ARFGEF1
825Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021321 Genomic DNA No translation available.
AC087359 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000518789; ENSP00000429560; ENSG00000066777
UCSCiuc064nme.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021321 Genomic DNA No translation available.
AC087359 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE5RHZ1
PRIDEiE5RHZ1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000518789; ENSP00000429560; ENSG00000066777
UCSCiuc064nme.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000066777.8
HGNCiHGNC:15772 ARFGEF1
OpenTargetsiENSG00000066777
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0929 Eukaryota
COG5307 LUCA
GeneTreeiENSGT00760000119036

Miscellaneous databases

ChiTaRSiARFGEF1 human

Gene expression databases

BgeeiENSG00000066777 Expressed in 228 organ(s), highest expression level in female gonad
ExpressionAtlasiE5RHZ1 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiE5RHZ1_HUMAN
AccessioniPrimary (citable) accession number: E5RHZ1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: October 14, 2015
Last modified: September 12, 2018
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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