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Protein
Submitted name:

Syndecan-2

Gene

SDC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Syndecan-2Imported
Gene namesi
Name:SDC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000169439.11
HGNCiHGNC:10659 SDC2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei116 – 140HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000169439

PTM / Processingi

Proteomic databases

PeptideAtlasiE5RHU3
PRIDEiE5RHU3

Expressioni

Gene expression databases

BgeeiENSG00000169439 Expressed in 231 organ(s), highest expression level in tibia
ExpressionAtlasiE5RHU3 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini109 – 145SyndecanInterPro annotationAdd BLAST37

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IW5I Eukaryota
ENOG4111QSA LUCA
GeneTreeiENSGT00530000063116

Family and domain databases

InterProiView protein in InterPro
IPR001050 Syndecan
IPR031201 Syndecan-2
IPR027789 Syndecan/Neurexin_dom
PANTHERiPTHR10915 PTHR10915, 1 hit
PTHR10915:SF6 PTHR10915:SF6, 1 hit
PfamiView protein in Pfam
PF01034 Syndecan, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E5RHU3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYLDNSSIEE ASGVYPIDDD DYASASGSGA DEDVESPELT TSRPLPKILL
60 70 80 90 100
TSAAPKVETT TLNIQNKIPA QTKSPEETDK EKVHLSDSER KMDPAEEDTN
110 120 130 140
VYTEKHSDSL FKRTEVLAAV IAGGVIGFLF AIFLILLLVY RMRKK
Length:145
Mass (Da):15,981
Last modified:June 26, 2013 - v2
Checksum:i9CD54A549102BB01
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P34741SDC2_HUMAN
Syndecan-2
SDC2 HSPG1
201Annotation score:
E7ESK6E7ESK6_HUMAN
Syndecan
SDC2
165Annotation score:
E9PBI9E9PBI9_HUMAN
Syndecan
SDC2
172Annotation score:
E5RJB8E5RJB8_HUMAN
Syndecan-2
SDC2
137Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei145Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003477 Genomic DNA No translation available.
AP003548 Genomic DNA No translation available.
KC877279 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000523877; ENSP00000429662; ENSG00000169439
UCSCiuc064our.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003477 Genomic DNA No translation available.
AP003548 Genomic DNA No translation available.
KC877279 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE5RHU3
PRIDEiE5RHU3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000523877; ENSP00000429662; ENSG00000169439
UCSCiuc064our.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000169439.11
HGNCiHGNC:10659 SDC2
OpenTargetsiENSG00000169439
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IW5I Eukaryota
ENOG4111QSA LUCA
GeneTreeiENSGT00530000063116

Miscellaneous databases

ChiTaRSiSDC2 human

Gene expression databases

BgeeiENSG00000169439 Expressed in 231 organ(s), highest expression level in tibia
ExpressionAtlasiE5RHU3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001050 Syndecan
IPR031201 Syndecan-2
IPR027789 Syndecan/Neurexin_dom
PANTHERiPTHR10915 PTHR10915, 1 hit
PTHR10915:SF6 PTHR10915:SF6, 1 hit
PfamiView protein in Pfam
PF01034 Syndecan, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RHU3_HUMAN
AccessioniPrimary (citable) accession number: E5RHU3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: June 26, 2013
Last modified: September 12, 2018
This is version 56 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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