Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Integrin beta-2

Gene

ITGB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIntegrinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-2Imported
Gene namesi
Name:ITGB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

EuPathDBiHostDB:ENSG00000160255.16
HGNCiHGNC:6155 ITGB2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000160255

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501457086523 – 49Sequence analysisAdd BLAST27

Proteomic databases

MaxQBiE5RHT0
PRIDEiE5RHT0

Expressioni

Gene expression databases

BgeeiENSG00000160255

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 48PSI_integrinInterPro annotationAdd BLAST26

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1226 Eukaryota
ENOG410XP60 LUCA
GeneTreeiENSGT00760000119064

Family and domain databases

InterProiView protein in InterPro
IPR033760 Integrin_beta_N
IPR015812 Integrin_bsu
IPR015439 Integrin_bsu-2
PANTHERiPTHR10082 PTHR10082, 1 hit
PTHR10082:SF15 PTHR10082:SF15, 1 hit
PfamiView protein in Pfam
PF17205 PSI_integrin, 1 hit

Sequencei

Sequence statusi: Fragment.

E5RHT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKL
Length:49
Mass (Da):5,269
Last modified:February 8, 2011 - v1
Checksum:iC75444E38FDBB067
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei49Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773603 Genomic DNA No translation available.
AL844907 Genomic DNA No translation available.
AL844908 Genomic DNA No translation available.
KC877928 Genomic DNA No translation available.
KJ528562 Genomic DNA Translation: AHZ44414.1
KJ528563 Genomic DNA Translation: AHZ44415.1
KJ528564 Genomic DNA Translation: AHZ44416.1
UniGeneiHs.375957

Genome annotation databases

EnsembliENST00000521995; ENSP00000429683; ENSG00000160255
UCSCiuc062auo.1 human

Similar proteinsi

Entry informationi

Entry nameiE5RHT0_HUMAN
AccessioniPrimary (citable) accession number: E5RHT0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: July 18, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health