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Protein
Submitted name:

Cell cycle and apoptosis regulator protein 2

Gene

CCAR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Cell cycle and apoptosis regulator protein 2Imported
Gene namesi
Name:CCAR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000158941.16
HGNCiHGNC:23360 CCAR2

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000158941

PTM / Processingi

Proteomic databases

EPDiE5RHJ4
MaxQBiE5RHJ4
PeptideAtlasiE5RHJ4
PRIDEiE5RHJ4

Expressioni

Gene expression databases

BgeeiENSG00000158941 Expressed in 190 organ(s), highest expression level in right testis
ExpressionAtlasiE5RHJ4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RHJ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini157 – 277DBC1InterPro annotationAdd BLAST121

Phylogenomic databases

eggNOGiKOG4246 Eukaryota
ENOG4111FW4 LUCA
GeneTreeiENSGT00530000063672

Family and domain databases

InterProiView protein in InterPro
IPR025224 CCAR1/CCAR2
IPR028811 CCAR2
IPR025954 DBC1/CARP1_inactive_NUDIX_dom
PANTHERiPTHR14304 PTHR14304, 1 hit
PTHR14304:SF12 PTHR14304:SF12, 1 hit
PfamiView protein in Pfam
PF14443 DBC1, 1 hit
SMARTiView protein in SMART
SM01122 DBC1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

E5RHJ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWFLTVGDGS TSSDDYDSKK RKQRAGGEPW GAKKPRHDLP PYRVHLTPYT
60 70 80 90 100
VDSPICDFLE LQRRYRSLLV PSDFLSVHLS WLSAFPLSQP FSLHHPSRIQ
110 120 130 140 150
VSSEKEAAPD AGAEPITADS DPAYSSKVLL LSSPGLEELY RCCMLFVDDM
160 170 180 190 200
AEPRETPEHP LKQIKFLLGR KEEEAVLVGG EWSPSLDGLD PQADPQVLVR
210 220 230 240 250
TAIRCAQAQT GIDLSGCTKW WRFAEFQYLQ PGPPRRLQTV VVYLPDVWTI
260 270
MPTLEEWEAL CQQKAAEAAP PTQEAQG
Length:277
Mass (Da):31,090
Last modified:February 8, 2011 - v1
Checksum:iC07DC13B35C4C66D
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8N163CCAR2_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2 DBC1, KIAA1967
923Annotation score:
G3V119G3V119_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2 KIAA1967, hCG_2043023
598Annotation score:
H0YB24H0YB24_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2
615Annotation score:
A0A087X2B6A0A087X2B6_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2
272Annotation score:
E5RGU7E5RGU7_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2
150Annotation score:
H0YC69H0YC69_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2
148Annotation score:
H0YC58H0YC58_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2
183Annotation score:
E5RHH8E5RHH8_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2
81Annotation score:
E5RFJ3E5RFJ3_HUMAN
Cell cycle and apoptosis regulator ...
CCAR2
162Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei277Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC037459 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000522599; ENSP00000429739; ENSG00000158941
UCSCiuc064lbt.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC037459 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE5RHJ4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiE5RHJ4
MaxQBiE5RHJ4
PeptideAtlasiE5RHJ4
PRIDEiE5RHJ4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000522599; ENSP00000429739; ENSG00000158941
UCSCiuc064lbt.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000158941.16
HGNCiHGNC:23360 CCAR2
OpenTargetsiENSG00000158941
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4246 Eukaryota
ENOG4111FW4 LUCA
GeneTreeiENSGT00530000063672

Miscellaneous databases

ChiTaRSiCCAR2 human

Gene expression databases

BgeeiENSG00000158941 Expressed in 190 organ(s), highest expression level in right testis
ExpressionAtlasiE5RHJ4 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR025224 CCAR1/CCAR2
IPR028811 CCAR2
IPR025954 DBC1/CARP1_inactive_NUDIX_dom
PANTHERiPTHR14304 PTHR14304, 1 hit
PTHR14304:SF12 PTHR14304:SF12, 1 hit
PfamiView protein in Pfam
PF14443 DBC1, 1 hit
SMARTiView protein in SMART
SM01122 DBC1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RHJ4_HUMAN
AccessioniPrimary (citable) accession number: E5RHJ4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 12, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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