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Protein
Submitted name:

CCR4-NOT transcription complex subunit 8

Gene

CNOT8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CCR4-NOT transcription complex subunit 8Imported
Gene namesi
Name:CNOT8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000155508.13
HGNCiHGNC:9207 CNOT8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155508

PTM / Processingi

Proteomic databases

PRIDEiE5RHG0

Expressioni

Gene expression databases

BgeeiENSG00000155508 Expressed in 233 organ(s), highest expression level in right lung
ExpressionAtlasiE5RHG0 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0304 Eukaryota
COG5228 LUCA
GeneTreeiENSGT00390000000080

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR039637 CNOT7/CNOT8/Pop2
IPR027212 Cnot8
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PANTHERiPTHR10797 PTHR10797, 1 hit
PTHR10797:SF1 PTHR10797:SF1, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

E5RHG0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPAALVENSQ VICEVWASNL EEEMRKIREI VLSYSYIAMD TEFPGVVVRP

IGEFR
Length:55
Mass (Da):6,317
Last modified:February 8, 2011 - v1
Checksum:i58114F636DC4B9AD
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UFF9CNOT8_HUMAN
CCR4-NOT transcription complex subu...
CNOT8 CALIF, POP2
292Annotation score:
B7Z9U0B7Z9U0_HUMAN
cDNA, FLJ78954, highly similar to C...
CNOT8
128Annotation score:
E5RIL2E5RIL2_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
225Annotation score:
E5RFJ4E5RFJ4_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
90Annotation score:
E5RHP3E5RHP3_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
121Annotation score:
E5RHL9E5RHL9_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
117Annotation score:
E5RGE4E5RGE4_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
132Annotation score:
E5RHD6E5RHD6_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
52Annotation score:
E5RJC5E5RJC5_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
118Annotation score:
E5RIU0E5RIU0_HUMAN
CCR4-NOT transcription complex subu...
CNOT8
85Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei55Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112169 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000518028; ENSP00000429810; ENSG00000155508
ENST00000519430; ENSP00000429310; ENSG00000155508
UCSCiuc063jat.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112169 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiE5RHG0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000518028; ENSP00000429810; ENSG00000155508
ENST00000519430; ENSP00000429310; ENSG00000155508
UCSCiuc063jat.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000155508.13
HGNCiHGNC:9207 CNOT8
OpenTargetsiENSG00000155508
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0304 Eukaryota
COG5228 LUCA
GeneTreeiENSGT00390000000080

Miscellaneous databases

ChiTaRSiCNOT8 human

Gene expression databases

BgeeiENSG00000155508 Expressed in 233 organ(s), highest expression level in right lung
ExpressionAtlasiE5RHG0 baseline and differential

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR039637 CNOT7/CNOT8/Pop2
IPR027212 Cnot8
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PANTHERiPTHR10797 PTHR10797, 1 hit
PTHR10797:SF1 PTHR10797:SF1, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RHG0_HUMAN
AccessioniPrimary (citable) accession number: E5RHG0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 7, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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