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Protein
Submitted name:

Transcription initiation factor TFIID subunit 6

Gene

TAF6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription initiation factor TFIID subunit 6Imported
Gene namesi
Name:TAF6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000106290.14
HGNCiHGNC:11540 TAF6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000106290

PTM / Processingi

Proteomic databases

EPDiE5RHA1
MaxQBiE5RHA1
PeptideAtlasiE5RHA1
PRIDEiE5RHA1

Expressioni

Gene expression databases

BgeeiENSG00000106290 Expressed in 230 organ(s), highest expression level in right frontal lobe
ExpressionAtlasiE5RHA1 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 68TAFInterPro annotationAdd BLAST57

Phylogenomic databases

GeneTreeiENSGT00640000091486

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR037796 TAF6
IPR004823 TAF_TATA-bd
PANTHERiPTHR10221 PTHR10221, 1 hit
PfamiView protein in Pfam
PF02969 TAF, 1 hit
SMARTiView protein in SMART
SM00803 TAF, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

E5RHA1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEEKKLKLS NTVLPSESMK VVAESMGIAQ IQEETCQLLT DEDALKFMHM
60 70 80 90 100
GKRQKLTTSD IDYALKLKNV EPLYGFHAQE FIPFRFASGG GRELYFYEEK
110 120 130 140
EVDLSDIINT PLPRVPLDVC LKAHWLSIEG CQPAIPENPP P
Length:141
Mass (Da):15,939
Last modified:February 8, 2011 - v1
Checksum:iE9175B49E134813C
GO

Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P49848TAF6_HUMAN
Transcription initiation factor TFI...
TAF6 TAF2E, TAFII70
677Annotation score:
J3KR72J3KR72_HUMAN
Transcription initiation factor TFI...
TAF6
734Annotation score:
C9JTY6C9JTY6_HUMAN
Transcription initiation factor TFI...
TAF6
255Annotation score:
C9JFL8C9JFL8_HUMAN
Transcription initiation factor TFI...
TAF6
232Annotation score:
F8WEJ7F8WEJ7_HUMAN
Transcription initiation factor TFI...
TAF6
114Annotation score:
C9J7C4C9J7C4_HUMAN
Transcription initiation factor TFI...
TAF6
114Annotation score:
C9JIS2C9JIS2_HUMAN
Transcription initiation factor TFI...
TAF6
134Annotation score:
C9J088C9J088_HUMAN
Transcription initiation factor TFI...
TAF6
156Annotation score:
C9JHQ8C9JHQ8_HUMAN
Transcription initiation factor TFI...
TAF6
76Annotation score:
E5RKA5E5RKA5_HUMAN
Transcription initiation factor TFI...
TAF6
113Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei141Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073842 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000523306; ENSP00000428639; ENSG00000106290
UCSCiuc064gae.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073842 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiE5RHA1
MaxQBiE5RHA1
PeptideAtlasiE5RHA1
PRIDEiE5RHA1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000523306; ENSP00000428639; ENSG00000106290
UCSCiuc064gae.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000106290.14
HGNCiHGNC:11540 TAF6
OpenTargetsiENSG00000106290
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00640000091486

Miscellaneous databases

ChiTaRSiTAF6 human

Gene expression databases

BgeeiENSG00000106290 Expressed in 230 organ(s), highest expression level in right frontal lobe
ExpressionAtlasiE5RHA1 baseline and differential

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR037796 TAF6
IPR004823 TAF_TATA-bd
PANTHERiPTHR10221 PTHR10221, 1 hit
PfamiView protein in Pfam
PF02969 TAF, 1 hit
SMARTiView protein in SMART
SM00803 TAF, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RHA1_HUMAN
AccessioniPrimary (citable) accession number: E5RHA1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 12, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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