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Protein
Submitted name:

Fatty acid desaturase 2

Gene

FADS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Fatty acid desaturase 2Imported
Gene namesi
Name:FADS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000134824.13
HGNCiHGNC:3575 FADS2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134824

PTM / Processingi

Proteomic databases

PeptideAtlasiE5RGZ5
PRIDEiE5RGZ5

Expressioni

Gene expression databases

BgeeiENSG00000134824 Expressed in 190 organ(s), highest expression level in right adrenal gland
ExpressionAtlasiE5RGZ5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RGZ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 101FA_desaturaseInterPro annotationAdd BLAST67

Phylogenomic databases

eggNOGiKOG4232 Eukaryota
ENOG410XVSZ LUCA
GeneTreeiENSGT00510000046574

Family and domain databases

InterProiView protein in InterPro
IPR005804 FA_desaturase_dom
PfamiView protein in Pfam
PF00487 FA_desaturase, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E5RGZ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLFKTNHVF FLLLLAHIIA LESIAWFTVF YFGNGWIPTL ITAFVLATSQ
60 70 80 90 100
AQAGWLQHDY GHLSVYRKPK WNHLVHKFVI GHLKGASANW WNHRHFQHHA

KPN
Length:103
Mass (Da):12,056
Last modified:February 8, 2011 - v1
Checksum:iF14D1BBE926CE3F4
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O95864FADS2_HUMAN
Fatty acid desaturase 2
FADS2
444Annotation score:
F5H622F5H622_HUMAN
Fatty acid desaturase 2
FADS2
151Annotation score:
F5GZ92F5GZ92_HUMAN
Fatty acid desaturase 2
FADS2
95Annotation score:
E5RGD8E5RGD8_HUMAN
Fatty acid desaturase 2
FADS2
93Annotation score:
E5RHL3E5RHL3_HUMAN
Fatty acid desaturase 2
FADS2
52Annotation score:
F5GZU2F5GZU2_HUMAN
Fatty acid desaturase 2
FADS2
55Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei103Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002380 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000518606; ENSP00000430054; ENSG00000134824
UCSCiuc058cfg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002380 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE5RGZ5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE5RGZ5
PRIDEiE5RGZ5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000518606; ENSP00000430054; ENSG00000134824
UCSCiuc058cfg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000134824.13
HGNCiHGNC:3575 FADS2
OpenTargetsiENSG00000134824
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4232 Eukaryota
ENOG410XVSZ LUCA
GeneTreeiENSGT00510000046574

Miscellaneous databases

ChiTaRSiFADS2 human

Gene expression databases

BgeeiENSG00000134824 Expressed in 190 organ(s), highest expression level in right adrenal gland
ExpressionAtlasiE5RGZ5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR005804 FA_desaturase_dom
PfamiView protein in Pfam
PF00487 FA_desaturase, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RGZ5_HUMAN
AccessioniPrimary (citable) accession number: E5RGZ5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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