Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Integrin beta-2

Gene

ITGB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-2Imported
Gene namesi
Name:ITGB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

EuPathDBiHostDB:ENSG00000160255.16
HGNCiHGNC:6155 ITGB2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000160255

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500319681221 – 71Sequence analysisAdd BLAST51

Expressioni

Gene expression databases

BgeeiENSG00000160255 Expressed in 187 organ(s), highest expression level in blood
ExpressionAtlasiE5RGK9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RGK9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000119064

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.iShow all

E5RGK9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLGLRPPLLA LVGLLSLGCG RPRAPTHQPA SSLSPLSGVH EVQGQQLPGM
60 70
HRVGARLHLV PEAELHRAGG S
Length:71
Mass (Da):7,384
Last modified:February 8, 2011 - v1
Checksum:iCEA5495081DD9C1D
GO

Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P05107ITB2_HUMAN
Integrin beta-2
ITGB2 CD18, MFI7
769Annotation score:
D3DSM0D3DSM0_HUMAN
Integrin beta
ITGB2 hCG_401305
712Annotation score:
E7EVZ9E7EVZ9_HUMAN
Integrin beta
ITGB2
166Annotation score:
E5RK25E5RK25_HUMAN
Integrin beta
ITGB2
160Annotation score:
J3KNI6J3KNI6_HUMAN
Integrin beta
ITGB2
322Annotation score:
E5RIG7E5RIG7_HUMAN
Integrin beta-2
ITGB2
120Annotation score:
A8MVG7A8MVG7_HUMAN
Integrin beta-2
ITGB2
108Annotation score:
E5RFI0E5RFI0_HUMAN
Integrin beta-2
ITGB2
70Annotation score:
E5RIE4E5RIE4_HUMAN
Integrin beta-2
ITGB2
93Annotation score:
E5RHT0E5RHT0_HUMAN
Integrin beta-2
ITGB2
49Annotation score:
There are more potential isoformsShow all

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773603 Genomic DNA No translation available.
AL844907 Genomic DNA No translation available.
AL844908 Genomic DNA No translation available.
KC877928 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000523323; ENSP00000427732; ENSG00000160255
UCSCiuc062aty.1 human

Similar proteinsi

Entry informationi

Entry nameiE5RGK9_HUMAN
AccessioniPrimary (citable) accession number: E5RGK9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 12, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again