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Protein
Submitted name:

Dynactin subunit 4

Gene

DCTN4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Dynactin subunit 4Imported
Gene namesi
Name:DCTN4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000132912.12
HGNCiHGNC:15518 DCTN4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132912

PTM / Processingi

Proteomic databases

MaxQBiE5RGG1
PeptideAtlasiE5RGG1
PRIDEiE5RGG1

Expressioni

Gene expression databases

BgeeiENSG00000132912 Expressed in 225 organ(s), highest expression level in cerebral cortex
ExpressionAtlasiE5RGG1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RGG1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3896 Eukaryota
ENOG410ZCK8 LUCA
GeneTreeiENSGT00390000006954

Family and domain databases

InterProiView protein in InterPro
IPR008603 DCTN4
PANTHERiPTHR13034 PTHR13034, 1 hit
PfamiView protein in Pfam
PF05502 Dynactin_p62, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E5RGG1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSAEAKLKK NRCANCFDCP GCMHTLSTRA TSISTQLPDD PAKTTMKKAY
60 70 80 90 100
YLACGFCRWT SRDVGMADKS VASGGWQEPE NPHTQRMNKL IEYYQQLAQK
110
EKVERDRKKL ARRR
Length:114
Mass (Da):13,061
Last modified:February 8, 2011 - v1
Checksum:i22059540330DF752
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UJW0DCTN4_HUMAN
Dynactin subunit 4
DCTN4
460Annotation score:
H9KVE0H9KVE0_HUMAN
Dynactin subunit 4
DCTN4
134Annotation score:
E5RK21E5RK21_HUMAN
Dynactin subunit 4
DCTN4
91Annotation score:
E5RI97E5RI97_HUMAN
Dynactin subunit 4
DCTN4
86Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei114Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008450 Genomic DNA No translation available.
AC008453 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000521533; ENSP00000430183; ENSG00000132912
UCSCiuc063isx.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008450 Genomic DNA No translation available.
AC008453 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE5RGG1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE5RGG1
PeptideAtlasiE5RGG1
PRIDEiE5RGG1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000521533; ENSP00000430183; ENSG00000132912
UCSCiuc063isx.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132912.12
HGNCiHGNC:15518 DCTN4
OpenTargetsiENSG00000132912
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3896 Eukaryota
ENOG410ZCK8 LUCA
GeneTreeiENSGT00390000006954

Miscellaneous databases

ChiTaRSiDCTN4 human

Gene expression databases

BgeeiENSG00000132912 Expressed in 225 organ(s), highest expression level in cerebral cortex
ExpressionAtlasiE5RGG1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR008603 DCTN4
PANTHERiPTHR13034 PTHR13034, 1 hit
PfamiView protein in Pfam
PF05502 Dynactin_p62, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE5RGG1_HUMAN
AccessioniPrimary (citable) accession number: E5RGG1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 12, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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